ABSTRACT
BACKGROUND: The transitional cell carcinoma within the bladder diverticular is a rare and poorly known entity. AIM: To evaluate diagnostic and therapeutic approaches of transitional cell carcinoma within the bladder diverticular. METHODS: Thirty men and two women (median: 70 years; 44- 83 years) were included. The main reason for consultation was hematuria. The intra-diverticular tumor was suspected by radiological assessment in 9 patients only. All these patients underwent an endoscopic resection of the tumor. RESULTS: The histological study concluded to a pta stage in 16 patients, pt1 stage in 8 patients and invasive tumors in 8 patients. A complementary endovesical BCG-therapy was performed in patients with superficial tumors and a radical cystectomy in patients with invasive tumors. With an average follow-up of 27 months, seven recurrences were found in the group of superficial tumors, including 3 cases of progression to invasive stage. CONCLUSION: Bladder intra-diverticular tumors are rare and more common in elderly. In a bladder diverticulum, there are superficial tumors (pta, pt1) which are the most frequent and invasive tumors. Radical cystectomy is the gold standard for invasive tumors.Endoscopic resection combined with endo-vesical immunotherapy should be reserved for superficial tumors.
Subject(s)
Carcinoma, Transitional Cell/diagnosis , Carcinoma, Transitional Cell/therapy , Urinary Bladder Neoplasms/diagnosis , Urinary Bladder Neoplasms/therapy , Adult , Aged , Aged, 80 and over , BCG Vaccine/therapeutic use , Carcinoma, Transitional Cell/mortality , Cystectomy , Female , Humans , Male , Middle Aged , Urinary Bladder Neoplasms/mortalityABSTRACT
RéSUMé: Le carcinome épidermoïde de l'urètre masculin est une tumeur rare, les tumeurs de l'urètre tous types confondus représentant moins de 1 % des tumeurs de l'appareil urinaire. Le pronostic reste défavorable malgré un traitement chirurgical énergique. La radiochimiothérapie semble être un traitement prometteur, mais son rôle doit être défini par d'autres études.Nous rapportons un cas rare de carcinome épidermoïde de l'urètre bulbo-membraneux découvert à un stade localement avancé après observation d'une rupture urétrale transtumorale chez un homme âgé de 70 ans. Le patient a été traité, après drainage vésical, par une irradiation externe associée à une chimiothérapie par cisplatine, et est décédé après progression de la maladie sur un an.La rupture spontanée de l'urètre transtumorale est un mode de découverte exceptionnel témoignant d'une évolution locale défavorable, ce qui rend ces tumeurs difficilement opérables. Cependant, l'espoir actuel réside dans des protocoles thérapeutiques associant radiothérapie et chimiothérapie.
Subject(s)
Adenomatoid Tumor/pathology , Epididymis , Genital Neoplasms, Male/pathology , Scrotum , Adenomatoid Tumor/complications , Adenomatoid Tumor/diagnosis , Adenomatoid Tumor/surgery , Adult , Aged , Diagnosis, Differential , Epididymis/pathology , Epididymis/surgery , Genital Neoplasms, Male/complications , Genital Neoplasms, Male/diagnosis , Genital Neoplasms, Male/surgery , Humans , Male , Orchiectomy , Scrotum/pathology , Scrotum/surgery , Testicular Hydrocele/complications , Treatment OutcomeABSTRACT
Transrectal ultrasound is an important tool in detection and management of prostate cancer. Its role is to identify and characterize focal lesions before capsular invasion and metastases and to guide biopsy of the prostate. In this paper, we present a overview of the state of trans-rectal ultrasound imaging in prostate cancer.
