Salivary gland tumor incidence in adult patients in a tertiary hospital in Mexico from 2008 to 2019.

OBJECTIVE: To determine the incidence of salivary gland tumors in a population of a tertiary hospital in the State of Mexico, and to describe demographic variables. METHOD: An observational, cross-sectional and retrospective study of salivary gland tumors reported in a tertiary hospital in the State of Mexico in the period 2008-2019 is presented. RESULTS: A prevalence of 0.049% was found. There was no difference between sex in the studied population. Benign salivary gland tumors were the most frequent (86.7%). The age range most affected was 51-60 years. The most frequently found tumor was the pleomorphic adenoma, followed by Warthin's tumor. There was 13.33% of sialolipomas, and one myoepithelioma. There were no cases of sublingual gland tumors or minor salivary glands. CONCLUSION: Tumors of the major salivary glands are infrequent tumors; population cases from a central Mexican state and their demographic characteristics are presented to contribute to the information found in local and international literature.

OBJETIVO: Determinar la incidencia de los tumores de glándulas salivales en una población de un hospital de tercer nivel en el Estado de México y describir variables demográficas. MATERIAL Y MÉTODOS: Se presenta un estudio observacional, transversal y retrospectivo de los tumores de glándulas salivales reportados en un hospital de tercer nivel en el Estado de México en el periodo 2008-2019. RESULTADOS: Se encontró una prevalencia del 0.049%. No hubo diferencia entre sexos en la población afectada. Los tumores de glándulas salivales benignos fueron los más frecuentes (86.7%). El rango de edad mayormente afectado fue el de 51-60 años. El tumor más frecuentemente encontrado fue el adenoma pleomorfo, seguido por tumor de Warthin. Se presentó un 13.33% de sialolipomas y un mioepitelioma. No se presentó ningún caso de tumores de glándulas sublinguales ni glándulas salivales menores. CONCLUSIÓN: Los tumores de glándulas salivales mayores son tumores infrecuentes, se exponen casos de población de un Estado del centro de México y sus características demográficas para contribuir a la información encontrada en literatura local e internacional.

Analysis of CCR3 expression in corneal neovascularization in a murine model and human corneas.

The aim of this study was to examine the expression of the cytokines and chemokines receptor-3 (CCR3) molecule in endothelial cells and vascular structures in a murine model of corneal neovascularization and in samples of neovascularized human corneas. An immunofluorescence assay using the murine model showed a greater proportion and intensity of CCR3 in the epithelium and corneal subepithelial regions in corneas with neovascularization. In the absence of vascularization, no CCR3 was found. Of the 32 studied tissues, eight were vascularized and 24 were avascular. In the human corneas, vascularized corneas showed positive labeling for CD31 in all the analzedtissues, as well as positive labeling for CCR3. Therefore, all vascularized tissues showed positive coexpression of CCR3 and CD31, whereas none of the avascular corneas showed immunolabeling for either of these receptors. These results suggest that CCR3 could be a possible marker for corneal neovascularization with potential to be a therapeutic target.

Ocular dermoids: 116 consecutive cases.

PURPOSE: The aim was to describe the demographic and clinical data of 116 consecutive cases of ocular dermoids. METHODS: This was a retrospective case series and a review of clinical records of all the patients diagnosed with ocular dermoids. Both demographic and clinical data were recorded. Statistical analysis was performed with SPSS v. 18. Descriptive statistics are reported. RESULTS: The study included 116 consecutive patients with diagnosis consistent with ocular dermoids: corneal 18% (21), dermolipomas 38% (44), and orbital 44% (51). Sixty-five percent (71) were female, and 46% (54) were detected at birth. Secondary manifestations: amblyopia was present in 14% (3), and strabismus was detected in 6.8% (8). The Goldenhar syndrome was the most frequent syndromic entity in 7.5% (12) of the patients. Surgical resection was required on 49% (25) of orbital dermoids, 24% (5) of corneal dermoids, and 13% (6) of dermolipomas. CONCLUSIONS: Orbital dermoids were the most frequent variety, followed by conjunctival and corneal. In contrast to other reports, corneal dermoids were significantly more prevalent in women. Goldenhar syndrome was the most frequent syndromatic entity.

Bilateral keratectasia after photorefractive keratectomy.

PURPOSE: To report the clinical features, management, and outcome of a patient who developed bilateral ectasia after photorefractive keratectomy (PRK). METHODS: Case report of a 35-year-old man who underwent bilateral PRK. Preoperative uncorrected visual acuity was 20/200 in the right eye and 20/100 in the left eye. The patient's history was unremarkable and he denied a family history of ocular disorders. RESULTS: Two weeks after surgery, the patient presented with loss of visual acuity in both eyes. Uncorrected visual acuity was 20/80 in the right eye and 20/200 in the left eye. Objective refraction could not be obtained. Slit-lamp microscopy showed corneal thinning in both eyes. After examining the patient's family, his sister was found to have clinical and topographic keratoconus. CONCLUSIONS: Ectasia is a rare complication of PRK. We report the occurrence of bilateral ectasia after PRK in a patient with asymmetric bowtie topographies. We recommend that refractive surgery, even surface techniques such as PRK, be avoided in patients with a family history of keratoconus.