1.
J Pept Sci
; 20(12): 923-7, 2014 Dec.
Article
in English
| MEDLINE
| ID: mdl-25331328
ABSTRACT
Natural tetrapeptide Goralatide inhibits primitive hematopoietic cell proliferation but reported to be rather unstable in solution (half-life 4.5 min). In this work, we report the synthesis of an aminoxy analog of Goralatide. Aminoxy moiety is expected to provide increased stability and bioavailability of the Goralatide analog.