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Vestn Oftalmol ; 126(4): 10-4, 2010.
Article in Russian | MEDLINE | ID: mdl-20873150

ABSTRACT

Pupillary reactions and hemodynamic parameters in the ophthalmic and central retinal arteries were studied in patients with types 1 and 2 diabetes mellitus. The pupillary dilatation test in the dark and 2.5% irifrin and 1% mydriacyl tests revealed a reduction in the papillary dilatation amplitude in hyperglycemia in patients with diabetic retinopathy. The amplitude of pupillary dilatation did not change during all pupil reactions in patients without diabetic retinopathy with a glycemic gradient. Pupillary dysfunction was detected in patients with diabetic retinopathy, which is a poor predictor for microangiopathy. Color Doppler mapping is a technique for studying blood flow, which is widely used in most of research institutions now. The procedure for studying the ocular microcirculatory bed in relation to blood glucose levels is an innovation in examining eye hemodynamics in patients with diabetes mellitus.


Subject(s)
Diabetes Mellitus, Type 1/physiopathology , Diabetes Mellitus, Type 2/physiopathology , Diabetic Retinopathy/diagnosis , Hemodynamics , Pupil Disorders/physiopathology , Adult , Aged , Blood Glucose , Diabetes Mellitus, Type 1/complications , Diabetes Mellitus, Type 2/complications , Diabetic Retinopathy/physiopathology , Female , Humans , Male , Middle Aged , Pupil Disorders/etiology , Reflex, Pupillary , Retinal Artery/physiopathology
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