ABSTRACT
We observed among 265 children with a chronic rhinopathy: 187 allergic rhinopathies, associating sneezing, rhinorrhea and nasal eosinophilia, particularly caused by a sensitization for mites. 10 non allergic eosinophilic rhinopathies with identical clinical signs, and major nasal eosinophilia without any allergic factor. 68 non allergic non eosinophilic rhinopathies, where are preponderant nasal obstruction, olfaction troubles, ORL infections (otitis and sinusitis). Their etiology is probably various: psychic factors, ciliary dyskinesias, vasomotor phenomena...
Subject(s)
Rhinitis/classification , Child , Chronic Disease , Eosinophilia/diagnosis , Eosinophilia/pathology , Female , Humans , Hypersensitivity, Immediate/diagnosis , Male , Nasal Mucosa/pathology , Rhinitis/diagnosis , Rhinitis/pathology , Rhinitis, Vasomotor/diagnosis , Rhinitis, Vasomotor/pathologyABSTRACT
Among 248 allergic children we noted 44 children (21%) with strongly or moderately positive cutaneous tests (In seven out of these tested children respiratory provocation tests are very positive). They are urban children and their houses are not different from other allergic children. They are mostly boys (72%), more than 5 years old (91%), with an asthma (84%), a radiological sinusitis (45%), an hypereosinophilia (88%) and elevated total IgE (90%). 43/44 children also have positive cutaneous tests to Dermatophagoides pteronyssinus mite. Since respiratory sensitivity is exquisite, we undertook a specific hyposensitization for some patients with encouraging results.
Subject(s)
Allergens/administration & dosage , Hypersensitivity, Immediate/etiology , Mites/immunology , Animals , Antibody Specificity , Bronchial Provocation Tests , Child , Child, Preschool , Female , Humans , Hypersensitivity, Immediate/diagnosis , Immunoglobulin E/analysis , Male , Nasal Provocation Tests , Skin TestsABSTRACT
Does immediate respiratory allergy with stemphylium exist? About 39 provocation tests. We present 39 children with positive cutaneous and/or RAST tests for stemphylium mold. Provocation tests individualize 19 patients (14 boys and 4 girls, 10 to 16 years old in 17/19) with a respiratory sensitivity: 6/10 by passive anterior rhinomanometry and 13/15 by bronchial tests. Clinical symptoms are asthma and spasmodic rhinitis (14/19), predominantly from june to august. We noted a mite allergy in 11 cases and a grass pollenosis in 13 children. Positive cutaneous and/or RAST tests are found for alternaria mold in 13/19 cases. We undertook a specific hyposensitization in 14 children with a three years experience in 10 cases. Tolerance is excellent. This provocation respiratory exploration shows the important role played by stemphylium mold in the etiology of recurring respiratory incidents in children.
Subject(s)
Allergens/administration & dosage , Hypersensitivity, Immediate/diagnosis , Mitosporic Fungi/immunology , Adolescent , Bronchial Provocation Tests , Child , Child, Preschool , Female , Humans , Male , Manometry , Nasal Provocation Tests , Respiratory Hypersensitivity/diagnosis , Skin TestsABSTRACT
Place for Passive Anterior Rhinomanometry (PAR) in mite allergic children. PAR is a simple method to investigate chronic or recurrent rhinopathies in children. Among 59 investigations with a Dermatophagoides pteronyssinus extract, we found 27 positive responses, 3 doubtful results and 32 negative explorations. Nasal sensitization is usually important: the liminal dose is less than 250 mcg in 17/28 cases. Most children have no bronchial sensitivity. None of 14 children with negative cutaneous and RAST tests have nasal sensitivity. When cutaneous and RAST tests are both positive, 12/16 positive PAR are found. We note a nasal sensitivity in 3/5 cases with only cutaneous test positive and 12/26 cases with only RAST tests positive. For other mites a nasal sensitivity is found in 8 out of 14 explorations (Tyrophagus and Glyciphagus especially). Among all patients when cutaneous tests, RAST tests and history are doubtful for the real part played by mites in the child rhinopathy, nasal exploration allows more explicit diagnostic and therapy.
Subject(s)
Manometry , Mites/immunology , Rhinitis, Allergic, Perennial/diagnosis , Adolescent , Allergens/administration & dosage , Animals , Bronchial Provocation Tests , Child , Child, Preschool , Female , Humans , Male , Radioallergosorbent Test , Rhinitis, Allergic, Perennial/etiology , Skin TestsABSTRACT
Is Mugwort pollenosis frequent among children in North of France? In North of France where no ragweed grows, mugwort (artemisia) is after grasses and plantago, the third pollenosis in children. Among 184 children with summer clinical signs, positive cutaneous tests with a mugwort extract are noted in 40 patients (21%). RAST are positive only in 23 on 34 children with positive cutaneous test. Among the 40 children only two are less 5 years old and 26 are more 10 years old. Respiratory provocation tests confirm in 13/19 cases a sensitization of upper or lower respiratory tract. No food allergy exists among those children.
