ABSTRACT
Endometrial carcinoma is the most common invasive neoplasm of the female genital tract and is associated to the elevated levels of unopposed estrogen, especially in postmenopause. Ovarian Steroid cell tumors are rare tumors and they are named according to the origin of cell. The most common cancer of the female genital tract is the endometrial adenocarcinoma and it accounts for 7% of all invasive cancers in women. In the present case report, the authors present a 59-year-old multiparous woman with a postmenopausal bleeding complaint and they discuss the case of ovarian steroid cell tumor associated with endometrioid adenocarcinoma of endometrium. Endometrial adenocarcinoma is the most common cancer of female genital tract and its contemporarity with an ovarian steroid cell tumor is extremely rare.
Subject(s)
Carcinoma, Endometrioid/pathology , Endometrial Neoplasms/pathology , Neoplasms, Multiple Primary/pathology , Ovarian Neoplasms/pathology , Sex Cord-Gonadal Stromal Tumors/pathology , Female , Humans , Middle AgedABSTRACT
AIMS: The aim of this study was to evaluate clinical accuracy of magnetic resonance imaging (MRI) staging of myometrial invasion in patients with endometrial carcinoma. METHODS: The study group consisted of 37 women with endometrial carcinoma who underwent preoperative workup, including MRI, and surgical staging at Goztepe Training Hospital, Istanbul, Turkey. We collected clinical, MRI, surgical and histopathological data of the study subjects from patients' charts. RESULTS: The mean patient age was 57 years (range 39-76 years). Of the subjects, 32 (86.5%) had endometrioid carcinoma. After histopathological evaluation, we found that four (10.8%) patients had no myometrial invasion, 14 (37.8%) had superficial myometrial invasion, and 19 (51.3%) had deep myometrial invasion. Overall, the accuracy of MRI staging increased in accordance with the increase of surgical stage of endometrial carcinoma. Overall, clinical success of MRI staging was higher in patients with deep myometrial invasion. CONCLUSION: The accuracy of MRI to depict the depth of myometrial invasion increases in accordance with surgical stage in patients with endometrial cancer. The combination of MRI and clinical findings may be helpful in determining the extent of surgery.
Subject(s)
Endometrial Neoplasms/pathology , Magnetic Resonance Imaging/methods , Myometrium/pathology , Adult , Aged , Female , Humans , Middle Aged , Neoplasm Invasiveness , Tomography, X-Ray ComputedABSTRACT
Ganglioneuroma is a rare benign neurogenic tumor originating from the sempathoadrenal nervous system and is considered the benign counterpart of neuroblastoma, lacking the immature neuroblastic cells. A case of pelvic ganglioneuroma is described.
Subject(s)
Ganglioneuroma/pathology , Ganglioneuroma/surgery , Pelvic Neoplasms/pathology , Pelvic Neoplasms/surgery , Female , Follow-Up Studies , Ganglioneuroma/diagnosis , Humans , Hysterectomy/methods , Immunohistochemistry , Magnetic Resonance Imaging , Middle Aged , Neoplasm Staging , Ovariectomy/methods , Pelvic Neoplasms/diagnosis , Retroperitoneal Space , Risk Assessment , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
Synchronous primary cancers of the endometrium and ovary are found in 5% of women with endometrial cancer and 10% of women with ovarian cancer. In the present case, a multigravid 46-year-old woman complained of lower abdominal pain and abdominal distension. She did not define abnormal uterine bleeding. Screening ultrasound revealed a papillary containing structure, irregular, cystic 16 x 15 x 10 cm right ovarian mass. Preoperative endometrial biopsy revealed endometrioid adenocarcinoma. Ascites sampling, radical hysterectomy, bilateral salpingo-oophorectomy, pelvic and paraaortic lymphadenectomy, omentectomy, appendectomy and cytologic sampling of the undersurface of the diaphragm were carried out. Intraoperative and histological examinations showed Stage IIIC papillary serous carcinoma and stage IC endometrioid adenocarcinoma. Synchronous genital tract neoplasms constitute a more common clinical problem than would generally be expected.
Subject(s)
Carcinoma, Endometrioid/diagnosis , Endometrial Neoplasms/diagnosis , Neoplasms, Multiple Primary/etiology , Ovarian Neoplasms/diagnosis , Carcinoma, Endometrioid/surgery , Endometrial Neoplasms/surgery , Female , Humans , Middle Aged , Neoplasms, Multiple Primary/pathology , Ovarian Neoplasms/surgeryABSTRACT
OBJECTIVES: We retrospectively analyzed six cases between 1986 and 2002 that had been operated within our unit with the diagnosis of migration of an intrauterine contraceptive device (IUD). Although an IUD is an effective contraceptive method, the migration of one is a rare but serious complication. The aim of this report is to emphasize the management and therapy of this complication. CASES: Out of six patients, three patients with occurring pregnancy, two with pelvic pain and one with a missing IUD incidentally diagnosed during a routine follow-up gynecological examination, were admitted to our clinic. The diagnosis of perforation and transuterine migration of the IUD was confirmed with a plain abdominal X-ray with a hysterometer placed in the uterus, hysterosalpingography and ultrasound. One patient was diagnosed as having a perforated rectosigmoid bowel intraoperatively and one presented with perforation of the bladder. In the remaining four cases, the IUD only migrated into the abdominal cavity without any organ perforations. One IUD was extracted laparoscopically, one was removed through the vagina by colpotomy and, in the other four cases, a laparotomy had to be performed. Patients were discharged without any complications. CONCLUSION: The most serious potential complication of IUD use is uterine perforation and this can cause severe morbidity. When an IUD is located in the abdominal cavity, it should be carefully managed and removed, even in an asymptomatic patient.
