Subject(s)
Neovascularization, Pathologic/etiology , Optic Disk/blood supply , Optic Nerve Diseases/etiology , POEMS Syndrome/complications , Adult , Drug Therapy, Combination , Fatal Outcome , Female , Follow-Up Studies , Glucocorticoids/therapeutic use , Humans , Immunosuppressive Agents/therapeutic use , Neovascularization, Pathologic/diagnosis , Neovascularization, Pathologic/drug therapy , Optic Nerve Diseases/diagnosis , Optic Nerve Diseases/drug therapy , POEMS Syndrome/diagnosis , POEMS Syndrome/drug therapyABSTRACT
Tears of the retinal pigment epithelium have been described as a complication of pigment epithelial detachment in the elderly. The authors report tears occurring in diverse clinical settings: an asymptomatic chorioretinal scar; a rhegmatogenous retinal detachment; and a widespread, nonrhegmatogenous detachment.
Subject(s)
Choroid , Cicatrix , Retinal Detachment/diagnosis , Retinal Perforations/diagnosis , Aged , Female , Fluorescein Angiography , Humans , Male , Middle Aged , Retinal Hemorrhage/diagnosis , Wound HealingABSTRACT
Two young women noted acutely altered vision while suffering an adverse reaction to an intravenous injection of contrast agent for computerized tomography. One patient initially showed swollen maculas with subtle opacification of the parafoveal retina. Deep retinal lesions typical of acute macular neuroretinopathy were present later in both cases. Paracentral scotomas corresponding to the fundus lesions were present in both patients but subsequently improved. The temporal relationship of the onset of symptoms and the retinal abnormalities to the adverse reaction suggests that acute macular neuroretinopathy in these patients was caused either by the adverse reaction or its treatment.
