ABSTRACT
Despite the use of modern methods of prevention, at least 10% of patients operated on for ophthalmic indications not develop corneal erosion as the indirect complication of general anesthesia. OBJECTIVE: To reduce the number of ophthalmic complications of general anesthesia by prophylactic use of new mito- chondria-targeted antioxidants - Vizomitin (eye drops). MATERIALS AND METHODS: 70 patients, which was supposed to perform the average duration of operations under general anesthesia were randomized into 3 groups depending on the method specific (pharmacological) prevention of corneal erosions: (1) control (specic (pharmacological) prevention was not carried out), (2), using preparation "natural tear, and (3) "Vizomitin" preparation. Postoperative biomicroscopy was performed to assess the condition of the cornea, tear film stability was measured and the height of the tear meniscus. RESULTS: When using eye drops "Vizomitin" value is an indicator of stability of the tear film on the 3rd day after the operation more than in the control group of patients by 51% (p = 0.012) and patients groups, natural tear by 57% (p = 0.013). Surgical interventions performed under general anesthesia, leading to an increase in the number ofpatients with decreased tear meniscus height index of the control group with 4 to 7 patients (p = 0.30) in the group of natural tear from 3 to 11 patients (p = 0.008) . In the group with drug "Vizomitin" the number of such patients is reduced from 7 to 1 (p = 0.018). CONCLUSION: In the surgical procedures under general anesthesia eye drops "Vizomitin" effectively prevents the devel- opment of corneal erosion.
Subject(s)
Anesthesia, General/adverse effects , Antioxidants/therapeutic use , Benzalkonium Compounds/therapeutic use , Cornea/drug effects , Dry Eye Syndromes/prevention & control , Methylcellulose/therapeutic use , Mitochondria/drug effects , Plastoquinone/therapeutic use , Adult , Antioxidants/administration & dosage , Benzalkonium Compounds/administration & dosage , Cornea/pathology , Drug Combinations , Dry Eye Syndromes/etiology , Humans , Lubricant Eye Drops/administration & dosage , Lubricant Eye Drops/therapeutic use , Methylcellulose/administration & dosage , Middle Aged , Mitochondria/pathology , Plastoquinone/administration & dosage , Postoperative Complications , Treatment Outcome , Young AdultABSTRACT
Peculiarities of use of luminescent and semiconductor converters of X-radiation in radioscopy are examined. Characteristic features of X-ray devices (electro-optical transducers, X-ray vidicons, gas discharge and luminescent converters), based on the use of luminescent and semiconductor converters are comparatively analyzed. Estimation of X-ray image quality is given. Use of gas discharge and luminescent converters is found to be the most prospective for medical radioscopy. The aforementioned converters are distinguished by high dose sensitivity, simplicity of the construction and greater size of working field.
Subject(s)
Radiographic Image Enhancement/instrumentation , Semiconductors/standards , X-Ray Intensifying Screens/standards , Equipment Design , Quality Control , Radiation Dosage , Radiographic Image Enhancement/methods , Thermoluminescent Dosimetry/instrumentation , USSRABSTRACT
A digital memory and a control unit are described that along with the pulse X-ray TV diagnostic system enable reduction of the exposure dose in the course of X-ray examinations. Diagnostic capabilities of the system are improved due to possibility to view up four images at various examination angles at the display and to scale every image.
Subject(s)
Radiography/instrumentation , Television , Humans , Radiation DosageABSTRACT
Main features of digital processing of X-ray images are analysed. A preferable algorithm of the image synthesis is built. The contrast control of visual images has been shown to result in improved informativity of roentgenograms.
