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3.
J Dermatol Case Rep ; 7(3): 88-92, 2013.
Article in English | MEDLINE | ID: mdl-24133563

ABSTRACT

BACKGROUND: The incidence of cutaneous melanoma is increasing worldwide and early diagnosis is essential since the prognosis is poor in advanced stages of disease. Dermoscopy emerged as an additional and important diagnostic procedure for the early diagnosis of cutaneous melanoma. MAIN OBSERVATION: We report a case of a 52-year-old man, who developed a pigmented lesion in the right pretibial region. Dermoscopy highly suggestive of melanoma. The initial histopathological evaluation suggested a benign lesion. Since dermoscopy was very suspicious, a more extensive histopathological study of the excised skin fragment was performed. This led to a change of diagnosis to a melanoma with partial regression. CONCLUSIONS: The present case shows that occasionally dermoscopy may be more informative for diagnosis of melanoma than an initial histopathology result.

4.
Skinmed ; 10(4): 228-31, 2012.
Article in English | MEDLINE | ID: mdl-23008940

ABSTRACT

A 56-year-old woman presented with a painless lesion on the inner aspect of her upper lip. The clinical differential diagnoses were oral syphilitic chancre, tuberculosis, histoplamosis, and neoplasia. A biopsy was performed, and the histopathologic diagnosis revealed an eosinophilic ulcer of the oral mucosa. Based on this case, we discuss the history, mechanisms of pathogenesis, clinical manifestations, histopathology, differential diagnosis, and therapy of eosinophilic ulcer of the oral mucosa.


Subject(s)
Eosinophilia , Oral Ulcer , Diagnosis, Differential , Eosinophilia/metabolism , Eosinophilia/pathology , Eosinophils/metabolism , Female , Humans , Immunohistochemistry , Middle Aged , Mouth Mucosa/metabolism , Mouth Mucosa/pathology , Oral Ulcer/metabolism , Oral Ulcer/pathology
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