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Rev Sci Instrum ; 82(7): 076104, 2011 Jul.
Article in English | MEDLINE | ID: mdl-21806238

ABSTRACT

We have developed a laser Doppler velocimeter (LDV) for measuring velocity distributions in blood vessels. We converted a transmission-based LDV into a reflection-based LDV to make it suitable for clinical applications. The velocity distribution image of a serpentine flow channel obtained could be qualitatively explained by the numerical results. Finally, we evaluated the system by using it to measure injection of blood into a glass tube by a syringe pump. The results obtained demonstrate that erythrocytes can be used as seeding particles for the reflection-type micro multipoint LDV. The results obtained are useful as basic data for clinical applications.


Subject(s)
Blood Vessels/physiology , Laser-Doppler Flowmetry/instrumentation , Animals , Hemorheology , Male , Mice , Microcirculation , Molecular Imaging
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