ABSTRACT
We report the clinical course of a 48 year old woman, who underwent a cranial MRI-examination in 1995, which confirmed the diagnosis of encephalomyelitis disseminata, but also showed a left temporal venous malformation without evidence of prior hemorrhage. Three month after immunosuppressive treatment with Methotrexate in 1997 begun, first hemorrhage in the left temporal lobe occurred with de novo formation of a cavernoma in association to the known venous malformation. The lesion was totally removed after stereotactic guided craniotomy without any complication. The pathogenetic relationship of de novo cavernomas and associated venous malformations and the remarkable association with immunosuppressive treatment will be discussed.
Subject(s)
Brain Neoplasms/complications , Encephalomyelitis, Acute Disseminated/drug therapy , Hemangioma, Cavernous/complications , Immunosuppressive Agents/therapeutic use , Intracranial Arteriovenous Malformations/complications , Methotrexate/therapeutic use , Brain Neoplasms/diagnosis , Brain Neoplasms/pathology , Brain Neoplasms/surgery , Female , Hemangioma, Cavernous/diagnosis , Hemangioma, Cavernous/pathology , Hemangioma, Cavernous/surgery , Humans , Intracranial Arteriovenous Malformations/diagnosis , Intracranial Arteriovenous Malformations/pathology , Intracranial Arteriovenous Malformations/surgery , Magnetic Resonance Imaging , Middle Aged , Temporal LobeSubject(s)
Exophthalmos/etiology , Fibroma/diagnosis , Nasal Obstruction/etiology , Nasopharyngeal Neoplasms/diagnosis , Papilledema/etiology , Visual Fields/physiology , Adult , Fibroma/pathology , Fibroma/surgery , Humans , Magnetic Resonance Imaging , Male , Nasopharyngeal Neoplasms/pathology , Nasopharyngeal Neoplasms/surgery , Nasopharynx/pathology , Postoperative Complications/diagnosisSubject(s)
Acromegaly/diagnosis , Acromegaly/genetics , Adult , Aged , Diagnosis, Differential , Humans , Male , PedigreeSubject(s)
Cysts/surgery , Meninges/surgery , Spinal Cord Diseases/surgery , Adult , Birth Injuries/complications , Diagnosis, Differential , Epidural Space , Female , Humans , Male , Middle Aged , Spinal Cord Diseases/diagnosis , Spinal Cord Diseases/etiology , Spinal Cord Injuries/complications , Spinal Cord Neoplasms/diagnosisSubject(s)
Brain Injuries/diagnosis , Electroencephalography , Action Potentials , Adult , Aged , Brain Injuries/mortality , Brain Stem/injuries , Cerebral Cortex/injuries , Coma/diagnosis , Coma/mortality , Epilepsy, Post-Traumatic/diagnosis , Evoked Potentials , Female , Growth Hormone/blood , Humans , Hydrocortisone/blood , Male , Mesencephalon/injuries , Middle Aged , Prognosis , Prolactin/bloodABSTRACT
High pressure lumbar air insufflation and endoscopical surgical technique and control improve surgical results and widen indications for the transsphenoidal approach to pituitary adenomas. These complementary methods require a sitting position for the patient and an axial approach to the sella turcica. By lumbar high pressure insufflation even very big pituitary adenomas may often be brought into the operation field and make possible a complete extirpation by a transsphenoidal approach. This possibility is increased by an operative technique under endoscopic control, the latter contributing considerably to complete tumour extirpation, especially with endocrine-active tumours.
Subject(s)
Adenoma/surgery , Pituitary Neoplasms/surgery , Endoscopy , Humans , Methods , Pituitary Neoplasms/diagnosis , Postoperative Care , Preoperative Care , Sphenoid Sinus , Surgical InstrumentsSubject(s)
Neural Conduction , Peripheral Nervous System Diseases/physiopathology , Postgastrectomy Syndromes/physiopathology , Vitamin B 12/blood , Adult , Age Factors , Aged , Female , Follow-Up Studies , Gastrectomy/methods , Humans , Male , Middle Aged , Motor Neurons/physiopathology , Pyramidal Tracts/physiopathology , Time FactorsSubject(s)
Acromegaly/drug therapy , Adenoma, Acidophil/etiology , Bromocriptine/adverse effects , Pituitary Neoplasms/etiology , Adenoma, Acidophil/metabolism , Adenoma, Acidophil/therapy , Female , Growth Hormone/metabolism , Humans , Middle Aged , Pituitary Irradiation , Pituitary Neoplasms/metabolism , Pituitary Neoplasms/therapy , Prolactin/metabolism , Yttrium Radioisotopes/administration & dosageABSTRACT
Basal plasma prolactin levels and values after stimulation with TRH and chlorpromazine respectively were measured. TRH tests were performed in 50 healthy subjects (25 women and 25 men). The basal prolactin levels and the maximum increment were found to be as follows in women 22.02 ng/ml
