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6.
Vopr Med Khim ; 25(3): 242-5, 1979.
Article in Russian | MEDLINE | ID: mdl-452486

ABSTRACT

Effect of precipitating antibodies against pig pancreatic kallikrein on the BAEE-esterase activity was studied in human blood plasma and in rabbit blood serum, activated by kaolin. An inhibitory effect of the antibodies on the increased BAEE-esterase activity was observed within the first minute of incubation after treatment with kaolin. The inhibition of the BAEE-esterase activity constituted 65.1% in human blood plasma and 40.9% in rabbit serum. Possible mechanism is discussed on the inhibition of contact activation of arginine esterase in human and rabbit blood by antibodies against pancreatic kallikrein.


Subject(s)
Arginine/immunology , Esterases/blood , Kallikreins/immunology , Pancreas/immunology , Precipitins/immunology , Animals , Enzyme Activation/drug effects , Humans , Immunization , In Vitro Techniques , Kaolin/pharmacology , Rabbits , Swine , Time Factors
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