ABSTRACT
The article presents data on androgen levels in female patients with temporomandibular joint (TMJ) dysfunction of varying degree and class II malocclusion. The study revealed significant correlation between degenerative and inflammatory TMJ changes and androgens level in patients with stigmas of connective tissue dysplasia (p<0.05), probably due to indirect proinflammatory action of androgens as they stimulate inflammatory mediators expression.
Subject(s)
Androgens/blood , Malocclusion, Angle Class II/blood , Malocclusion, Angle Class II/pathology , Temporomandibular Joint Dysfunction Syndrome/blood , Temporomandibular Joint Dysfunction Syndrome/pathology , Temporomandibular Joint/pathology , Adult , Connective Tissue/pathology , Female , Humans , Inflammation/pathology , Magnetic Resonance Imaging , Male , Young AdultABSTRACT
Currently Temporomandibular joint (TMJ) dysfunction is a very highly discussed topic by both researchers and clinicians. the incidence of the of TMJ is dysfunctions still not very well established because of heterogeneity of the diagnostic criteria used by different authors. This article is dedicated to the analysis of basic theories of the etiology of the aforementioned pathology, including overview of main pathophysiological mechanisms of the TMJ, dysfunctions occlusive disorders in particular. The main problem being analyzed is the use and efficacy of the electronic axiography in successful diagnostic and therapy of the TMJ dysfunction.
