Dengue virus infection in a traveller returning from Croatia to Germany.

Dengue virus (DENV) is endemic in south-east Asia and Central to South America. In August 2010, a DENV infection was diagnosed in a German traveller returning from a trip to Croatia in south-east Europe. The patient presented with fever and other typical symptoms of DENV-infection. Virological investigation revealed the presence of DENV-specific IgM, a rise in DENV-specific IgG and the presence of DENV NS1 antigen in the patient's blood.

[The first case of anisakiasis acquired in Austria]. / Anisakiasis - der erste in Osterreich akquirierte Fall einer seltenen Helminthozoonose.

Anisakiasis is caused by a fish parasite of the Nematode family. This kind of rare helminthozoonosis can mainly be found in countries where consumption of raw fish is traditionally high like Japan, the Netherlands, Pacific Islands, South Europe, Scandinavia, USA, and Canada. Man is the wrong hoste. Clinical manifestation depends on the localisation of penetration in the GI tract. In Japan, predominantly the stomach is affected in 97 % of cases, probably due to hypo- and achlorhydria; whereas mainly intestinal anisakiasis occurs in Europa. We report on a 67-year-old male patient with a gastric infestation of anisakiasis. The patient was on proton pump inhibitor which migh have caused the localisation of the infestation. The anisakis was an accidental endoscopic finding in a patient for control of an H. p.-positive gastric ulcer. Otherwise the patient was free of pain. The helminth (larva III) was endoscopically extracted. Thereafter, the patient remained in good health. Anisakis serology as well as repeated differential blood counts were without finding. The uneventful medical history and the normal blood findings indicate that our patient had a very early stage of infestation of anisakiasis. The patient reported no stay outside of Austria within the last years. However, he consumed on a regular basis "rolled pickled herring" produced by a well-known Viennese company for canned fish. This is the first documented case of this rare helminthozoonosis acquired in Austria.

Quality and reliability of current malaria diagnostic methods.

Malaria is a life threatening disease with a major impact on global health. The WHO declared an early diagnosis as one of the most important steps to fight the disease. The quality and the reliability of test results depend on the diagnostic tools used. Not every test meets the needs in every situation. PCR tests have the best sensitivity and specifity but are not as rapid as other tests and also due to the costs not available everywhere. The 'gold standard' method is to check stained blood slides, thick films require experienced persons to obtain correct results. So-called rapid tests are only additional tools no matter whether they are based on the detection of antigens, enzymes or plasmodial DNA by fluorescent staining. Some other blood bound markers may also provide a hint but are no sufficient tool for malaria diagnosis.

[Flying fitness of patients with infections]. / Flugtauglichkeit bei Infektionskrankheiten.

To certify fitness for (international) air flights one must differentiate between target groups, i.e. pilots, cabin crew and passengers and the stage of infection, i.e. acute and chronic phase of disease and (organ) deficiency after infection, respectively. Publications mostly show indefinite terms which makes principles of quality assessment and international harmonization difficult, in some instances even impossible. Whereas certification of fitness in pilots in respect of infectious diseases should ensure a safe travel problems of infectious diseases in cabin crew and passengers are mainly focused on the risk of avoidable sequelae concerning the person itself and of the transmission to other passengers, respectively.

Vibrio cholerae non-O1 septicaemia in a patient with liver cirrhosis and Billroth-II-gastrectomy.

This report deals with the first diagnosed case of Vibrio cholerae non-O1 septicaemia in Austria. After a vacation in Tunisia, a 51-year-old male patient with liver cirrhosis and Billroth-II-gastrectomy was admitted to hospital because of abdominal pain, growing ascites, and jaundice. Four days later, the patient developed a single peak of high fever (39.6 degrees C). A blood culture was drawn and treatment with amoxycillin/clavulanic acid commenced. The blood culture yielded Gram-negative comma-like rods which were identified as V. cholerae non-O1.

Antibiotic susceptibility of pneumococci isolated in Austria over a four-year period.

The antibiotic susceptibility of pneumococci isolated from clinical specimens from 1991 through 1994 was investigated. Of 305 strains tested by the agar dilution method, 16 (5.2%) were resistant to penicillin (MICs > or = 0.12 mg/l). Of the resistant strains, 0.3% showed high-level resistance (MIC > or = 2 mg/l). The rate of resistance to erythromycin (MIC > or = 4 mg/l) was 2.3%, to tetracycline (MIC > or = 8 mg/l) 8.5%, to chloramphenicol (MIC > or = 8 mg/l) 1.0%, and to trimethoprim sulfamethoxazole (MIC > or = 3.2/64 mg/l) 3.3%. Penicillin-resistant strains showed significantly higher resistance to the other antibiotics tested. Resistance to penicillin was higher in isolates from the respiratory tract than in those from blood and cerebrospinal fluid (6.2% vs. 2.4%, respectively). There was no increase in penicillin resistance from 1991 through 1994 (5.3% vs. 4.9%, respectively).

Yersinia enterocolitica septicemia in autologous blood transfusion.

BACKGROUND: Increasingly, autologous blood transfusions are used in elective surgical procedures to avoid the risk of infection due to allogeneic blood transfusion. CASE REPORT: A 64-year-old patient had to undergo the implantation of a total right hip endoprosthesis. During the transfusion of 1 unit of autologous packed red cells, the patient experienced high temperature and shock, which necessitated his observation in the intensive care unit for several days. Yersinia enterocolitica (type O:9) was isolated from the packed red cells, from the unit of fresh-frozen plasma separated from the same donation, and from one blood culture drawn from the patient. With appropriate therapy, the patient recovered without sequelae. CONCLUSION: Although autologous blood transfusions are safe with respect to transmission of human immunodeficiency virus or hepatitis B and C infections, the risk of bacterial septicemia remains.

The germ-spectrum problem and antibiotic-resistance in Bida and Minna hospitals--Nigeria.

In the present paper the occurrence of different species of Pseudomonas, of Acinetobacter calcoaceticum var. anitratum and Aeromonas hydrophila in hospitals is described. The possible human pathogenic significance is discussed.