Enhancing Interoceptive Abilities and Emotional Processing: Effects of HD-tDCS.

BACKGROUND: Interoception, the processing and integration of bodily signals, is crucial for emotional experiences and overall well-being. The interoceptive network, including the somatosensory cortices, has been recognized for its role in interoceptive and emotional processing. High-definition transcranial, direct-current stimulation (HD-tDCS) has been demonstrated to modulate brain activity in the primary somatosensory cortex (S1). Based on those findings, we hypothesized that anodal HD-tDCS over the right S1 would enhance interoceptive abilities and heighten emotional perception. METHODS: Thirty-six healthy adults participated in two sessions separated by at least one week. A 20-min HD-tDCS stimulation (2 mA), and a sham stimulation, were applied in randomized order. Both conditions involved pre-tDCS physical activation by ergometer cycling. Interoceptive abilities were assessed before and after both sessions using a heartbeat-perception and respiratory-load task. Emotional perception was measured using four matched international affective picture system (IAPS) picture sets presented randomly. RESULTS: Active HD-tDCS did not significantly improve interoceptive accuracy, interoceptive emotion evaluation, or interoceptive sensibility. However, a notable increase in cardiac interoceptive awareness was observed after active HD-tDCS. The expected enhancement of emotional processing was not observed. CONCLUSIONS: This study represents the first attempt to modulate interoceptive and emotional processing using HD-tDCS over S1. Although consistent enhancement was not observed, our findings provide insights into the modulation of interoceptive and emotional processes with HD-tDCS, suggesting avenues for further research. Further studies should consider the nuanced effects of stimulation techniques and the complex interplay between interoception and emotion.

Understanding why oral health professionals migrate: A qualitative investigation of Iranian dentists who have moved to Canada (Oral health professionals' migration).

BACKGROUND: The migration of health professionals from Low- and Middle-Income Countries (LMICs) to High-Income countries (HICs) is an ongoing phenomenon that has been accelerating with globalisation. While there has been growing research around the migration of physicians and nurses, there is less understanding of the motives surrounding the migration of dentists, and even less about their migration from specific countries. OBJECTIVES: This qualitative study explores the migration motivations of Iranian dentists who have moved to Canada. METHODS: Semi-structured interviews of 18 Iranian-trained dentists in Canada were conducted to obtain information about their motives for migration. Interviews were coded and categorised into themes using qualitative thematic analysis. RESULTS: Motivations to migrate were grouped into four analytical areas: socio-political; economic; professional; and personal. An inverse relationship was identified between the strongest motives to migrate and the topics respondents were least comfortable discussing. Socio-political-related motives were predominant with respondents focusing on their dissatisfaction with the social ethos and restrictions on personal freedom within Iran. CONCLUSION: Country-specific context is critical to fully understand health professional migration; in particular, the dynamics and interplay between socio-political, economic, and professional/personal factors within the home country. While Iranian dentists' motives to migrate have some similarities to other health professionals who migrated from Iran, and dentists from other countries, differences need to be considered to fully understand migration patterns.

Surgical Practice in the Shadow of COVID-19 Outbreak.

BACKGROUND: COVID-19 epidemic rapidly spread all around the world with over 1500 thousand infected cases and 95000 deaths. This rapid pandemic may overwhelm health care capacity and shortage of resources is a major concern. Literature provided guidelines on management of COVID-19 patients but healthcare service to the normal population should be continued meanwhile. Health system should act immediately and wisely to support essential surgical care while fighting against COVID-19. METHODS: We conducted a comprehensive search in the major data bases since 2020, using the combination of MeSH words of "COVID-19 " and "surgery" and finally 34 full texts entered to data extraction phase to define a plan for surgical practice during COVID-19 pandemic. RESULTS: Healthcare workers are at the higher risk of contamination by COVID-19 especially in early stage of outbreak when they were not aware of the different aspects of COVID-19 pandemic. All healthcare staff must be trained to properly use PPE. All patients have to be screened at the hospital triage. All elective surgical interventions must be postponed. Operation room is considered as a place with high risk of cross infection so the highest level of protection should be maintained. Anesthesia, endoscopy and oral surgery are considered as aerosol producing procedures with very high risk of contamination. There is not any evidence to support the risk of infection trough blood products. Postoperative respiratory problems are more common among COVID-19 patients that may increases the estimated risk of morbidity and mortality. CONCLUSION: COVID-19 pandemic is a dynamic challenge for health system to save the healthcare staff and equipment resources by timely decisions. Healthcare workers are at the higher risk of contamination by COVID-19 especially in early phase of epidemic when the protection is sub-optimal.

"Tie over ring" sutureless compression based gastrointestinal anastomotic method: experimental rat model.

INTRODUCTION: Giving the ever-rising trend of pediatric minimally invasive surgery besides early neonatal surgical interventions, intestinal anastomosis turns out to be a time consuming stage due to several anatomical as well as technical difficulties. A perfect bowel anastomosis method should be easy, rapid, safe and reliable in creation of bowel continuity with minimal tissue damage. In this light, sutureless anastomotic methods have been introduced, using compression based anastomosis with biofragmentable rings or powerful magnets. Accordingly, this experimental animal model study has evaluated the result of an easy, rapid intestinal sutureless anastomotic technique via simple tying over an intraluminal ring, in comparison with conventional handsewn bowel anastomosis. METHODOLOGY: Thirty Wistar-Albino male rats were enrolled and small bowel was transected via a midline laparotomy. A grooved plastic ring was inserted into the ileal lumen and both intestinal cutting ends were fixed over the ring with a simple tie in the first group. On the other hand, enteroenterostomy was performed by the conventional method of handsewn anastomosis in the second group. After 14 days, rats were sacrificed to evaluate for intraperitoneal adhesion and abscess formation in addition to other evidences of anastomotic leakage. Furthermore, the anastomotic site integrity, tensile strength and healing stage were assessed microscopically. RESULTS: The mean operative time and intraoperative bleeding in the tie over ring group were significantly less than those in the handsewn anastomosis group. Anastomotic stricture was more common in the conventional anastomosis group while the anastomotic tensile strength was significantly higher in the tie over ring group. Histopathological healing parameters and final healing score were almost similar in both groups but mean inflammatory cell infiltration in handsewn anastomosis was significantly higher. CONCLUSION: "Tie over ring" is a simple method of anastomosis that is feasible, fast, safe and functionally effective for bowel reconstruction in animal models that could be reconsidered in human bowel anastomosis.

Megacystis microcolon intestinal hypoperistalsis syndrome.

Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a multisystemic disorder in which impaired intestinal motor activity causes recurrent symptoms of intestinal obstruction in the absence of mechanical occlusion, associated with bladder distention without distal obstruction of the urinary tract. MMIHS and prune belly syndrome may overlap in most of the clinical features and discrimination of these two entities is important because the prognosis, management and consulting with parents are completely different. MMIHS outcome is very poor and in this article we present two neonates with MMIHS that both died in a few days.

Evaluation of tooth size in patients with congenitally-missing teeth.

BACKGROUND AND AIMS: Hypodontia is a common developmental abnormality of dentition. This study aimed to determine tooth width in patients affected with mild hypodontia and compare the results with a control group without tooth agenesis. MATERIALS AND METHODS: The orthodontic records of 25 patients with congenital missing of one or two teeth (hypodontia group), and 25 subjects with full dentition (control group) were selected. The greatest mesiodistal width of each tooth was measured on the study models by a digital caliper. Tooth width measurements were compared between the groups using a student t-test at p < 0.05 of significance. RESULTS: Patients with hypodontia showed narrower teeth than the control subjects. The differences in tooth size between the two groups were statistically significant for the first and second premolars and first molar in the maxillary right and for the second premolar in the maxillary left quadrants (p < 0.05). In the lower arch, the first and second premolars and also first molar in both sides of hypodontia patients demonstrated significant reduction in tooth size compared to the control group (p < 0.05). CONCLUSION: These findings suggest that patients with mild hypodontia have narrower teeth than normal subjects especially in posterior segments, which may have clinical implications during the orthodontic treatment process.

A case report of maxillary second molar with two palatal root canals and a furcal enamel pearl.

This case report presents an uncommon case of maxillary molar with two palatal root canals and an enamel pearl in the furcation area. The article discusses root canal complexities of maxillary second molars as well as possibility of coexisting anomalies in the region that makes radiographic interpretation difficult and compromises the success of endodontic treatment.