ABSTRACT
OBJECTIVE: This study was aimed to compare the effect of an Oak Gall extractbased cream and a metronidazole Gel on the bacterial vaginosis among women in reproductive age. MATERIAL AND METHODS: This was a double-blind, randomized controlled trial performed on 84 women with BV in reproductive age. Accordingly, the women were randomly assigned to the Oak Gall (nâ¯=â¯42) or metronidazole (nâ¯=â¯42) groups. Diagnosis of BV was confirmed when at least 3 of the 4 Amsel criteria were met by the participants (whitish-grey or thin homogeneous discharge, pHâ¯≥â¯4.5, the release of a fishy odor on the addition of 10 % KOH, and detection of clue cells > 20 % in the microscopic examination). For each group, either a methanol extract of Oak Gall vaginal cream or a metronidazole vaginal gel (5â¯g) was used as intravaginal for 5 consecutive days, and all the signs or symptoms were assessed by passing 4-7 days from the treatment completion. RESULTS: At baseline, the two groups were homogenous in terms of the vaginal burning, odor, dysuria, dyspareunia, and itching. Also, all women in both groups were free of symptoms (vaginal itching and burning sensation, bad odor, dysuria, and dyspareunia) by passing one week from the intervention (pâ¯<â¯0.001). The percent of bacterial vaginosis treatment was in 33(82.1 %) patients in terms of Oak Gall group and in 34(87.5 %) patients of Metronidazole group (p=0.56). Notably, Oak Gall was as effective and safe as metronidazole in the treatment of BV in reproductive-aged women. CONCLUSION: Oak Gall could be recommended for women in reproductive age who are uncomfortable with the potential side effects of synthetic drugs.
Subject(s)
Metronidazole/therapeutic use , Quercus , Vaginosis, Bacterial/drug therapy , Adult , Anti-Bacterial Agents/therapeutic use , Double-Blind Method , Female , Humans , Vaginal Creams, Foams, and JelliesABSTRACT
PURPOSE: The aim was to determine the effect of multisensory stimulation (MSS) on the depression and anxiety status among nursing home-dwelling elderly people in Ahvaz, Iran. DESIGN AND METHODS: This clinical trial study conducted on 28 old people living in nursing homes in Ahvaz, who were divided into two groups of intervention and control. The interventions included sensory stimulations of touch, sound, and sight for 4 weeks and 3 sessions weekly and 25 min per each session. FINDINGS: The mean depression and anxiety scores of the intervention group before and after the intervention were 14.5 ± 5.5 and 10.1 ± 5.3 and, 9.6 ± 8.1 and 6.1 ± 6.2, respectively. PRACTICE IMPLICATIONS: MSS could improve the condition of depression and anxiety in the elderly nursing home residents.