[Radionuclide methods for diagnostics of non-rheumatic myocarditis and postmyocarditic cardiosclerosis].

We compared the results of comprehensive scintigraphic examination of 35 patients with suspected myocarditis and the data of clinical, immunological, laboratory and instrumental studies. The patients were divided into 3 groups. Group 1 included 11 patients with preliminary diagnosis of acute myocarditis, group 2--11 patients with chronic myocarditis, group 3--13 patients with postmyocarditic cardiosclerosis. All patients were tested for antimyocardial antibodies, underwent 99mTc-HMPAO-labeled leukocyte and perfusion scintiography of myocardium. The study did not reveal significant differences between the three groups as regards the results of laboratory and instrumental studies. Elevated titers of antimyocardial antibodies were found in 70% of the patients in group 1, 100% in group 2, and 46% in group 3. Patients with chronic myocarditis had the highest titers of antibodies. Pathological accumulation of 99mTc-HMPAO-labeled leukocytes in myocardium was documented in 36.4 and 81.8% of the patients of groups 1 and 2 respectively. They were absent in the heart of group 3 patients. Disturbed myocardial perfusion was recorded in 45.5, 81.8 and 84.6% in groups 1, 2 and 3 respectively. The magnitude of accumulation of leukocytes was not significantly different between the groups. Results of the study suggest rather high specificity of radionuclide techniques for diagnostics of inflammatory lesions in myocardium. However, further studies are needed to confirm their sensitivity and accuracy.

[Data on the X-sex chromatin content and cytokaryometric characteristics of the cells of human amniotic fluid and of provisory and definitive organs]. / Nekotorye dannye k soderzhaniiu X-polovogo khromatina i tsitokariometricheskoi kharakteristike kletok amnioticheskoi zhidkosti, provizornykh i definitivnykh organov cheloveka.

In different zones of the aminion there is a different amount of cells with X-chromatin containing nuclei. Four types among most common cells of amniotic fluid are described. The sizes of cells, nuclei and nucleoli in different zones of the amnion, amniotic fluid, fetal cheeck mucous and fetal urina are compared. The material taken by biopsy from provisory organs is suggested to be used for cytogenetic studies.

[State of the blood coagulation and anticoagulation system in women taking oral contraceptives]. / Sostoianie svertyvaiushchei i protivosvertyvaiushchei sistemy krovi u zhenshchin pri prieme oral'nykh kontratseptivov.

PIP: It is known that a prolonged use of combinations of nortestosterone and estrogens may cause some side effects among which modifications in the blood coagulation and anticoagulation systems. A study was done on 100 women divided in 2 groups. The 1st group consisted of 70 women who were taking estrogeno-gestagen combinations: 37 for dysfunction of the ovaries, 16 for endometriosis, 1 for dysmenorrhea, 1 for climacteric syndrome and 15 for contraceptive purposes. 22 women had taken the oral contraceptives for 3 months, 16 for 4-6 months, 13 for 7-9 months, 4 for 1 year and 15 for over 1 year. The 2nd group consisted of 30 women among which 8 had ovarian dysfunctions, 8 endometriosis, 4 climacteric syndrome, 2 dysmenorrhea; 8 were healthy. Blood analyses were performed during the treatment in women of the 1st group and before the beginning of the treatment for the women from the 2nd group. Thromboelastograms and coagulograms revealed an increased blood coagulating activity in the women from the 1st group, who had been taking contraceptive agents. (Summary in ENG).^ieng