1.
Farmakol Toksikol
; 49(4): 62-3, 1986.
Article
in Russian
| MEDLINE
| ID: mdl-3758331
ABSTRACT
It was demonstrated in experiments on various animal species that pyridoxal phosphate had low toxicity and easily penetrated across the skin barrier without producing general toxic, irritant and allergenic effects.
Subject(s)
Pyridoxal Phosphate/toxicity , Skin Absorption/drug effects , Administration, Topical , Animals , Guinea Pigs , Male , Mice , Pyridoxal Phosphate/metabolism , Rabbits , Rats , Skin/metabolism , Time Factors
2.
Vestn Dermatol Venerol
; (2): 49-52, 1986.
Article
in Russian
| MEDLINE
| ID: mdl-2939655
Subject(s)
Acne Vulgaris/drug therapy , Cosmetics , Pyridoxal Phosphate/administration & dosage , Administration, Topical , Adolescent , Adult , Humans , Male
3.
Farmakol Toksikol
; 48(6): 55-7, 1985.
Article
in Russian
| MEDLINE
| ID: mdl-4085632
ABSTRACT
In white rats with B6-avitaminosis, the B6-vitamin activity of pyridoxal-phosphate and of pyridoxine was studied in their epicutaneous and peroral application. It is revealed that pyridoxal-phosphate in epicutaneous application displays more activity than pyridoxine and pyridoxal-phosphate applied perorally. Pyridoxine in epicutaneous application does not reveal the B6-vitamin activity.