[The influence of the low-frequency laser radiation on microcirculatory disorders in the patients presenting with chronic viral hepatitis].

AIM: The objective of the present study was to elucidate the character of microcirculatory disorders in the patients presenting with chronic viral hepatitis and to evaluate the possibilities for the correction of the associated disorders with the use of laser irradiation. Material and methods. All the patients were divided into three groups. Group 1 was comprised of 30 patients who were treated by means of traditional medicamental therapy alone; they served as controls. Group 2 consisted of 45 patients treated by intravenous laser irradiation in addition to traditional medicamental therapy. The patients of group 3 (n=45) received a course of laser skin treatment. The state of microcirculation was assessed by the laser Doppler flowmetry (LDF) technique with the help of a LAKK-02 apparatus (<> Research and Manufacturing Complex, Moscow, Russia). RESULTS: The study has demonstrated heterogeneity of the types of microcirculation with the statistically significant increase in the frequency of its pathological cases. All the patients treated with the use of low-intensity laser therapy exhibited a significant improvement of the blood flow characteristics regardless of the initial hemodynamic type of microcirculation. CONCLUSION: It is concluded that the application of laser irradiation as a component of the combined treatment of the patients presenting with chronic viral hepatitis facilitates correction of microcirculatory disorders.

[[ENDOTHELIAL DYSFUNCTION AND ITS LOW-LEVEL LASER THERAPY CORRECTION IN PATIENTS WITH CHRONIC VIRAL HEPATITIS].

UNLABELLED: The aim of the work to study the influence of the low-intensive laser therapy on the endothelium function in chronic virus hepatitis patients. RESEARCH METHODS: All patients have been divided into three groups: In the first (control) group (30 persons) the traditiona medicamentous therapy was used only, the patients of the experimental 11 group (45 person) alongside with complex medicamentous therapy received the course of intravenous laser therapy and Ill group of patients (45 person) received a rate complex medicamental and laser (cutaneous) therapy. RESULTS: Medicamentous therapy of patients chronic virus hepatites is not accompanied by authentic improvement of the maintenance in plasma of blood NOx, and inclusion in a complex of medical actions of laser therapy promotes authentic improvement of parameters in plasma of blood NOx. THE CONCLUSION: Various methods of laser therapy improve NO--producing function endothelium, improve a functionacondition of vascular endothelium.

[The evaluation of exocrinous function of pancreas in patients with chronic pancreatitis].

The article deals with studying the impact of low-intensity laser therapy on the exocrinous function of pancreas in patients with chronic pancreatitis in exacerbation stage. The sample included 49 patients aged from 36 to 69 years. They were allocated on the main (39 patients) and control (10 patients) groups. The patients from the main group received pharmaceutical treatment along with low-intensity laser therapy. The patients from control group received only pharmaceutical treatment. The study demonstrated the positive impact of comprehensive therapy with low-intensity laser therapy added on the exocrinous function of pancreas in patients with chronic pancreatitis.

Effect of intravenous laser irradiation of the blood on plasma content of ceruloplasmin in patients with chronic pancreatitis.

Ceruloplasmin content in the blood plasma significantly increased in patients with chronic pancreatitis during exacerbation of the disease. Addition of intravenous laser irradiation of the blood to complex therapy of patients with chronic pancreatitis normalized ceruloplasmin content in the plasma.

[Types of microcirculation and laser therapy in chronic pancreatitis].

The aim of the study was to evaluate effect of low-intensity laser therapy (LILT) on systemic circulation in patients with chronic pancreatitis (CP) in the phase of exacerbation. 65 patients aged 36-77 years were divided into study (n = 20) and control (n = 45) groups. In addition, 30 healthy subjects were examined. Patients of the study group received drug therapy combined with intravenous blood or skin laser irradiation. Controls were treated with medicinal preparations alone. CP was diagnosed based on characteristic pain syndrome, compromised secretory function of the pancreas, results of laboratory and instrumental analysis. Microcirculation was studied by laser Doppler flowmetry with a LAKK-02 apparatus (Lazma, Russia). CP patients had heterogeneous microcirculation with a significantly increased frequency of its pathologic types (spastic, hyperemic, spastic-congestive). Major characteristics of microcirculation were significantly different from those in healthy subjects. Combination of drug therapy and LILT substantially improved microcirculation regardless of its hemodynamic type.

[Platelet aggregatory properties in patients with chronic pancreatitis and possibilities of correcting their impairments].

The purpose of the investigation was to study the impact of low-intensity laser therapy (LILT) on platelet aggregatory properties in patients with chronic pancreatitis (CP) on an exacerbation. A total of 105 patients aged 36 to 77 years who were divided into a study group (n = 60) and a control one (n = 45) were examined. Thirty persons who formed a healthy group were additionally examined. In the study group patients, drug therapy was supplemented by LILT via various methods. The control group received only drug therapy. The investigation revealed that patients with CP on an exacerbation showed diverse changes in platelet aggregatory properties towards hyperaggregation. LILT was ascertained to have a normalizing effect on platelet aggregatory properties in the study group patients.

[Parameters of lipid peroxidation and antioxidative protection in patients with chronic pancreatitis treated by low-intensity laser therapy].

The objective of this study was to evaluate the influence of low-intensity laser therapy (LILT) on the processes of lipid peroxidation (LPO) and antioxidative protection (AOP) in patients with chronic pancreatitis. A total of 78 patients aged from 36 to 77 years were treated with LILT in addition to conventional therapy; the patients of the control group (n = 40) received only medicamentous therapy. Examination of the patients in the exacerbation phase of chronic pancreatitis revealed activation of LPO processes and differently-directed shifts of AOP components. These changes are supposed to reflect variations in the activity of the inflammatory processes in the pancreas and oxidative stress on this organ.

[Effect of various low-intensity laser methods of treatment on an aggregation properties of erythrocytes in chronic pancreatitis].

The aim of the present investigation is to study the influence of low-intensity laser therapy at the aggregate function of erythrocytes in patients with chronic pancreatitis. 118 patients aged 36-77 years old were examined and divided into 2 groups: the experimental (73 patients) and the control group (45 patients). The experimental group has had a complex drug and laser therapy of various therapeutic techniques. Control group has had only drug therapy. In this study were found out various changes of aggregate properties of erythrocytes in patients with exacerbation of chronic pancreatitis. Was established normalizing effects of low-intensity laser therapy on erythrocytes aggregation in experimental group.

[Efficacy of different laser treatments in combined therapy of patients with gastroduodenal ulcer].

AIM: To investigate efficacy of different methods of low-intensity laser treatment (LILT) in therapy of exacerbated gastroduodenal ulcer. MATERIAL AND METHODS: A total of 111 gastroduodenal ulcer (GDU) patients were divided into two groups: the study group (81 patients) and control group (30 patients). Patients from the study group received combined treatment with anti-ulcer drugs and LILT performed by three methods: intravenous laser radiation of blood (ILRB), epicutaneous radiation (ER) and combination ILRB+ER. Control patients received medication alone. The efficacy of the treatment was assessed by the time of ulcer defect heeling, duration of hospital stay, clinical symptoms of the disease exacerbation manifesting with three syndromes: pain, dyspepsia, asthenovegetative syndrome. RESULTS: The shortest heeling of ulcer defect was achieved in the patients treated with ILRB+ER combination: 17.8 +/- 0.8 and 19.3 +/- 3.4 days for gastric and duodenal ulcer, respectively (p < 0.05 and p < 0.01 vs control). CONCLUSION: Combined treatment of gastric and duodenal ulcer with inclusion of laser radiation (ILRB, ER, ILRB+ER) is effective in therapy of ulcer.

[The influence of low-intensive laser therapy on the aggregation properties of thrombocytes in patients with peptic ulcer].

The purpose of the study was to evaluate the influence of low-intensive laser therapy (LILT) on the aggregation properties of thrombocytes in patients with exacerbation of peptic ulcer (PU). The subjects, 111 patients aged 18 to 63, were divided into two groups: the main group (n = 81), and the control group (n = 30). In addition there were 15 healthy people who also underwent examination. Patients in the main group received complex treatment with untiulcer drugs and different methods of laser therapy: intravenous laser irradiation of blood, cutaneous irradiation, and a combination of both. The control group was treated with drugs only. The study found various changes in the aggregation properties of thrombocytes in patients with PU exacerbation, which consisted mostly in hyperaggregation. LILT had a normalizing effect on the aggregation properties of thrombocytes in patients of the main group.

[State of humoral immunity and phagocytic activity of neutrophils in patients with ulcer and effect of low-intensity laser therapy]. / Sostoianie gumoral'nogo immuniteta i fagotsitarnoi aktivnosti neitrofilov u bol'nykh iazvennoi bolezn'iu i vliianie na nikh nizkointensivnoi lazernoi terapii.

The aim of our investigation was to study the influence of low-intensity laser therapy at the immunologic parameters and Helicobacter pylori (HP) microbial contamination in patients with exacerbation of peptic and duodenal ulcer. 100 patients aged 18-65 were examined and divided into 2 groups. The experimental group (75 patients) underwent a complex drug and laser therapy of various therapeutic techniques. The control group (25 patients) underwent only drug therapy. The results of this study show the immunocorrective effect of different methods of low-intensity laser therapy in the exacerbation period and more essential decrease of HP microbial contamination in the experimental group.