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Cell Host Microbe ; 32(5): 623-624, 2024 May 08.
Article in English | MEDLINE | ID: mdl-38723597

ABSTRACT

Common nutrients in our diet often affect our health through unexpected mechanisms. In a recent issue of Nature, Scott et al. show gut microbes convert dietary tryptophan into metabolites activating intestinal dopamine receptors, which can block attachment of bacterial pathogens to host cells.


Subject(s)
Dopamine , Gastrointestinal Microbiome , Gastrointestinal Microbiome/physiology , Dopamine/metabolism , Humans , Receptors, Dopamine/metabolism , Animals , Tryptophan/metabolism , Gastrointestinal Tract/microbiology , Gastrointestinal Tract/metabolism , Bacteria/metabolism , Host-Pathogen Interactions , Bacterial Adhesion
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