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1.
J Antibiot (Tokyo) ; 41(2): 157-69, 1988 Feb.
Article in English | MEDLINE | ID: mdl-3356604

ABSTRACT

Paulomycin A2 (C34H46N2O17S), paulomycin C (C32H42N2O17S), paulomycin D (C31H40N2O17S), paulomycin E (C29H36N2O16S) and paulomycin F (C29H38N2O16S) have been isolated from fermentations of Streptomyces paulus strain 273. The structure of these compounds was determined using NMR and mass spectroscopic techniques. The new paulomycins, like paulomycins A and B (J. Antibiotics 35: 285-294, 1982) are highly active mainly against Gram-positive organisms.


Subject(s)
Anti-Bacterial Agents/isolation & purification , Anti-Bacterial Agents/pharmacology , Chemical Phenomena , Chemistry , Chromatography, High Pressure Liquid , Cyclohexenes , Disaccharides/isolation & purification , Disaccharides/pharmacology , Gram-Positive Bacteria/drug effects , Magnetic Resonance Spectroscopy , Mass Spectrometry , Microbial Sensitivity Tests
2.
Antimicrob Agents Chemother ; 19(3): 493, 1981 Mar.
Article in English | MEDLINE | ID: mdl-7247371

ABSTRACT

Gamma-aminobutyric acid was isolated from ruptured cells of Streptomyces lincolnensis. Its isolation and purification by preparative liquid-solid chromatography and subsequent identification by gas chromatography-mass spectroscopy are reported.


Subject(s)
Streptomyces/analysis , gamma-Aminobutyric Acid/analysis , Mass Spectrometry
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