Subject(s)
Angiotensin-Converting Enzyme Inhibitors/therapeutic use , Cardiac Output, Low/drug therapy , Cardiac Output, Low/etiology , Myocardial Infarction/complications , Angiotensin-Converting Enzyme Inhibitors/pharmacology , Animals , Cardiac Output, Low/physiopathology , Clinical Trials as Topic , Hemodynamics/drug effects , Humans , Myocardial Infarction/drug therapy , Myocardial Infarction/physiopathology , Myocardial Reperfusion Injury/drug therapy , Time FactorsABSTRACT
Seven two patients with coronary heart disease complicated with paroxysmal atrial fibrillation were studied by using accelerated atrial vector cardiography and M-mode echocardiography. Vector cardiography made it possible to reveal the signs of left atrial hyperfunction with normal left atrial echocardiographic dimensions. There were lower values for left ventricular myocardial contractility in parallel with higher echocardiographic dimensions of the left atrium. In the patients examined, progression of cardiosclerosis was accompanied by decreased amplitude values for the P loop on the vector cardiogram strip along with slower intraatrial conduction with an increase in the size of the left atrial cavity.
Subject(s)
Atrial Fibrillation/physiopathology , Heart Atria/physiopathology , Adult , Aged , Aged, 80 and over , Echocardiography , Electrocardiography , Humans , Middle Aged , Myocardial Contraction , VectorcardiographyABSTRACT
Seventy three patients with coronary heart disease (CHD) complicated by paroxysmal atrial fibrillation (PAF) were examined. Vectorcardiography developed by I. A. Akulinichev and M-mode echocardiography were used to assess the status of left atrial and ventricular myocardia. An interrelationship was examined between the electrophysiological and echocardiographic parameters of myocardial performance, depending on the stage of circulatory insufficiency (CI). The patients with PAF-complicated CHD, unlike those with CHD alone, showed more severe myocardial conduction abnormalities despite the stage of CI. There were signs of compensatory left ventricular overload in the absence of clinical signs of CI. Comparison of ultrasound examination findings with high performance atrial vectorcardiographic ones increases the possibility of accurately assessing the cardiac performance by using noninvasive tools of examinations.
Subject(s)
Coronary Disease/physiopathology , Echocardiography , Heart/physiopathology , Hemodynamics , Myocardial Contraction , Vectorcardiography , Adult , Aged , Aged, 80 and over , Atrial Fibrillation/physiopathology , Heart Atria , Humans , Middle AgedABSTRACT
It has been shown that the overwhelming majority of myasthenia patients manifest changes in the cardiovascular system characterized by cardiac pains of different nature, duration and intensity, by electrocardiographic changes and lowering of the central hemodynamics and myocardial contractility. A direct relationship was established between heart involvement into the pathological process and myasthenia gravity as well as the underlying disease standing. The changes in cardiovascular function were not affected by the acute use of neostigmine.
Subject(s)
Hemodynamics/drug effects , Myasthenia Gravis/diagnosis , Neostigmine , Adult , Chronic Disease , Combined Modality Therapy , Female , Hemodynamics/physiology , Humans , Male , Middle Aged , Myasthenia Gravis/physiopathology , Myasthenia Gravis/therapyABSTRACT
Atrial and left-ventricular myocardial activity was assessed in 85 coronary patients with paroxysmal atrial fibrillation. Their age varied between 43 and 88 years. The methods used included ECG, amplified atrial vectorcardiography after I. T. Akulinichev's schedule (amplification: 1 mv = 100 mm) and M-scan echocardiography. The comparison of these methods has substantiated criteria for the selection of differential treatment and preventive measures in these patients, on the basis of the prevailing type of atrial myocardial changes ("arrhythmic", "hemodynamic" or "combined" ones). A supportive treatment with cardiotonic agents is advisable in cases of the "hemodynamic" type with apparent signs of the overstrain (dilation) of the left atrium or both atria. In the "arrhythmic" variant, where conductivity, automatism and excitation disorders are predominant, antiarrhythmic agents (cordaron, quinidine, adrenoblockers) are indicated while the "combined" type calls for combined treatment with cardiotonic and antiarrhythmic agents.