Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 10 de 10
Filter
Add more filters










Publication year range
1.
Childs Nerv Syst ; 39(7): 1941-1944, 2023 07.
Article in English | MEDLINE | ID: mdl-37014464

ABSTRACT

We report a nine-year-old male having malignant peripheral nerve sheath tumor (MPNST) of the frontal bone, represented with a twelve-month history of ptosis and proptosis in his right eye and enlarged rapidly in the last three months. Except for slight numbness at his one-third of the right forehead, he had no neurological deficit. The patient's both eyes were having normal eye movements, and he had no visual acuity or field loss. After surgery, we observed the patient with no recurrence for 4 years.


Subject(s)
Exophthalmos , Nerve Sheath Neoplasms , Neurofibrosarcoma , Male , Humans , Child , Nerve Sheath Neoplasms/surgery , Frontal Bone/diagnostic imaging , Frontal Bone/surgery , Frontal Bone/pathology , Exophthalmos/etiology
2.
J Orthop Surg (Hong Kong) ; 27(2): 2309499019840736, 2019.
Article in English | MEDLINE | ID: mdl-30955477

ABSTRACT

PURPOSE: Deep palmar tumors of the hand are very rare, and reported cases are usually benign. The most important issue is frequent anatomical variations with challenging surgical exposure and excision of these lesions. Some case reports or a small series of patients have been reported in the literature. The aim of this study was to present our experience with the deep palmar tumors of the hand. PATIENTS AND METHODS: In the study, retrospective analyses of 43 patients treated with deep palmar tumors of the hand between January 1998 and June 2015 were evaluated. Tumors and tumor-like pathologies of the deep palmar space of the hand were retrospectively evaluated according to age, gender, localization, preoperative symptoms, size, site, treatment methods, histopathology, and early and late complications. Statistics and data analyses were also performed. RESULTS: All 43 pathologies were benign, and histopathologic diagnoses were 10 lipomas, 8 ganglions, 5 giant cell tumor of the tendon sheath, 4 schwannomas, 3 hemangiomas, 3 palmar fibromatosis, 2 epidermal cysts, 2 neurofibroma, 1 angiolymphoid hyperplasia with eosinophilia, 1 granuloma, 1 calcifying aponeurotic fibroma, 1 digital fibroma, 1 foreign body granuloma, and 1 lipofibromatous hamartoma. The most common complication was temporary numbness and paresthesias of the digits. Marginal excision was performed in 40 patients, excision with nerve grafting in 2 patients (with neurofibroma) and carpal tunnel release in one patient with lipofibromatous hamartoma. CONCLUSION: In the deep palmar space of the hand, pathologies are closely associated with tendons, muscles, and neurovascular structures. Preoperative magnetic resonance imaging is helpful for the preoperative diagnosis, evaluating tumor extension, and successful surgical planning. Level of Evidence: IV Therapautic.


Subject(s)
Carpal Tunnel Syndrome/etiology , Fibroma, Ossifying/diagnosis , Orthopedic Procedures/methods , Soft Tissue Neoplasms/diagnosis , Tendons/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Carpal Tunnel Syndrome/diagnosis , Carpal Tunnel Syndrome/surgery , Child , Diagnosis, Differential , Female , Fibroma, Ossifying/complications , Fibroma, Ossifying/surgery , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Retrospective Studies , Soft Tissue Neoplasms/complications , Soft Tissue Neoplasms/surgery , Tendons/surgery , Young Adult
3.
Turk J Pediatr ; 61(5): 765-770, 2019.
Article in English | MEDLINE | ID: mdl-32105010

ABSTRACT

Yalçin K, Tüysüz G, Kazan S, Gürer EI, Karaali K, Küpesiz A, Güler E. An infant with intradural extramedullary synovial sarcoma: the youngest case in the literature. Turk J Pediatr 2019; 61: 765-770. Spinal cord involvement of synovial sarcoma is extremely rare. So far only two cases have been reported. Herein we describe the youngest case in the literature. She is 14-month-old and first presented with difficulty in walking ongoing for a week. Imagining showed a spinal cord mass at C5-T3 levels. The patient had gone under Decompressive surgery and histopathologic examination of the specimen revealed the presence of synovial sarcoma. Although the tumor regressed after chemotherapy, she was lost due to viral pneumonia. Synovial sarcoma should be kept in mind while evaluating spinal tumors even in infantile group.


Subject(s)
Sarcoma, Synovial/diagnosis , Sarcoma, Synovial/therapy , Spinal Cord Neoplasms/diagnosis , Spinal Cord Neoplasms/therapy , Age Factors , Female , Humans , Infant , Laminectomy
4.
Turk Patoloji Derg ; 34(1): 66-72, 2018.
Article in English | MEDLINE | ID: mdl-28984347

ABSTRACT

OBJECTIVE: Knowledge concerning treatment and care of hand lesions is often based on small case series, case reports and a few large general case series. The aim of this study is to present our experience with hand tumors' and tumor-like lesions' incidence, age range and localizations. MATERIAL AND METHOD: Between 2006-2016, 402 patients operated and histopathologically diagnosed with bone and soft tissue tumorous conditions of the hand were evaluated retrospectively. RESULTS: Three hundred sixty one out of 402 cases (89.8%) were soft tissue tumors and 41 cases (10.2%) were osseous tumors of the hand. A total of 10 malignant tumors (2.5%) were encountered in the hand. The average age of the patients was 41.9 years (ranged from 1 to 83 years). Among 361 soft tissue tumors, only 6 cases (1.6%) were malignant and they were squamous cell tumors (n=5) and synovial sarcoma (n=1). The most common soft tissue pathology was ganglion cyst (n=125). The most common bone tumor was enchondroma, diagnosed in 26 patients (6.4% of all patients). Primary malignant bone tumors were extremely rare in the hand; one osteosarcoma and one chondrosarcoma were reported. Metastatic tumors to the hand were seen in two patients; and they were lung carcinoma and chondrosarcoma metastasis. CONCLUSION: Up-date knowledge and a thorough understanding of the nature and demographic characteristics of the tumorous conditions of the hand are crucial for accurate diagnosis and appropriate treatment.


Subject(s)
Bone Neoplasms/pathology , Hand/pathology , Soft Tissue Neoplasms/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Humans , Infant , Male , Middle Aged , Retrospective Studies , Young Adult
5.
Eur J Dent ; 10(1): 139-143, 2016.
Article in English | MEDLINE | ID: mdl-27011753

ABSTRACT

Ameloblastic fibroma (AF) is rare benign odontogenic tumour which usually occurs in the first two decades of life. It can occur either the mandible or maxilla but it is most frequently found in the posterior region of the mandible. Treatment of AF in usual is a conservative approach, such as enucleation and curettage but the aggressive lesions require a radical approach. A more radical approach should be considered in older patients who have likely high recurrence tendency. This report describes a case of AF in a 38-year-old female patient identified during a routine radiographic exam. Tomographic examination through three-dimensional reconstruction indicated vestibular fenestration of the cortical bone, with involvement of lingual cortical bone as the lession extended to the posterior region. We removed the tumor under local anesthesia. In this case patient has continued to be followed frequently and has been disease-free for 3 years.

6.
Clin Neurol Neurosurg ; 126: 99-102, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25233492

ABSTRACT

Hemangiomas in the spinal epidural area are very rare lesions, and most of these lesions are of the cavernous type. Only seven cases of capillary hemangiomas have been reported in the English literature, and all of these cases occurred in adulthood. Here, we report on a 17-month-old girl who presented with an inability to walk. MRI revealed an epidural mass, which was diagnosed as an epidural capillary hemangioma in the thoracic region. To our best knowledge, this case is the first epidural capillary hemangioma case to occur in childhood that has been reported.


Subject(s)
Epidural Neoplasms/pathology , Hemangioma, Capillary/pathology , Female , Humans , Infant , Male , Middle Aged
7.
J Biomed Opt ; 14(5): 054021, 2009.
Article in English | MEDLINE | ID: mdl-19895123

ABSTRACT

We have investigated the potential application of elastic light single-scattering spectroscopy (ELSSS) as an adjunctive tool for intraoperative rapid detection of brain tumors and demarcation of the tumor from the surrounding normal tissue. Measurements were performed on 29 excised tumor specimens from 29 patients. There were 21 instances of low-grade tumors and eight instances of high-grade tumors. Normal gray matter and white matter brain tissue specimens of four epilepsy patients were used as a control group. One low-grade and one high-grade tumor were misclassified as normal brain tissue. Of the low- and high-grade tumors, 20 out of 21 and 7 out of 8 were correctly classified by the ELSSS system, respectively. One normal white matter tissue margin was detected in a high-grade tumor, and three normal tissue margins were detected in three low-grade tumors using spectroscopic data analysis and confirmed by histopathology. The spectral slopes were shown to be positive for normal white matter brain tissue and negative for normal gray matter and tumor tissues. Our results indicate that signs of spectral slopes may enable the discrimination of brain tumors from surrounding normal white matter brain tissue with a sensitivity of 93% and specificity of 100%.


Subject(s)
Algorithms , Brain Neoplasms/diagnosis , Brain Neoplasms/surgery , Elasticity Imaging Techniques/methods , Spectrum Analysis/methods , Surgery, Computer-Assisted/methods , Feasibility Studies , Humans , Light , Reproducibility of Results , Scattering, Radiation , Sensitivity and Specificity
8.
Ann Anat ; 189(1): 75-8, 2007.
Article in English | MEDLINE | ID: mdl-17319612

ABSTRACT

During dissection of the retropubic region of a 55-year-old female cadaver, we encountered an angiolipoma located inside the obturator canal which was connected to the wall of the urinary bladder by a fibrous cord. The angiolipoma was supplied by a branch originating from the umbilical artery. Microscopically the benign soft tissue tumor was characterized by lobules of mature adipocytes and densely distributed networks of small and larger blood vessels, thus resembling typical histological features of an angiolipoma. Both the uncommon location of the angiolipoma and the abnormal branch of the umbilical artery entering the obturator canal should be taken into account during surgical procedures in this region, such as for orthopedic pelvic procedures, hernia repair or bladder/urethra-related interventions (e.g. transobturator tape, tension-free vaginal tape, colposuspension).


Subject(s)
Angiolipoma/pathology , Umbilical Arteries/pathology , Cadaver , Dissection , Female , Humans , Middle Aged
9.
J Reconstr Microsurg ; 22(8): 649-54, 2006 Nov.
Article in English | MEDLINE | ID: mdl-17136678

ABSTRACT

Although various administration routes of FK506 have been published, intrathecal administration of FK506 has not previously been reported in the literature. A daily dose of 0.05 mg/kg of FK506 was given (a small dose compared with those reported in the available literature). The authors used this small dose to obtain lower immunosuppression and neurotoxicity, and a higher axonal regeneration rate. A total number of 40 female Wistar rats were used and randomly divided into four groups: control, sham, FK506-treated, and vehicle-treated. Sciatic nerve regeneration was evaluated by walking track analysis, an electrostimulation test, and light microscopic evaluation. There was a statistically significant difference ( P < 0.05) between FK506-treated and vehicle-treated groups at the end of 6 weeks according to both the walking track analysis and the electrostimulation test. Comparing the stimulus thresholds of the sham and FK506-treated group, no significant difference ( P > 0.05) was observed. Evaluation of the data revealed that FK506 had a beneficial effect on sciatic nerve regeneration.


Subject(s)
Immunosuppressive Agents/administration & dosage , Nerve Regeneration/drug effects , Tacrolimus/administration & dosage , Animals , Axons/drug effects , Axons/physiology , Female , Injections, Spinal , Rats , Rats, Wistar , Sciatic Nerve/drug effects , Sciatic Nerve/injuries , Sciatic Nerve/metabolism , Transplantation, Homologous
10.
J Reconstr Microsurg ; 21(5): 307-12, 2005 Jul.
Article in English | MEDLINE | ID: mdl-15971165

ABSTRACT

Peripheral-nerve trauma has been a challenge to surgeons, with significant advances in the surgery of repair. Immobilization of the injured limb after repair has been the traditional method of treatment. Although peripheral-nerve regeneration has been studied extensively, the correlation between functional recovery and the immobilization period has not been well-documented. In the present study, the authors studied the effects of immobilization on axonal regeneration after sciatic crush injury. They found a detrimental effect of immobilization on the functional recovery.


Subject(s)
Axons/physiology , Nerve Regeneration , Restraint, Physical/adverse effects , Sciatic Nerve/injuries , Animals , Female , Rats , Rats, Wistar , Recovery of Function , Time Factors
SELECTION OF CITATIONS
SEARCH DETAIL
...