ABSTRACT
BACKGROUND: Trachoma is the leading infectious cause of irreversible blindness. In areas where trachoma is endemic, active trachoma is common among preschool-aged children, with varying magnitude. There is a dearth of information on the prevalence of active trachoma among preschool-aged children (the most affected segment of the population). PURPOSE: The study aimed to assess the prevalence of clinically active trachoma and its associated risk factors among preschool-aged children in Arba Minch Health and Demographic surveillance site, Southern Ethiopia. PATIENTS AND METHODS: A community-based cross-sectional study was conducted among 831 preschool-aged children from May 01 to June 16, 2019. A pre-tested and structured interviewer-administered Open Data Kit survey tool was used to collect data. The study participants were selected using a simple random sampling technique by allocating a proportion to each kebeles. Both bivariable and multivariable logistic regression analyses were performed to identify associated factors. The level of statistical significance was set at a p-value of less than 0.05 in multivariable logistic regression. RESULTS: The overall prevalence of clinically active trachoma among preschool-aged children was 17.8% with 95% CI (15%, 20%). Time taken to obtain water for greater than thirty minutes (AOR=2.8,95% CI: 1.62, 5.09), presence of animal pens in the living compound (AOR=5.1, 95% CI: 3.15, 8.33), improper solid waste disposal (AOR=7.8,95% CI: 4.68,13.26), improper latrine utilization (AOR=2.5, 95% CI: 1.63,3.94), a child with unclean face (AOR=3.5, 95% CI: 2.12,5.97) had higher odds of active trachoma. CONCLUSION: The prevalence of clinically active trachoma among pre-school aged children was high. "Facial cleanliness" and "Environmental improvement" components of the SAFE strategy are vital components in working towards the 2020 target of eliminating trachoma. Therefore, stakeholders at different hierarchies need to exert continuing efforts to integrate the trachoma prevention and control programs with other public health programs, with water sanitation and hygiene programs and with the education system.
ABSTRACT
BACKGROUND: The human immunodeficiency virus (HIV) continues to be a major global public health problem with more than 35 million people worldwide infected so far. Evidence shows that HIV has been compromising the quality of life of people living with HIV (PLWH) even in this era of highly active anti-retroviral therapy (HAART). There has been little research into the quality of life of PLWH receiving HAART in Ethiopia. PURPOSE: The aim of this study was to assess the quality of life among PLWH attending anti-retroviral therapy at public health facilities of Arba Minch town, Southern Ethiopia, in 2019. PATIENTS AND METHODS: We conducted a cross-sectional study design on 391 randomly selected PLWH who were attending HAART. We used a systematic random sampling technique to select participants in public health facilities of Arba Minch town from February 16 to April 26, 2019. The interviewers administered a structured questionnaire consisting of the WHOQOL-HIV BREF tool to measure the quality of life. Socio-demographic variables of study participants were collected, together with variables related to their clinical status extracted from their clinical records. Percentage mean scores were calculated and the mean of percentage mean scores was taken as the cutoff to categorize participants into two groups representing poor and good quality of life. Simple binary logistic regression and multivariable logistic regression analyses were used to determine significant variables. All variables with p-value ≤ 0.25 in simple binary logistic regression were considered as eligible variables for multivariable logistic regression. Variables with p-value ≤ 0.05 in multivariable logistic regression were considered as predictor variables. RESULTS: Out of the 391 enrolled adult PLWH, 184 of them (47.1%) had poor of overall quality of life status, as estimated by the WHOQOL-HIV BREF tool. Good quality of life was positively associated with recent CD4 count greater than or equal to 500 cell/mm3 (AOR=1.96, 95% CI; 1.18-3.27), absence of depression (AOR=10.59, 95% CI; 6.16-18.21), normal body mass index (AOR=2.66, 95% CI; 1.18-3.27), social support (AOR= 6.18, 95% CI; 3.56-10.75) and no perceived stigma (AOR=2.75, 95% CI; 1.62-4.67). CONCLUSION: Nearly half of the adult PLWH receiving HAART at Arba Minch town had poor quality of life. High CD4 count, lack of social support, depression, and perceived stigma were associated with poor quality of life of PLWH. PLWH should be encouraged to be part of structured social support systems, such as associations of people living with HIV and mother support groups, in order to improve their social and psychological health. The health system should give attention to counseling on chronic care adherence and nutritional support to improve the quality of life of PLWH receiving HAART.
