ABSTRACT
Peripheral nerve sheath tumor was found in a 7-year-old male mongrel dog. The tumors were located in the right cheek subcutis and oral submucosa. Histologically, neoplastic cells were arranged in streaming bundles, occasionally interlacing bundles or whorls of elongated and spindle cells. Cellular atypia was poor and mitotic figures were rarely observed. Ultrastructurally, neoplastic cells had basement membrane, typical of Schwann cells. One bundle of normal peripheral nerve fibers and some myelinated axons were seen within the tumor tissues. Immunohistochemically, neoplastic cells reacted to vimentin, glial fibrillary acidic protein, S-100 protein and neuron specific enolase. In addition to the above immunoreactions, the included nerve fibers were positive for myelin basic protein and neurofilament protein. This paper also discusses immunohistochemical findings on differential diagnosis in comparison with those of canine hemangiopericytomas reported hitherto.
Subject(s)
Dog Diseases/pathology , Mouth Neoplasms/veterinary , Neoplasm Recurrence, Local/veterinary , Nerve Sheath Neoplasms/veterinary , Animals , Biopsy/veterinary , Cheek/pathology , Dog Diseases/surgery , Dogs , Fatal Outcome , Immunohistochemistry , Male , Microscopy, Electron/veterinary , Mouth Mucosa/pathology , Mouth Neoplasms/pathology , Mouth Neoplasms/surgery , Nerve Sheath Neoplasms/pathology , Nerve Sheath Neoplasms/surgery , Schwann Cells/ultrastructureABSTRACT
For end-stage patients with malignant disease, home parenteral nutrition (HPN) is an effective and useful treatment in terms of pain control and nutritional support. Therefore, these patients are able to spend their final days at home with their family. In 1990, we started the treatment and have been experienced 109 cases. In this report, we evaluate these cases and which condition or circumstance are necessary to perform HPN for the terminal patients.
