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1.
J Pharm Bioallied Sci ; 16(Suppl 2): S1365-S1368, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38882893

ABSTRACT

Objective: Evaluating the canal-centering and apical transportation ability of endodontic file systems working with different kinematics but of similar cross section. Materials and Methods: Sixty human maxillary first molar mesiobuccal (MB) roots were assigned to three experimental groups based on instrumentation techniques: Reciproc Blue (RB), Mtwo (M2), and OneShape (OS). Pre- and post-instrumentation micro-computed tomographic analysis was performed. Centering ability and apical transportation were analyzed at 3 mm, 6 mm, and 9 mm short of the apex. Statistical analysis was conducted using Mann-Whitney U test and Kruskal-Wallis test. Results: OS showed better canal-centering ability than RB and M2 at 3 mm, 6 mm, and 9 mm. No significant difference among the tested groups was observed during the assessment of apical transportation (P < 0.05). Conclusion: The systems evaluated safely prepared curved MB canals with minimal canal transportation. OS showed superior canal-centering ability compared to the other two groups.

2.
Cureus ; 16(5): e60354, 2024 May.
Article in English | MEDLINE | ID: mdl-38883127

ABSTRACT

Calotropis procera (C. procera) is a versatile plant often used for fuel, fodder, wood, fiber, phytoremediation, medicine, and synthesis of nanoparticles. Its ability to tolerate abiotic stresses and its morphophysiological adaptation have made it popular worldwide. Currently, it is identified as an environmental weed across the world. C. procera owes its therapeutic qualities to the secondary metabolites like tannins, alkaloids, and phenols present in it. New synthetic drugs are being formulated by using these secondary metabolites as a prototype. This review aimed to provide a summary of the chemometric profile, toxicity, and pharmacological activities of the aqueous leaf extract of C. procera based on the current literature.

3.
J Conserv Dent Endod ; 26(6): 688-692, 2023.
Article in English | MEDLINE | ID: mdl-38292749

ABSTRACT

Background: The application of cavity cleansers for cavity disinfection can be a crucial step in the longevity of restorations. The objective of the present study was to compare the effect of the application of a new quaternary ammonium silane (QAS)-based cavity cleanser (2% K21 QAS), with other commercially available cavity disinfectants on the bond strength of resin-modified glass ionomer cement (RMGIC). Materials and Methods: The buccal surfaces of 40 extracted premolars were trimmed to obtain a flat dentinal surface and were randomly divided into four experimental groups depending on the cavity cleansers used before restoration. Group 1: 2% chlorhexidine (CHX), Group 2: QAS (FiteBac 2% K21 QAS), Group 3: silver diamine fluoride-potassium iodide (Riva Star, SDF-KI), and Group 4: 3% hydrogen peroxide (H2O2). Then, a predetermined dimension of RMGIC restoration was bonded to the treated dentin surfaces. Following this, each sample was tested for shear bond strength (SBS) using a universal testing machine at a crosshead speed of 0.5 mm/min. Results: Among the experimental groups, SDF-KI has shown the highest mean SBS, followed by 2% K21 QAS, and 2% CHX, which have shown almost comparable results. The 3% H2O2 group has shown the lowest values. Conclusion: According to the results of the present study, 2% K21 QAS has the potential to be used as an effective cavity cleanser before the placement of RMGIC restorations. Since its application does not affect the bond strength of restoration, it can be successfully used as an alternative to CHX and SDF-KI.

4.
J Conserv Dent ; 21(5): 542-545, 2018.
Article in English | MEDLINE | ID: mdl-30294118

ABSTRACT

BACKGROUND: Longevity of composite restoration in the oral cavity is dependent on various factors. One such factor is exposure to various foods and beverages which could alter the properties of the material. AIM: The aim of this in vitro study was to evaluate the effect of most widely consumed alcoholic beverages on shear bond strength of composites to enamel. MATERIAL AND METHODS: A total of seventy human premolars were embedded in acrylic resin blocks. Labial enamel surfaces was flattened, etched, bonded, and restored with composite resin (Tetric N Ceram - Ivoclar Vivadent AG, Schaan, Liechtenstein). The specimens were randomly divided into four groups: Group I: beer; Group II: wine; Group III: whiskey, and Group IV: artificial saliva. Group I to Group III were again divided into moderate (Group IA, IIA, and IIIA) and heavy (Group IB, IIB, and IIIB) consumption subgroups. The specimens were soaked in their respective groups for 90 min daily in Group IA, IIA, and IIIA and for 30 min every alternate day in Group IB, IIB, and IIIB until 30 days. Universal testing machine was used to determine the shear bond strength of composite with enamel. STATISTICAL ANALYSIS USED: The values obtained were statistically analyzed using two-way analysis of variance followed by post hoc test with the significant level set at P < 0.05, using GraphPad prism software version 6.01. RESULTS: Group IIB showed the highest reduction in shear bond strength, with a mean value of 6.6 ± 1.2 Mpa in comparison to control with a mean value of 21.8 ± 1.6 Mpa. CONCLUSION: As the content of alcohol and time of exposure increased along with a decrease in the pH of alcoholic beverages, shear bond strength between composite and enamel decreased.

5.
J Conserv Dent ; 21(2): 226-229, 2018.
Article in English | MEDLINE | ID: mdl-29674830

ABSTRACT

AIM: The objectives of this study were to determine the bacterial contamination of the mobile phones that were used by the endodontist in comparison with the general dentist and also to determine the usefulness of titanium dioxide nanospray (TiO2 NS) in mobile phone decontamination. MATERIALS AND METHODS: Samples from the 60 mobile phones were taken using moist sterile swabs before, 10 min, and 1 week after the use of TiO2 NS. Before collection of the swabs, the participants' informed consent was obtained. Samples obtained were cultured on blood agar to identify bacterial isolates. RESULTS: All 60 mobile phone cultures were found to be culture positive. There was a significant reduction in the mean number of colony-forming units after decontamination with TiO2 NS (P < 0.001). CONCLUSIONS: The results from this study showed that the mobile phones may act as an important source of nosocomial pathogens and TiO2 NS would be an effective decontaminant. Therefore, it is important for dental professionals to practice routine mobile phone disinfection protocol to reduce the chances of occurrence of nosocomial infections.

6.
J Clin Diagn Res ; 11(7): ZC18-ZC21, 2017 Jul.
Article in English | MEDLINE | ID: mdl-28893035

ABSTRACT

INTRODUCTION: Chlorhexidine (CHX) is generally used as the final irrigating solution in root canal therapy. Recent studies have reported that, toxic precipitates containing parachloroaniline (PCA) are formed when CHX reacts with sodium hypochlorite (NaOCl). Whereas, Alexidine (ALX), a bisbiguanide disinfectant similar to CHX, has proven to form no precipitates with NaOCl. AIM: To compare antimicrobial activity of different concentrations of ALX with CHX individually and when combined with NaOCl against E. faecalis strains. MATERIALS AND METHODS: Different concentrations of ALX and CHX (0.5%, 1%, and 2%) were tested individually and when mixed with 2.5% NaOCl (1:1 ratio) using disc diffusion method against E. faecalis. After 24 hours incubation at 37°C, zones of inhibition were measured for each solution. The results obtained were statistically analysed using one way ANOVA and Scheffe's post-hoc tests. The p-value <0.001 was considered as highly significant. RESULTS: Regardless of the concentrations, ALX obtained the best results in comparison to CHX. There was no statistically significant difference between ALX + NaOCl and CHX + NaOCl mixtures. CONCLUSION: The present study showed that, the antimicrobial property of ALX against E. faecalis was found to be superior to CHX at same concentrations.

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