1.
Nat Cell Biol
; 22(2): 257, 2020 Feb.
Article
in English
| MEDLINE
| ID: mdl-31969686
ABSTRACT
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
2.
Nat Cell Biol
; 22(1): 7-17, 2020 01.
Article
in English
| MEDLINE
| ID: mdl-31907409
ABSTRACT
Adult haematopoietic stem cells (HSCs) mainly reside in the bone marrow, where stromal and haematopoietic cells regulate their function. The steady state HSC niche has been extensively studied. In this Review, we focus on how bone marrow microenvironment components respond to different insults including inflammation, malignant haematopoiesis and chemotherapy. We highlight common and unique patterns among multiple cell types and their environment and discuss current limitations in our understanding of this complex and dynamic tissue.