Exploring the Prevalence and Resistance of Campylobacter in Urban Bird Populations.

The increasing urbanization of ecosystems has had a significant impact on wildlife over the last few years. Species that find an unlimited supply of food and shelter in urban areas have thrived under human presence. Wild birds have been identified as amplifying hosts and reservoirs of Campylobacter worldwide, but the information about its transmission and epidemiology is still limited. This study assessed the prevalence of Campylobacter in 137 urban birds admitted at a wildlife rescue center, with 18.8% of individuals showing positive. C. jejuni was the most frequent species (82.6%), followed by C. coli and C. lari (4.3% each). The order Passeriformes (33.3%) showed significant higher presence of Campylobacter when compared to orders Columbiformes (0%) and Ciconiiformes (17.6%), as well as in samples collected during the summer season (31.9%), from omnivorous species (36.8%) and young individuals (26.8%). Globally, Campylobacter displayed a remarkable resistance to ciprofloxacin (70.6%), tetracycline (64.7%), and nalidixic acid (52.9%). In contrast, resistance to streptomycin was low (5.8%), and all the isolates showed susceptibility to erythromycin and gentamycin. The results underline the importance of urban birds as reservoirs of thermophilic antimicrobial-resistant Campylobacter and contribute to enhancing the knowledge of its distribution in urban and peri-urban ecosystems.

Addressing Challenges in Wildlife Rehabilitation: Antimicrobial-Resistant Bacteria from Wounds and Fractures in Wild Birds.

Injuries and bone fractures are the most frequent causes of admission at wildlife rescue centers. Wild birds are more susceptible to open fractures due to their anatomical structure, which can lead to osteomyelitis and necrosis. Antibiotic therapy in these cases is indispensable, but the increase of antimicrobial-resistant isolates in wildlife has become a significant concern in recent years. In this context, the likelihood of antibiotic failure and death of animals with infectious issues is high. This study aimed to isolate, identify, and assess the antimicrobial resistance pattern of bacteria in wounds and open fractures in wild birds. To this end, injured birds admitted to a wildlife rescue center were sampled, and bacterial isolation and identification were performed. Then, antimicrobial susceptibility testing was assessed according to the disk diffusion method. In total, 36 isolates were obtained from 26 different birds. The genera detected were Staphylococcus spp. (63.8%), Escherichia (13.9%), Bacillus (11.1%), Streptococcus (8.3%), and Micrococcus (2.8%). Among Staphylococcus isolates, S. lentus and S. aureus were the most frequent species. Antimicrobial resistance was detected in 82.6% of the isolates, among which clindamycin resistance stood out, and 31.6% of resistant isolates were considered multidrug-resistant. Results from this study highlight the escalating scope of antimicrobial resistance in wildlife. This level of resistance poses a dual concern for wildlife: firstly, the risk of therapeutic failure in species of significant environmental value, and, secondly, the circulation of resistant bacteria in ecosystems.

A Four-Year Survey of Hemoparasites from Nocturnal Raptors (Strigiformes) Confirms a Relation between Leucocytozoon and Low Hematocrit and Body Condition Scores of Parasitized Birds.

Most hemoparasites hosted by wild birds appear to be harmless, but most of the blood parasite studies in avian wildlife are mainly focused on passerines or migratory species. This study aimed to assess the occurrence of blood parasites in nocturnal raptors (Strigiformes order) and their effect on hematological parameters. A total of 134 blood samples were collected during a four-year period for hematological analysis and hemoparasite detection and quantification by microscopical examination of the samples. Overall, the occurrence of hemoparasites was 35.1%, with Leucocytozoon being the most frequently detected (32.1%), followed by Haemoproteus (11.2%), Trypanosoma and Plasmodium (2.2% each). Among the different bird species, the Eurasian eagle-owl (Bubo bubo) showed the highest blood parasite positivity (94.7%). In barn owls, the positive birds displayed a lower hematocrit measurement and body condition score than the non-parasitized ones (p = 0.007 and p = 0.005, respectively), especially those parasitized by Leucocytozoon. Moreover, the analysis of the magnitude of this association revealed that the presence of hemoparasites is five times more frequent in barn owls with a 2/5 body condition score. Despite the host-parasite coevolution in Strigiformes, our results show a correlation between the presence of hemoparasites and some health parameters, including blood parameters.

Antimicrobial Resistant Salmonella in Chelonians: Assessing Its Potential Risk in Zoological Institutions in Spain.

Salmonella is mostly noted as a food-borne pathogen, but contact with chelonians has also been reported as a source of infection. Moreover, high levels of antimicrobial resistance (AMR) have been reported in Salmonella isolated from wild and captive reptiles. The aim of this study was to assess the occurrence of Salmonella AMR carriage by chelonians admitted to two zoological institutions in Spain, characterizing the isolates to assess the Salmonella AMR epidemiology in wildlife. To this end, 152 chelonians from nine species were sampled upon their arrival at the zoological nuclei. Salmonella identification was based on ISO 6579-1:2017 (Annex D), isolates were serotyped and their AMR analysed according to the EU Decision 2013/652. Moreover, the genetic relationship of the isolates was assessed by pulsed-field gel electrophoresis (PFGE). Results showed 19% (29/152) of the chelonians positive to Salmonella, all of them tortoises. For all isolates, 69% (20/29) were resistant and 34% (10/29) multidrug-resistant (MDR) strains. PFGE clustered isolates according to the serovar, confirming a low genetic diversity. In conclusion, this study shows a high presence of MDR Salmonella strains in tortoises at their entry into zoological nuclei. This condition highlights the need to establish Salmonella detection protocols for the entry of animals into these centres.

Mechanical Valve Thrombosis Secondary to Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Case Report.

Although the association of coronavirus disease 2019 (COVID-19) and thromboembolic disease is well known, cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and mechanical valve thrombosis have not been described enough. Mechanical valve thrombosis is a medical emergency that is associated with a great impact on patients' morbidity and mortality. Here, we report a case of a patient with mechanical valve thrombosis secondary to SARS-CoV-2 infections that required valve replacement with satisfactory postoperative recovery. A 52-year old female patient was presented with a previously implanted mechanical prosthesis (type - St. Jude Medical 29 mm; St. Paul, MN: St. Jude Medical, Inc.) eight years ago due to rheumatic fever, under anticoagulation with warfarin and valvular atrial fibrillation (permanent), congenital single kidney (glomerular filtration rate {GFR}: 89.9 mL/min), and hypothyroidism. She was admitted to the hospital with a high level of complexity due to respiratory difficulty and generalized edematous syndrome, and a reverse transcription-polymerase chain reaction (RT-PCR) confirmed COVID-19 infection (20 days before admission); the patient was anticoagulated with warfarin (international normalized ratio {INR} at admission was 2.63 seconds). As per protocol, a CT-chest scan tomography was performed and showed organized pneumonia in the right apical lobe. We performed a transesophageal echocardiogram, which showed a thrombus (20 x 15 x 20 mm) in the lateral disc of the mechanical prosthesis, restricting its mobility. The patient presented signs of hypoperfusion (lactate levels: 4 mmol/L; urine per hour: 1 cc/kg) with associated low cardiac output syndrome, requiring double vasopressor support at the maximum dose (achieving a mean arterial pressure of 72 mmHg) due to the clinical condition and the large size of the thrombus, the cardiovascular surgeon, in agreement with the family, decides to carry out emergency valve replacement surgery with replacement of a mechanical prosthesis replacement (St. Jude No. 29; St. Paul, MN: St. Jude Medical, Inc.). The patient presented a satisfactory postoperative recovery, achieving INR goals, with subsequent discharge and follow-up at two months with transthoracic ultrasound, where normofunctional mitral prosthesis was demonstrated, without evidence of thrombi or intracavitary masses. Mechanical mitral valve thrombosis, secondary to SARS-CoV-2 infection is a serious complication with poor prognosis that requires a high rate of suspicion, and timely diagnostic aids are essential to confirm the diagnosis. Managing this issue should be interdisciplinary and individualized considering the clinical condition of the patient and the associated comorbidities.

Prevalence and antimicrobial resistance of Campylobacter from wild birds of prey in Spain.

Wild birds have been identified as a relevant reservoir of Campylobacter spp., therefore, a potential source of infection in humans and domestic animals. The objective of this study was to determine the occurrence of Campylobacter spp. on birds of prey in Spain. In addition, antibiotic resistance profiles of the isolates were evaluated. A total of 689 specimens of 28 raptor species were analyzed, with a resulting individual prevalence of 7.5%. C. jejuni was the most frequently isolated species (88.5%), followed by C. coli and C. lari (3.8% each). The occurrence of Campylobacter was significantly higher (p < 0.05) in nocturnal birds of prey (15.3%), in spring season (12.2%) and in carnivorous species (9.4%). Isolates displayed a remarkable resistance to nalidixic acid (69.9%), ciprofloxacin (69.9%), and tetracycline (55.6%), and a low resistance to streptomycin (6.7%). Our findings highlight the importance of birds of prey as reservoirs of Campylobacter strains and their significant role as carriers of antimicrobial resistance.

Taphonomy of experimental burials in Taphos-m: The role of fungi.

BACKGROUND: The fungi present in the decaying remains enable a better understanding of the processes of decomposition after death. There are not many studies about fungi on decaying bodies and it is not known which fungal sampling methods are effective. AIMS: The main objective of this study was to find the best method for sampling fungi in carcasses, prove the effectiveness of this method and identify the fungal colonies in animal carcasses from experimental burials. METHODS: Samples from 13 carcasses of Sus scrofa domestica, from the experimental project Taphos-m, were taken with different materials: spatula, sterile swabs and RODAC contact plates. RESULTS: RODAC contact plates with the RBA culture medium showed higher proliferation of fungal colonies. Thirty genera of fungi were isolated from different substrates (bone, tissue, lime). Most of the fungi genera or groups identified have been described before in the literature, but the substrates they came from were different in some cases. CONCLUSIONS: Sampling with RODAC contact plates was found to be the most effective method, as it provides a nutritional culture medium that may allow growth since the moment of sampling. Fungi colonies grew better in RBA culture medium because bacterial growth is inhibited. Most of the observed fungi are related to the environment but some others have been found related to decomposing bodies for the first time.

Características clínicas, bioquímicas y complicaciones de los pacientes sometidos a la cirugía bariátrica con 18 meses de seguimiento en un hospital de alta complejidad / Clinical, biochemical characteristics and complications in bariatric surgery patients in 18 months of follow-up in a highly complex hospital

RESUMEN Objetivo: el objetivo de este estudio fue describir los cambios en las características clínicas, bioquímicas y las complicaciones de los pacientes sometidos a la cirugía bariátrica en 18 meses de seguimiento en un hospital de alta complejidad entre 2012 y 2016. Métodos: se realizó un estudio descriptivo, retrospectivo para evaluar las variables clínicas y bioquímicas, antes y después de la realización de la cirugía bariátrica (el bypass gástrico o manga gástrica). Resultados: se estudiaron 59 pacientes, el 89,8 % fueron mujeres, con edad promedio de 41,8 ± 10,8 años. El 76,3 % se sometieron a bypass gástrico y el 23,7 % a manga gástrica. La media del porcentaje de peso perdido a los 18 meses fue de 81 % ± 22. Se presentó una reducción significativa de la circunferencia abdominal. El 100 % de los pacientes experimentaron cambios en las multimorbilidades. Conclusión: se encontró una disminución significativa del porcentaje de exceso del índice de masa corporal, además se observó un cambio en las comorbilidades y modificación en los biomarcadores. No se presentó mortalidad a los 18 meses postquirúrgicos.

SUMMARY Objective: To determine the clinical and biochemical characteristics, as well as the complications of bariatric surgery in 18 months of follow-up in a highly complex hospital, between 2012 and 2016. Methods: A descriptive, retrospective study was performed in patients undergoing bariatric surgery (gastric by-pass or gastric sleeve), where the clinical and biochemical characteristics, as well as the complications and post-intervention changes were evaluated in a before-after analysis. Results: Fifty nine patients were studied, 89.8 % were women, with an average age of 41.8 ± 10,8. The 76,3 % underwent gastric bypass and 23.7 % gastric sleeve. The mean percentage of weight lost at 18 months was 81 % ± 22. There was a significant reduction in abdominal circumference. 100 % of patients experienced changes in multimorbidities. Conclusion: We found a significant decrease in the percentage of body mass index. In addition, a change in comorbidities and modification in biomarkers was observed. There was no post-operative mortality 18 months after surgery.

Comparación de los efectos tafonómicos observados en dos estructuras funerarias de espacio vacío / The taphonomic effects comparison in two empty space burial structures

Introducción. La tafonomía ayuda a entender las cuestiones relacionadas con las modificaciones post mortem de los restos cadavéricos en los campos de la paleontología, la arqueología y la antropología forense. Por ello, el objetivo principal del proyecto experimental Taphos-m es generar un corpus en tafonomía que permita comprender qué agentes y procesos tafonómicos son los responsables de los efectos observados en diferentes contextos. Material y métodos. Pasados 3 años y medio desde su inhumación, se ha valorado el estado cadavérico de 2 cuerpos de Sus scrofa domestica enterrados en 2 estructuras vacías de características constructivas distintas, así como la distribución espacial que presentaban los elementos anatómicos. En caso de esqueletización, también se describe el estado de la superficie cortical de los huesos y la eventual fragmentación ósea. También se han llevado a cabo analíticas complementarias, como análisis histológico y patológico. Resultados. Los restos del animal enterrado en la tumba de piedra se encontraron en estado desecado, mientras que los restos inhumados en la tumba de tejas planas estaban prácticamente esqueletizados. Se observaron diferencias en el análisis de los efectos tafonómicos, sobre todo en relación con la distribución espacial de los elementos anatómicos, vinculados con la presencia de sedimento y el estado cadavérico. La lesión que presentaba uno de los animales en la extremidad trasera podría influir en el mantenimiento de la articulación anatómica. Conclusiones. Los datos meteorológicos del momento de la inhumación y las características de la tumba son variables que determinan la evolución y el estado cadavérico de los restos, pero no son las únicas, ya que las lesiones pueden suponer diferencias en la distribución espacial de los restos óseos y articulaciones anatómicas (AU)

Introduction. Taphonomy helps to understand the issues related to changes of the cadaveric remains in the frame of palaeontology and archaeology as well as in the frame of forensic anthropology. The first objective of the experimental project Taphos-m was to generate a corpus of information on taphonomy to know what taphonomic agents and process could be responsible for the observable effects in field. Materials and methods. The cadaveric state of Sus scrofa domestica remains and the spatial distribution of the anatomical elements has been described. In the case of skeletonization, the state of the cortical surface and fragmentation of the bones was evaluated too. Also the pathological and histological analysis has been observed. Results. The animal remains buried in the stone tomb were in dried state, while the remains buried in the tile tomb were skeletonized. There were differences in the observable taphonomic effects, particularly in the spatial distribution of the anatomical elements. The lesion in the leg of one animal could be responsible of the maintenance of anatomic articulation. Conclusions. Meteorological data during inhumation and the tomb characteristics are variables that determine the evolution and condition of the remains, but they are not the only ones: the pathological lesions may involve differences in the spatial distribution of the bones and anatomical articulations (AU)

Foveal vs. parafoveal processing in anxiety: broadened spatial attention for threat words

El presente estudio investiga el procesamiento parafoveal de palabras de amenaza, de contenido emocional positivo, y neutras, en función de diferencias individuales en rasgo de ansiedad. En una tarea de decision léxica, palabras estímulo (prime) fueron presentadas durante 150 ms parafovealmente (alejadas 2.2° del punto de fijación; Experimento 1) o fovealmente (en el punto de fijación; Experimento 3), seguidas por una palabra de prueba (probe), o bien las palabras probe fueron presentadas solas (sin prime; Experimento 2). Los resultados mostraron que las prime parafoveales de amenzaza facilitaron las respuestas a las probe de amenaza en los participantes con ansiedad elevada, en comparación con las palabras positivas y las neutras, y con los participantes con ansiedad baja. En contraste, cuando las prime fueron presentadas fovealmente, no se produjeron diferencias en los niveles básicos de activación de las probe aisladas (línea base de accesibilidad), ni tampoco en los umbrales de activación por el prime, en función del contenido emocional de las palabras o de la ansiedad de los participantes. Esto revela un sesgo en la atención encubierta a estímulos amenazantes en las personas con ansiedad elevada(AU)

We investigated the processing of threat-related, positive, and neutral words in parafoveal and in foveal vision as a function of individual differences in trait anxiety. In a lexical-decision task, word primes were presented for 150 ms either parafoveally (2.2° away from fixation; Experiment 1) or foveally (at fixation; Experiment 3) followed by a probe word; or a foveal probe word was presented alone (with no prime; Experiment 2). Results showed that parafoveal prime threat words facilitated responses to probe threat words for high-anxiety individuals, in comparison with neutral and positive words, and relative to low-anxiety individuals. In contrast, when the words were presented foveally, there were no differences in resting activation level (i.e., accessibility to single word meanings) or firing thresholds (i.e., foveal priming) as a function of emotional content and anxiety. This reveals a covert attention bias towards threat stimuli in anxiety(AU)

How spatial attention and attentional resources influence the processing of emotional visual scenes.

Pleasant, neutral, or unpleasant pictures appeared for 150 ms in either peripheral or foveal vision, with or without a concurrent foveal load task. Participants indicated whether the visual scene in the picture was or was not pleasant, or was or was not unpleasant. The manipulation of picture location (foveal vs. peripheral) aimed to tap spatial attention, while the perceptual load task was used to manipulate the availability of attentional resources. Results showed that emotional valence was discriminated above the chance level even in the attentionally-constrained conditions (peripheral presentation combined with perceptual load). Nevertheless, valence encoding depended on both attentional mechanisms, as indicated by reductions in accuracy and by slowed reaction times in valence identification when attention was allocated elsewhere, relative to when the scene appeared at fixation and when there was no concurrent task. This indicates that emotional processing requires attention.

Enhanced processing of emotional gist in peripheral vision.

Emotional (pleasant or unpleasant) and neutral scenes were presented foveally (at fixation) or peripherally (5.2 degrees away from fixation) as primes for 150 ms. The prime was followed by a mask and a centrally presented probe scene for recognition. The probe was either identical in specific content (i.e., same people and objects) to the prime, or it was related to the prime in general content and affective valence. The probe was always different from the prime in color, size, and spatial orientation. Results showed an interaction between prime location and emotional valence for the recognition hit rate, but also for the false alarm rate and correct rejection times. There were no differences as a function of emotional valence in the foveal display condition. In contrast, in the peripheral display condition both hit and false alarm rates were higher and correct rejection times were longer for emotional than for neutral scenes. It is concluded that emotional gist, or a coarse affective impression, is extracted from emotional scenes in peripheral vision, which then leads to confuse them with others of related affective valence. The underlying neurophysiological mechanisms are discussed. An alternative explanation based on the physical characteristics of the scene images was ruled out.

Enhanced Processing of Emotional Gist in Peripheral Vision

Emotional (pleasant or unpleasant) and neutral scenes were presented foveally (at fixation) or peripherally (5.2° away from fixation) as primes for 150 ms. The prime was followed by a mask and a centrally presented probe scene for recognition. The probe was either identical in specific content (i.e., same people and objects) to the prime, or it was related to the prime in general content and affective valence. The probe was always different from the prime in color, size, and spatial orientation. Results showed an interaction between prime location and emotional valence for the recognition hit rate, but also for the false alarm rate and correct rejection times.There were no differences as a function of emotional valence in the foveal display condition. In contrast, in the peripheral display condition both hit and false alarm rates were higher and correct rejection times were longer for emotional than for neutral scenes. It is concluded that emotional gist, or a coarse affective impression, is extracted from emotional scenes in peripheral vision, which then leads to confuse them with others of related affective valence. The underlying neurophysiological mechanisms are discussed. An alternative explanation based on the physicalcharacteristics of the scene images was ruled out (AU)

En un paradigma de reconocimiento se presentaron fotografías-estímulo (prime) de escenas emocionales y neutras durante 150 ms cada una, bien fovealmente (en el centro de fijación visual) o periféricamente (a 5.2° de separación), seguidas por una máscara y una fotografía de prueba (probe). La fotografía prime y la probe podían ser idénticas en contenido específico (las mismas personas y objetos) o únicamente relacionadas en su contenido general y valencia emocional (agradables, desagradables, o neutras). Los resultados mostraron un efecto interactivo de la ubicación espacial y la valencia emocional sobre la tasa de aciertos, pero también la de falsas alarmas y el tiempo de rechazos correctos: No hubo diferencias en estas variables en función de la valencia emocional en la ubicación foveal; en cambio, en la periférica, tanto los aciertos como las falsas alarmas fueron más frecuentes, y el tiempo de los rechazos correctos fue más lento, para las escenas de contenido emocional que las neutras. Los autores concluyen que las personas obtienen una impresión genérica de la valencia afectiva de los estímulos pictóricos en visión periférica, que lleva a confundir las escenas con otras de similar valencia afectiva. Se examinan los mecanismos neurofisiológicos involucrados en este efecto de percepción emocional periférica. Se rechaza la hipótesis de que los efectos del contenido emocional de las imágenes sean debidos a diferencias en las propiedades físicas (AU)

Regulación de la temperatura del recién nacido después del baño / Temperature regulation of the newborn following bath

Este estudio se realizó en una Unidad de Recién Nacidos y tiene como propósito identificar los cambios significativos en la temperatura corporal del recién nacido después del baño de acuerdo con diferentes temperaturas ambientales. Participaron 15 recién nacidos con pesos entre 2000 y 4000 gramos, hospitalizados en el área de cunas, a quienes se les realizó baño diario durante cuatro días consecutivos en un horario previamente establecido y después se controló la temperatura central y del ambiente en periodos predeterminados. Los resultados muestran que no hay diferencias significativas entre las cifras halladas en la mañana y en la noche. Al evaluar el cambio de la temperatura del recién nacido, durante el tiempo de observación (0min a 60min), se encontró, a los 5 minutos del baño, un descenso de la temperatura estadísticamente significativo (P<0,01), rangos: 27 C- 36,8 C, temperatura media: 33,47 C (DE=5). Conclusión: la temperatura ambiente sí influye en la termorregulación de los recién nacidos después del baño

Desarrollo de ambientes virtuales para la distracción de niños entre los 4 y 6 años de edad / Development of virtual distraction environments for children between 4 and 6 years old

El proyecto “Desarrollo de Ambientes Virtuales para producir distracción en niños de 4 a 6 años de edad que requieren tratamiento odontológico” tuvo como objetivo desarrollar una herramienta para el manejo de la conducta del paciente pediátrico utilizando la tecnología de la Realidad Virtual. Para tal efecto se desarrollo un ambiente virtual utilizando como lenguaje de programación VRLM – Virtual Reality Modeling Lenguaje el cual exige como sistema operativo de aplicación el programa Windows XP, y como hardware mínimo necesario la utilización del procesador Pentium III de 1 Ghz, 256 Megabytes de memoria RAM y 50 Megabytes de espacio en disco. Se diseñaron y elaboraron ambientes virtuales por medio de un trabajo multidisciplinario entre odontólogos, psicólogos e ingenieros de sistemas, específicamente diseñados para permitir la relajación del niño y poder así disminuir su ansiedad y miedo frente al tratamiento odontológico. Dicho ambiente consiente de tres espacios virtuales conjugados dentro de un mundo de ambientación consistente de una casa, con una sala, un comedor y un patio; un mundo de objetos súper puestos en una habitación de plantas y un mundo de reconocimiento de objetos compuestos por una habitación de juguetes y otra de cuentos. Esta etapa tuvo como meta, desarrollar el ambiente virtual que será aplicado clínicamente en una consulta odontológica...

Amiloidosis laríngea: presentación de un caso / Laryngeal amyloidosis: one case

La amiloidosis es una enfermedad poco común, caracterizada por tener depósitos de agregados fibrilares de inmunoglobulinas monoclonales de cadenas ligeras en órganos vitales, puede ser localizada o generalizada, primaria o secundaria. Pueden estar involucrados múltiples órganos. En cabeza y cuello es una entidad muy rara y casi siempre se presenta en su formal localizada en el 12 al 90 por ciento de los casos, siendo el sitio más frecuente de presentación la laringe. El presente artículo expone el caso de una paciente femenina de 62 años de edad con historia de disfonía de un año de evolución. La exploración física sólo mostró lesiones rosáceas de aspecto rugoso en laringe, predominando en petíolo, bandas ventriculares y comisura anterior. Se le realizó microlaringoscopia directa con resección de las lesiones y toma de biopsia de las mismas, reportándose el estudio histopatológico como amiloidosis laríngea. Se descartó amiloidosis sistémica, ya que todos los estudios realizados fueron negativos. Se presenta una revisión de la literatura sobre los aspectos clínicos, histopatológicos, diagnósticos y terapéuticos de la amiloidosis laríngea

Pólipo osificante nasal. Caso clínico / Ossoficant nasal polypo. Case report

Se reporta el caso de una paciente femenino de 63 años de edad con tumoración en fosa nasal izquierda de 6 años de evolución, acompañada de obstrucción nasal ipsilateral desde su inicio. En la endoscopía se observó tumoración en fosa nasal izquierda dependiente de cola de cornete inferior que obstruía coana ipsilateral. En la tomografía computada se observó crecimiento heterogéneo dependiente de cola de cornete inferior izquierdo, con zona central de mayor densidad. Se realizó excisión completa de la tumoración por vía endoscópica, reportándose histopatológicamente como pólipo nasal con osificación central

Neurinoma del acústico. Presentación de un caso / Acoustic neuroma. A case report

Los neurinomas del acústico corresponden a los tumores benignos más frecuentes del ángulo pontocerebeloso. Son lesiones de lento crecimiento originados en las células de Schwann del nervio vestibular, que se manifiestan generalmente con síntomas cocleares y vestibulares. Presentamos el caso de una paciente del sexo femenino con historia de pérdida auditiva y tinitus izquierdo acompañados de vértigo. La exploración física sólo mostró pruebas de diapasones con Weber lateralizado a la derecha y Rinne positivo débil izquierdo. Los estudios iniciales de gabinete mostraron alteraciones sugestivas de lesión retrococlear consistente en hipoacusia sensorineural izquierda media a profunda, pobre discriminación fonémica, ausencia de reflejo estapedial, hipoexcitabilidad vestibular bilateral de predominio izquierdo, alargamiento de la latencia de la onda V e intervalos interonda I-III, III-V y I-V de los potenciales auditivos evocados del tallo cerebral. En los estudios de tomografía computada y resonancia magnética se observó un tumor dentro del conducto auditivo interno por lo que se efectuó la resección por vía translaberíntica con diagnóstico histopatológico de neurinoma del acústico. Se discute el caso y se compara con los reportes de la literatura