Selective adaptation in sound lateralization is not due to a repulsion effect.

Selective adaptation studies in dichotic sound lateralization have contributed to a three-channel model of lateralization mechanisms. They usually have employed highly-lateralized adaptor stimuli, and the expression of the selective adaptation is the perceptual shift of test tone locations away from that of the adaptor. The present study employed modestly lateralized adaptors so that any repulsion mechanism could be visualized in distorted position judgments for test tones on both sides of the adaptor stimuli. Comparison of position reports for tones lateralized using interaural time differences before and after selective adaptation provided no evidence for a repulsion effect.

Exploring the experience of nursing home residents participation in a hope-focused group.

A qualitative intervention was used to explore how older adults living in a long-term care environment (nursing home) understand hope and experience being participants in a group in which a hope intervention was carried out. A group project in which each session focused intentionally on a hope strategy was carried out with a convenience sample of 10 women (ages 75-99) who were members of an existing group. Data were analyzed using thematic analysis of the interviews (conducted before the group intervention was carried out and again at the end), field notes, and collaborative conversations regarding emerging themes. Findings from this study suggest that hope is not static and that it can change over time in response to one's situations and circumstances. Also evident in this study is the potential for using a group process in long-term care to foster hope in an intentional way to make it more visible in the lives of the residents and their environment suggesting that one is "never too old for hope."

The three-channel model of sound localization mechanisms: interaural time differences.

Previous psychophysical work on sound localization in humans has proposed that a midline channel be added to the current two-channel model of mammalian sound localization mechanisms. Evidence for this third channel has been found in interaural time difference (ITD) studies with low-frequency tones, and interaural level difference (ILD) studies with both high- and low-frequency tones. The latter is interesting because it suggests that, despite the fact that low frequencies do not generate significant ILDs for humans in natural settings, there is a constancy of ILD coding mechanisms across the frequency domain. To complement this finding, the present study sought to determine whether the three-channel model holds for ITDs at high frequencies. In three experiments, a selective adaptation paradigm was used in combination with transposed tones to probe for the existence of three (left, right, and midline) perceptual channels for sound source azimuth. The experiments provided evidence for lateral hemifield ITD channels but little evidence for a midline ITD channel at high frequencies.

Dual mechanisms in the perceptual processing of click train temporal regularity.

Two experiments measured human sensitivity to temporal jitter in 25-click trains with inter-click intervals (ICIs) between 5 and 100 ms. In a naturalistic experiment using wideband clicks, jitter thresholds were a nonmonotonic function of ICI, peaking for ICIs near 40-60 ms. In a subsequent experiment, clicks were high-passed and presented against a low-frequency noise masker. Jitter threshold vs ICI functions lost the positive slope over short ICIs but retained the negative slope at long ICIs. The same behavior was seen in click rate discrimination tasks. Different processes mediate regularity analysis for click trains with ICIs above and below 40-60 ms.

An asthma action plan created by physician, educator and patient online collaboration with usability and visual design optimization.

BACKGROUND: Asthma action plans (AAPs), which decrease hospitalizations and improve symptom control, are recommended in guidelines, but are seldom delivered to patients. Existing AAPs have been developed by experts, without the inclusion of all stakeholders (such as patients with asthma) and without specifically addressing usability and visual design. OBJECTIVE: Our objective was to develop a more usable AAP by involving all stakeholders and considering design preferences. METHODS: We created a Wiki-based system for multiuser AAP development. Pulmonologists, primary care physicians, asthma educators and patients used the system to collaboratively compile a single AAP by making multiple online selections over 1 week. We combined common elements from 3 AAPs developed in this way into 1, optimized visual design features and tested face validity in focus groups. RESULTS: A total of 41 participants averaged 646 selections/week over a login-time of 28.8 h/week. Of 35 participants, 28 (80%) were satisfied with the final AAP and 32 (91%) perceived that they would be able to use it. The plans created by the 3 groups were very similar, with a unanimous or majority agreement in the handling of 100/110 (91%) AAP options. CONCLUSIONS: Inclusion of multiple stakeholders and focus on design preferences predict enhanced usability and uptake of medical tools. The validity of our AAP is further supported by the similarity between the AAPs created by each group, user engagement and satisfaction with the plan and agreement with existing validity criteria proposed by experts. This AAP can be implemented in care with a concurrent measurement of uptake and health impact.

The three-channel model of sound localization mechanisms: interaural level differences.

The current understanding of mammalian sound localization is that azimuthal (horizontal) position assignments are dependent upon the relative activation of two populations of broadly-tuned hemifield neurons with overlapping medial borders. Recent psychophysical work has provided evidence for a third channel of low-frequency interaural time difference (ITD)-sensitive neurons tuned to the azimuthal midline. However, the neurophysiological data on free-field azimuth receptive fields, especially of cortical neurons, has primarily studied high-frequency cells whose receptive fields are more likely to have been shaped by interaural level differences (ILDs) than ITDs. In four experiments, a selective adaptation paradigm was used to probe for the existence of a midline channel in the domain of ILDs. If no midline channel exists, symmetrical adaptation of the lateral channels should not result in a shift in the perceived intracranial location of subsequent test tones away from the adaptors because the relative activation of the two channels will remain unchanged. Instead, results indicate a shift in perceived test tone location away from the adaptors, which supports the existence of a midline channel in the domain of ILDs. Interestingly, this shift occurs not only at high frequencies, traditionally associated with ILDs in natural settings, but at low frequencies as well.

A midline azimuthal channel in human spatial hearing.

Neurophysiological and psychophysical evidence has driven the formulation of a hemifield model of mammalian sound localization in which the perceived location of a stimulus is based on the relative activity of two hemifield-tuned azimuthal channels that are broadly responsive to contralateral auditory space and have overlapping medial borders. However, neurophysiological work in mammals has consistently found neurons selective for sound sources at the midline, which may indicate the existence of a third, 'midline', perceptual channel. In three experiments, the existence of three (left, right, midline) perceptual channels for azimuth in man was examined using auditory selective adaptation paradigms. If no midline channel exists, exposure to highly lateralized, symmetrical adaptor frequencies should not result in a shift in the perceived intracranial location of subsequent test tones away from the adaptors because the relative activation of the two hemifield channels will remain the same. Rather, our results indicate a shift in perceived test tones towards the azimuthal midline. This result can best be explained by a perceptual/neural channel tuned to sounds located along the midline. The present study gives the first psychophysical evidence of a midline channel serving human auditory localization, adding to the earlier evidence on the same point from animal neurophysiological studies.

Ear and contralateral masker effects on auditory temporal gap detection thresholds.

A temporal processing advantage is thought to underlie the left hemisphere dominance for language. One measure of a temporal processing advantage is temporal acuity or resolution. A standard paradigm for measuring auditory temporal resolution is gap detection in its "within-channel" and "between-channel" forms. Previous experiments investigating a right ear advantage for within-channel gap detection have yielded conflicting results, and between-channel gap detection has not previously been studied for ear differences. In the present study, the two types of gap detection task were employed, under each of three contralateral masking conditions (no noise, continuous noise and interrupted noise). An adaptive tracking procedure was used to measure the minimal detectable gap at each ear (and therefore, the temporal acuity of the contralateral hemisphere). A significant effect of masking noise was observed in both of the gap detection tasks. Within-channel gap threshold durations were longer in the interrupted noise condition for both ears. Between-channel gap threshold durations were shorter in the interrupted noise condition at the left ear, with a trend in the same direction at the right ear. The study found no significant difference between the ears in thresholds in either gap detection task in any of the masking conditions. This suggests that if the left cerebral hemisphere has a temporal processing advantage, then it is not in the form of acuity for temporal gap detection.

Adaptation of central pitch-specific mechanisms.

Three previous psychophysical studies have demonstrated that interaural time difference (ITD) coding mechanisms can undergo frequency-specific, selective adaptation. We sought to determine whether this phenomenon extends to the pitch domain, by employing the same psycho-physical paradigm as one used previously, but with harmonic tone complexes lacking energy at the fundamental frequency. Ten normal listeners participated in experiment 1. Psychometric functions for ITDs were obtained for harmonic tone complexes with fundamental frequencies of 110 Hz and 185 Hz, before and after selective adaptation with complexes of the same fundamental frequencies lateralised to opposite sides. In experiment 1, each subject was tested twice. On separate days, subjects were tested with 110 Hz and 185 Hz stimuli that were either partially resolvable complexes or unresolvable ones. Both partially resolved and unresolved stimuli supported adaptation, and at both fundamental frequencies. In experiment 2, which employed nine listeners, the adaptor tone complexes were presented in conjunction with a diotic noise background designed to mask difference tones generated by the adaptor stimuli. The use of the masker had little effect on the mean strength of the adaptation effected by the unresolved adaptor stimuli, and only slightly weakened the adaptation effect found with the partially resolved adaptor stimuli. Taken together, these data constitute the first demonstration of selective adaptation exerted on a central mechanism in the pitch domain.

The effects of lateralized adaptors on lateral position judgements of tones within and across frequency channels.

Two experiments examined the effect of highly lateralized adaptor tone pulses on the perceived intracranial location of subsequent test tones. In Experiment 1, adaptor tones of each of two frequencies, highly lateralized to opposite sides by a quarter-period interaural time difference (ITD), were found to shift the perceived intracranial location of test tones of each adaptor frequency away from the side of the adaptor. The shift in perceived location was seen for all test tone ITDs with the same sign as the adaptor tone, and sometimes extended to include test tones with small ITDs favoring the opposite ear. The generality of the effect across test tone ITDs of the same sign as the adaptor suggests that the human auditory lateralization system is built of two (left, right) hemifield-tuned azimuthal channels, and that perceived lateral location depends on the relative outputs of those two channels. In Experiment 2, the perceived location of test tones lateralized by ITD was studied in the same listeners at each of the same two frequencies, but after selective adaptation with tone pulses of only one frequency and laterality. The perceived lateral position of test tones with the same frequency as that of the adaptor underwent the same changes as seen in Experiment 1. The perceived lateral position of test tones of the nonadapted frequency usually shifted weakly in the opposite direction, i.e., in the direction expected if the second adaptor from Experiment 1 had actually been present. These data have implications both for the processes mediating selective adaptation using contingent stimuli, and for the azimuthal tuning of auditory spatial channels in man.

Development of perceptual correlates of reading performance.

Performance on perceptual tasks requiring the discrimination of brief, temporally proximate or temporally varying sensory stimuli (temporal processing tasks) is impaired in some individuals with developmental language disorder and/or dyslexia. Little is known about how these temporal processes in perception develop and how they relate to language and reading performance in the normal population. The present study examined performance on 8 temporal processing tasks and 5 language/reading tasks in 120 unselected readers who varied in age over a range in which reading and phonological awareness were developing. Performance on all temporal processing tasks except coherent motion detection improved over ages 7 years to adulthood (p<0.01), especially between ages 7 and 13 years. Independent of these age effects, performance on all 8 temporal processing tasks predicted phonological awareness and reading performance (p<0.05), and three auditory temporal processing tasks predicted receptive language function (p<0.05). Furthermore, all temporal processing measures except within-channel gap detection and coherent motion detection predicted unique variance in phonological scores within subjects, whereas only within-channel gap detection performance explained unique variance in orthographic reading performance. These findings partially support the (Farmer, M.E., Klein, R.M., 1995. The evidence for a temporal processing deficit linked to dyslexia: A review. Psychon. Bull. Rev. 2, 460-493) notion of there being separable auditory and visual perceptual contributions to phonological and orthographic reading development. The data also are compatible with the view that the umbrella term "temporal processing" encompasses fundamentally different sensory or cognitive processes that may contribute differentially to language and reading performance, which may have different developmental trajectories and be differentially susceptible to pathology.

Interaction in the perceptual processing of interaural time and level differences.

Phillips and Hall [Psychophysical evidence for adaptation of central auditory processors for interaural differences in time and level, Hear. Res., 202 (2005) 188-199.] recently described the frequency-specific, selective adaptation of perceptual channels for interaural differences in level (ILD) and time (ITD). Psychometric functions for laterality based on ITD or ILD were obtained before and after exposure to adaptor tones of two frequencies presented alternately and highly lateralized to opposite sides. Following adaptation, points of perceived centrality (PPCs) were displaced towards the sides of the adaptor tones, and in opposite directions for the two frequencies. That is, laterality judgements showed a shift away from the adapted side, particularly for test cue values near the middle of the range. These data were congruent with a two-channel, opponent-process model of sound laterality coding. The present study used the same general paradigm to explore the independence of perceptual ITD and ILD processing. Psychometric functions for laterality based on ITD or ILD were obtained for each of two frequencies concurrently, before and after exposure to adaptor tones lateralized using the complementary cue. Once again, PPCs derived from the psychometric functions were displaced towards the sides of the adaptor tones, consistent with an opponent-process account of sound laterality coding. The size of the adaptation effect was at least as great as that described in the earlier study. Thus, a quarter cycle ITD adapting stimulus effected a 3 dB shift in the mean ILD-based PPC, and a 12 dB ILD adapting stimulus effected a 100 micros shift in the mean ITD-based PPC. These data offer new evidence concerning interaction in the processing of ITDs and ILDs.

Psychophysical evidence for adaptation of central auditory processors for interaural differences in time and level.

Human listeners were studied for their ability to lateralize single target tones of each of two frequencies relative to midline clicks. They did so before and after exposure to adaptor tones of the same frequencies. The adaptor tones were strongly lateralized, and in opposite directions for each frequency, by either an interaural time difference (ITD, Experiment 1) or interaural level difference (ILD, Experiment 2). Following adaptation, psychometric functions for ITD (Exp. 1) and ILD (Exp. 2) were obtained for target tones for the two frequencies separately. These were found to be shifted in the direction of the fatigued side. In the case of ILD, this was in the absence of a shift in monaural sensitivity sufficient to account for the effect. For both ITD and ILD studies, shifts in perceived laterality were induced in opposite directions at two frequencies concurrently. This effect was induced with only seconds of intermittent exposure to the adaptor tones. The fact that it could be induced at two frequencies in opposite directions at the same time, suggests (a), that these data constitute new psychophysical evidence for the frequency specificity of ITD and ILD coding in the human brain, and (b), that the effect was not due to the introduction of some response bias at the decision level of perceptual judgement. The data are interpreted in terms of a two- or three-channel opponent process model.

Detection of static and dynamic changes in interaural correlation.

This study examines the relation between a static and a dynamic measure of interaural correlation discrimination: (1) the just noticeable difference (JND) in interaural correlation and (2) the minimum detectable duration of a fixed interaural correlation change embedded within a single noise-burst of a given reference correlation. For the first task, JNDs were obtained from reference interaural correlations of + 1, -1, and from 0 interaural correlation in either the positive or negative direction. For the dynamic task, duration thresholds were obtained for a brief target noise of +1, -1, and 0 interaural correlation embedded in reference marker noise of +1, -1, and 0 interaural correlation. Performance with a reference interaural correlation of +1 was significantly better than with a reference correlation of -1. Similarly, when the reference noise was interaurally uncorrelated, discrimination was significantly better for a target correlation change towards +1 than towards -1. Thus, for both static and dynamic tasks, interaural correlation discrimination in the positive range was significantly better than in the negative range. Using the two measures, the length of a binaural temporal window was estimated. Its equivalent rectangular duration (ERD) was approximately 86 ms and independent of the interaural correlation configuration.

Spatial stimulus cue information supplying auditory saltation.

Auditory saltation is a misperception of the spatial location of repetitive, transient stimuli. It arises when clicks at one location are followed in perfect temporal cadence by identical clicks at a second location. This report describes two psychophysical experiments designed to examine the sensitivity of auditory saltation to different stimulus cues for auditory spatial perception. Experiment 1 was a dichotic study in which six different six-click train stimuli were used to generate the saltation effect. Clicks lateralised by using interaural time differences and clicks lateralised by using interaural level differences produced equivalent saltation effects, confirming an earlier finding. Switching the stimulus cue from an interaural time difference to an interaural level difference (or the reverse) in mid train was inconsequential to the saltation illusion. Experiment 2 was a free-field study in which subjects rated the illusory motion generated by clicks emitted from two sound sources symmetrically disposed around the interaural axis, ie on the same cone of confusion in the auditory hemifield opposite one ear. Stimuli in such positions produce spatial location judgments that are based more heavily on monaural spectral information than on binaural computations. The free-field stimuli produced robust saltation. The data from both experiments are consistent with the view that auditory saltation can emerge from spatial processing, irrespective of the stimulus cue information used to determine click laterality or location.