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Sci Rep ; 10(1): 17652, 2020 10 19.
Article in English | MEDLINE | ID: mdl-33077840

ABSTRACT

The present study was undertaken to determine the prevalence of endplate junction failure in a smaller cohort of Danish patients with lumbar disk herniation and compare this to the previously published data from India. Consecutive patients seen in a large regional hospital spine-care unit, with a clinical presentation suggesting a lumbar disk herniation with concomitant radiculopathy and confirmatory recent MRI were included. Additional imaging by CT was performed as part of the study and these were analyzed with specific attention to endplate junction failures. For ethical reasons, the number of participants was kept to a minimum and a total of 26 patients were included. The prevalence (n = 5) of endplate junction failure was found to be statistically significantly lower than that previously reported. Our findings do not echo those previously reported in an Indian population: Endplate junction failure was indeed observed, but at a significantly lower rate. We discuss potential reasons for the difference in findings with due attention to the weaknesses of the current study.


Subject(s)
Intervertebral Disc Displacement/pathology , Lumbar Vertebrae , Annulus Fibrosus/pathology , Denmark , Female , Humans , Intervertebral Disc Displacement/drug therapy , Intervertebral Disc Displacement/etiology , Lumbar Vertebrae/diagnostic imaging , Lumbar Vertebrae/pathology , Magnetic Resonance Imaging , Male , Middle Aged , Prevalence , Radiculopathy/etiology , Radiculopathy/pathology , Tomography, X-Ray Computed
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