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1.
Article in Russian | MEDLINE | ID: mdl-3705750

ABSTRACT

In acute experiments on kittens the process of formation of asymmetry of transcallosal responses (TCR) was studied in multiple leads from symmetrical points of the parietal cortex. By the early positive-negative TCR complex, vanishing as a result of callosotomy, predominance of positive components in the right hemisphere was found in 2-7 days kittens, whereas in 8-24 days animals the left hemisphere dominated by both phases of responses. By the late TCR component preserved after section of the callosal body, left-hemispheric asymmetry was found in the elder group of kittens; it was absent in the younger animals. TCR asymmetry in the parietal cortex depended on the sex of the animals. With their age its inversion and enhancement took place. This process is based on the increase of TCR amplitude in the left hemisphere, with no increase in the right hemisphere.


Subject(s)
Aging , Corpus Callosum/physiology , Dominance, Cerebral/physiology , Parietal Lobe/physiology , Animals , Brain Mapping , Cats , Electric Stimulation , Evoked Potentials , Female , Male , Sex Characteristics
2.
Article in Russian | MEDLINE | ID: mdl-3920844

ABSTRACT

The qualitative differences in the affinity of concanavalin A (Con A), wheat-germ agglutinin (WGA) and Phaseolus vulgaris lectin to the surface of 10 microbial strains inducing various diseases in humans and agricultural animals have been demonstrated by means of the indirect immunofluorescence tests. Enterobacteria, Coxiella burnetii and Bacillus anthracis have been found to possess pronounced affinity to Con A and WGA, while Rickettsia prowazekii, Francisella tularensis and Brucella abortus, as well as Treponema pallidum, have proved to be resistant to lectins. WGA has been found to bind specifically to Brucella abortus and Treponema pallidum. Con A and WGA are seemingly suitable for use in the preliminary test for the total capacity of lectin receptors to come in contact with biological macromolecules.


Subject(s)
Bacteria/drug effects , Fluoresceins/pharmacology , Fluorescent Dyes/pharmacology , Lectins/pharmacology , Thiocyanates/pharmacology , Animals , Bacteria/isolation & purification , Concanavalin A/pharmacology , Fluorescein-5-isothiocyanate , Fluorescent Antibody Technique , Immunization , Immunization, Secondary , Phytohemagglutinins/pharmacology , Rabbits , Wheat Germ Agglutinins
3.
Biull Eksp Biol Med ; 92(7): 60-2, 1981 Jul.
Article in Russian | MEDLINE | ID: mdl-6170360

ABSTRACT

Active antisera containing antibodies to deproteinized DNA preparations of mouse normal and leukemic tissues have been obtained. Examination of antisera by the quantitative complement fixation test with the corresponding test antigens has demonstrated immunological specificity of DNA preparations isolated from the organs of mice with leukemia induced by oncornaviruses. The DNA specificity in question is inherent not only in the native but also in the thermodenatured molecule of DNA.


Subject(s)
DNA, Neoplasm/immunology , Leukemia, Experimental/immunology , Animals , Complement Fixation Tests , Epitopes/analysis , Friend murine leukemia virus , Mice , Nucleic Acid Conformation , Nucleic Acid Denaturation , Rauscher Virus , Spleen
4.
Genetika ; 13(3): 439-50, 1977.
Article in Russian | MEDLINE | ID: mdl-892432

ABSTRACT

Coefficients of heritability of lipid, carbohydrate and protein-nitrous blood metabolites were studied through comparison of mothers and their daughters at different age periods (6, 9, 12, 15, 18 months and the 1st lactation) and seasons. The highest and most statistically significant are heritability coefficients of triglycerides, phospholipids, cholesterin, total lipids; coefficients of acetic acid, 3-hydroxybutyric acid, acetone and acetylacetic acid and blood glucose are lower. The highest coefficients of heritability among protein-nitrous metabolites are those of globulins; coefficients of albumins, total protein, blood amino nitrogen are lower. Heritability coefficients of blood metabolites, except albumins, globulins and glucose are stable enough at different age periods. No pronounced season differences are observed. The presence of high and statistically significant heritability coefficients of a number of blood metabolites, their age and season stability indicate the possibility of using these metabolites as additional tests in selection of dairy cattle.


Subject(s)
Blood Glucose , Blood Proteins , Cattle/blood , Age Factors , Animals , Female , Lipids/blood , Seasons
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