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1.
Epidemiol Psychiatr Sci ; 29: e137, 2020 Jun 16.
Article in English | MEDLINE | ID: mdl-32539907

ABSTRACT

AIMS: Although shared decision-making (SDM) has the potential to improve health outcomes, psychiatrists often exclude patients with more severe mental illnesses or more acute conditions from participation in treatment decisions. This study examines whether SDM is facilitated by an approach which is specifically adapted to the needs of acutely ill patients (SDM-PLUS). METHODS: The study is a multi-centre, cluster-randomised, non-blinded, controlled trial of SDM-PLUS in 12 acute psychiatric wards of five psychiatric hospitals addressing inpatients with schizophrenia or schizoaffective disorder. All patients fulfilling the inclusion criteria were consecutively recruited for the trial at the time of their admission to the ward. Treatment teams of intervention wards were trained in the SDM-PLUS approach through participation in two half-day workshops. Patients on intervention wards received group training in SDM. Staff (and patients) of the control wards acted under 'treatment as usual' conditions. The primary outcome parameter was the patients' perceived involvement in decision-making at 3 weeks after study enrolment, analysed using a random-effects linear regression model. RESULTS: In total, 161 participants each were recruited in the intervention and control group. SDM-PLUS led to higher perceived involvement in decision-making (primary outcome, analysed patients n = 257, mean group difference 16.5, 95% CI 9.0-24.0, p = 0.002, adjusted for baseline differences: ß 17.3, 95% CI 10.8-23.6, p = 0.0004). In addition, intervention group patients exhibited better therapeutic alliance, treatment satisfaction and self-rated medication compliance during inpatient stay. There were, however, no significant improvements in adherence and rehospitalisation rates in the 6- and 12-month follow-up. CONCLUSIONS: Despite limitations in patient recruitment, the SDM-PLUS trial has shown that the adoption of behavioural approaches (e.g. motivational interviewing) for SDM may yield a successful application to mental health. The authors recommend strategies to ensure effects are not lost at the interface between in- and outpatient treatment.Trial registration: The trial was registered at Deutsches Register Klinischer Studien (DRKS00010880).


Subject(s)
Decision Making , Inpatients/psychology , Patient Participation , Schizophrenia/therapy , Adult , Communication , Female , Humans , Male , Medication Adherence , Middle Aged , Outcome and Process Assessment, Health Care , Psychiatric Department, Hospital , Schizophrenic Psychology , Young Adult
2.
Epidemiol Psychiatr Sci ; 29: e129, 2020 May 22.
Article in English | MEDLINE | ID: mdl-32438939

ABSTRACT

AIMS: Studies on the frequency of caregiver involvement in representative inpatient samples are scarce. The aim of our study was to conduct a representative survey on caregiver involvement in routine inpatient care involving all three parties (patients, caregivers, psychiatrists). Therefore, we performed face-to-face interviews consisting of open-ended questions to gain a deeper understanding of when and how caregivers are involved in care treatment and to identify which topics are mainly discussed. METHODS: This cross-sectional survey included inpatients from 55 acute psychiatric wards across ten psychiatric hospitals, their treating psychiatrists and, when possible, their caregivers. In total, we performed semi-structured face-to-face interviews with 247 patients, their treating psychiatrists and 94 informal caregivers. Each psychiatrist named the next two to three patients to be discharged. After a patient had given informed consent, the interview was performed by a researcher. In addition, the psychiatrist and, when possible, the primary caregiver identified by the patient, were also interviewed. RESULTS: It was perceived by both patients and psychiatrists that contact between caregiver and psychiatrist had taken place in one-third of the patient cases. Predictors for psychiatrist-caregiver-contact were revealed in the patient's diagnosis (schizophrenia), a lower history of inpatient stays, and the respective hospital. According to psychiatrists the most frequent subjects of discussion with caregivers involved therapeutic issues and organisational and social-psychiatric topics (e.g. work, living and social support). Patients and caregivers stated that psychiatric treatment and the diagnostic classification of the mental illness were the most frequent topics of conversation. For all three groups, the most often cited reason for missed caregiver involvement was the subjective perception that a caregiver was not in fact needed. CONCLUSIONS: Whether or not caregivers were contacted and involved during an inpatient stay strongly depended on the individual hospital. The frequency of involvement of caregivers can certainly be increased by changing processes and structures in hospitals. All three parties (patients, caregivers and psychiatrists) most often stated that the caregiver was not involved in the treatment because they thought it was unnecessary. Evidence demonstrates the positive effect of caregivers' involvement on the therapeutic process but also on the well-being of the caregiver, therefore it is necessary to increase awareness of this evidence among all three interest groups.


Subject(s)
Caregivers/psychology , Decision Making , Inpatients/statistics & numerical data , Professional-Family Relations , Psychiatry , Schizophrenia/therapy , Adult , Cross-Sectional Studies , Female , Hospitalization , Hospitals, Psychiatric , Humans , Middle Aged , Social Support , Surveys and Questionnaires
3.
Nervenarzt ; 89(5): 524-529, 2018 May.
Article in German | MEDLINE | ID: mdl-29327100

ABSTRACT

As a result of a literature-based expert process, this review provides an overview about the principles of palliative care for people with advanced dementia that are relevant for clinical practice. In particular, the indications, impact and aims of palliative care for advanced dementia are described. Life-prolonging measures and management of symptoms at the end of life are discussed. Furthermore, the overview focuses on the legal basis of decision making.


Subject(s)
Dementia , Palliative Care , Decision Making , Humans , Palliative Care/legislation & jurisprudence
4.
Nervenarzt ; 88(9): 995-1002, 2017 Sep.
Article in German | MEDLINE | ID: mdl-28597029

ABSTRACT

BACKGROUND: The concept of shared decision-making (SDM) has existed since the 1990s in multiple fields of somatic medicine but has only been poorly applied in psychiatric clinical routine despite broad acceptance and promising outcomes in clinical studies on its positive effects. MATERIALS AND METHODS: The concept itself and its practicability in mental health are carefully assessed and strategies for its future implementation in psychiatric medicine are presented in this article. Ongoing clinical studies probing some of those strategies are further outlined. RESULTS AND DISCUSSION: On top of the ubiquitous shortage of time in clinical routine, psychiatrists report their concern about patients' limited abilities in sharing decisions and their own fear of potentially harmful decisions resulting from a shared process. Misinterpretation of shared decision-making restricting the health care professional to rather an informed choice scenario and their own adhesion to the traditional paternalistic decision-making approach further add to SDM's underutilization. Those hurdles could be overcome by communication skill workshops for all mental health care professionals, including nursing personnels, psychologists, social workers and physicians, as well as the use of decision aids and training courses for patients to motivate and empower them in sharing decisions with the medical staff. By this, the patient-centered treatment approach demanded by guidelines, carers and users could be further facilitated in psychiatric clinical routine.


Subject(s)
Contraindications, Procedure , Decision Making , Mental Disorders/therapy , Acute Disease , Communication , Germany , Guideline Adherence , Health Plan Implementation , Humans , Mental Disorders/diagnosis , Mental Disorders/psychology , Paternalism , Patient Compliance/psychology , Patient Education as Topic , Personal Autonomy , Physician-Patient Relations
5.
J Environ Manage ; 168: 36-45, 2016 Mar 01.
Article in English | MEDLINE | ID: mdl-26696604

ABSTRACT

Globally, efforts are underway to reduce anthropogenic greenhouse gas emissions and to adapt to climate change impacts at the local level. However, there is a poor understanding of the relationship between city strategies on climate change mitigation and adaptation and the relevant policies at national and European level. This paper describes a comparative study and evaluation of cross-national policy. It reports the findings of studying the climate change strategies or plans from 200 European cities from Austria, Belgium, Estonia, Finland, France, Germany, Ireland, Italy, Netherlands, Spain and the United Kingdom. The study highlights the shared responsibility of global, European, national, regional and city policies. An interpretation and illustration of the influences from international and national networks and policy makers in stimulating the development of local strategies and actions is proposed. It was found that there is no archetypical way of planning for climate change, and multiple interests and motivations are inevitable. Our research warrants the need for a multi-scale approach to climate policy in the future, mainly ensuring sufficient capacity and resource to enable local authorities to plan and respond to their specific climate change agenda for maximising the management potentials for translating environmental challenges into opportunities.


Subject(s)
Cities , Climate Change , Policy Making , Europe , Humans , Urbanization
6.
Epidemiol Psychiatr Sci ; 24(2): 146-9, 2015 Apr.
Article in English | MEDLINE | ID: mdl-24308312

ABSTRACT

AIMS: To study whether employees who disclose a psychiatric diagnosis, such as depression risk stigmatisation and discrimination at the workplace. METHODS: Randomised experimental study with 748 managers from German companies incorporating four case vignettes displaying an employee with different 'diagnoses' (depression, burnout, private crisis and thyroid dysfunction), but identical unspecific complaints. Main outcome measures were the managers' attitudes and their impact on stigmatisation with respect to job performance. RESULTS: In nearly all aspects of job performance, the diagnosis depression (psychiatric disorder) was seen as more critical than the diagnosis of a thyroid dysfunction (somatic disease). The diagnosis 'burnout' did not prove to be less stigmatising than 'depression'. Likewise 'private crisis' was rated less favourably than thyroid dysfunction. CONCLUSIONS: Therefore, employees have to evaluate if they disclose their psychiatric disorder or if they conceal it as a somatic illness.

7.
Pharmacopsychiatry ; 47(3): 84-8, 2014 May.
Article in English | MEDLINE | ID: mdl-24652700

ABSTRACT

INTRODUCTION: Depression, anxiety, agitation and sleep disorders are highly prevalent in the general population, but few persons receive psychiatric care. METHODS: Our aim was to study the views of 690 German pharmacists on "over-the counter" (OTC) drugs for these indications. RESULTS: They reported dispensing OTC medication to an average of 12 customers per day, and this corresponded to almost one quarter of the medications provided for these indications. Herbal drugs and complex homeopathic formulations were used most frequently. Patients preferring OTC substances were described as being younger, with shorter durations of illness and less severe symptoms, and more skeptical regarding psychopharmacology. While genuine pharmacological effects were considered as most relevant, pharmacists were highly aware of placebo and interpersonal factors. Symptoms, comorbidity and advice on drug intake were prominent topics during pharmacy consultations. CONCLUSION: German pharmacists report dispensing large amounts of OTC drugs for anxiety, agitation, sleep disturbances or depression. It is unclear whether this constitutes a rational and cost effective method to deal with mild courses of high prevalence diseases or must be seen critically.


Subject(s)
Anxiety Disorders/drug therapy , Attitude of Health Personnel , Mood Disorders/drug therapy , Nonprescription Drugs/therapeutic use , Pharmacists/psychology , Adult , Aged , Data Collection , Female , Germany , Humans , Male , Middle Aged , Young Adult
8.
Nervenarzt ; 84(7): 838-43, 2013 Jul.
Article in German | MEDLINE | ID: mdl-23715921

ABSTRACT

BACKGROUND: Currently there is much debate about the concept of burnout and its use as a diagnostic entity. The aim of the present survey was to present the view of mental health professionals towards the concept of burnout. METHODS: A total of 300 mental health professionals were surveyed using a structured questionnaire. RESULTS: The majority of participants see burnout as a state of exhaustion which constitutes a risk factor for later developing a mental disorder. Participants reported that from their point of view typical triggers for burnout exist while symptoms overlap to a great extent with depression. Psychotherapy as well as interventions at the workplace are regarded as promising interventions; however, in the clinical routine only a minority of participants actually contacted the patients' workplace. In the participants workplace settings most Burnout-Patients suffered from a diagnosis defined in ICD 10 but judged themselves to be suffering from burnout. DISCUSSION: Burnout-Patients in mental health settings differ from the picture currently drawn in the media, probably because Burnout-Patients reach the mental health sector only after already having developed a manifest psychiatric disorder.


Subject(s)
Attitude of Health Personnel , Burnout, Professional/classification , Burnout, Professional/diagnosis , Occupational Diseases/classification , Occupational Diseases/diagnosis , Psychiatry/statistics & numerical data , Terminology as Topic , Workplace/statistics & numerical data , Adult , Burnout, Professional/psychology , Female , Germany/epidemiology , Humans , Male , Middle Aged , Occupational Diseases/psychology
9.
Bone ; 55(1): 150-7, 2013 Jul.
Article in English | MEDLINE | ID: mdl-23454488

ABSTRACT

Hypophosphatasia (HPP) is a heterogeneous rare, inherited disorder of bone and mineral metabolism caused by different mutations in the ALPL gene encoding the isoenzyme, tissue-nonspecific alkaline phosphatase (TNAP). Prognosis is very poor in severe perinatal forms with most patients dying from pulmonary complications of their skeletal disease. TNAP deficiency, however, may also result in neurological symptoms such as neonatal seizures. The exact biological role of TNAP in the human brain is still not known and the pathophysiology of neurological symptoms due to TNAP deficiency in HPP is not understood in detail. In this report, we describe the clinical features and functional studies of a patient with severe perinatal HPP which presented with rapidly progressive encephalopathy caused by new compound heterozygous mutations in the ALPL gene which result in a functional ALPL "knock out", demonstrated in vitro. In contrast, an in vitro simulation of the genetic status of his currently asymptomatic parents who are both heterozygous for one mutation, showed a residual in vitro AP activity of above 50%. Interestingly, in our patient, the fatal outcome was due to progressive encephalopathy which was refractory to antiepileptic therapy including pyridoxine, rather than hypomineralization and respiratory insufficiency often seen in HPP patients. The patient's cranial MRI showed progressive cystic degradation of the cortex and peripheral white matter with nearly complete destruction of the cerebrum. To our knowledge, this is the first MRI-based report of a deleterious neurological clinical outcome due to a progressive encephalopathy in an infant harboring a functional human ALPL "knock out". This clinical course of disease suggests that TNAP is involved in development and may be responsible for multiple functions of the human brain. According to our data, a certain amount of residual TNAP activity might be mandatory for normal CNS function in newborns and early childhood.


Subject(s)
Alkaline Phosphatase/genetics , Brain Diseases/genetics , Genetic Association Studies , Genetic Predisposition to Disease , Heterozygote , Hypophosphatasia/genetics , Mutation/genetics , Fatal Outcome , HEK293 Cells , Humans , Hypophosphatasia/enzymology , Infant , Infant, Newborn , Magnetic Resonance Imaging , Male , Mutant Proteins/metabolism , Protein Transport , Subcellular Fractions/enzymology
10.
J Immunol Methods ; 375(1-2): 196-206, 2012 Jan 31.
Article in English | MEDLINE | ID: mdl-22075274

ABSTRACT

BACKGROUND: Polarization of macrophages by specific micro-environmental conditions impacts upon their function following subsequent activation. This study aimed to systematically validate robust phenotypic markers for in vitro polarized human macrophages in order to facilitate the study of macrophage subsets in vivo. METHODS: Human peripheral blood monocytes were polarized in vitro with IFN-γ, IL-4, or IL-10. Similar experiments were performed with TNF, IL-13, dexamethasone, M-CSF and GM-CSF as polarizing stimuli. Phenotypic markers were assessed by flow cytometry and qPCR. RESULTS: IFN-γ polarized macrophages (MΦ(IFN-γ)) specifically enhanced membrane expression of CD80 and CD64, IL-4 polarized macrophages (MΦ(IL-4)) mainly upregulated CD200R and CD206, and downregulated CD14 levels, and IL-10 polarized macrophages (MΦ(IL-10)) selectively induced CD163, CD16, and CD32. The expression profiles of the most specific markers were confirmed by qPCR, dose-response experiments, and the use of alternative polarizing factors for each macrophage subset (TNF, IL-13, and dexamethasone, respectively). GM-CSF polarized macrophages (MΦ(GM-CSF)) upregulated CD80 but not CD64 expression, showing a partial phenotypic similarity with MΦ(IFN-γ), and also upregulated the expression of the alternative activation marker CD206. M-CSF polarized macrophages (MΦ(M-CSF)) not only expressed increased levels of CD163 and CD16, resembling MΦ(IL-10,) but also displayed high levels of CD64. The phenotype of MΦ(M-CSF) could be further modulated by additional polarization with IFN-γ, IL-4, or IL-10, whereas MΦ(GM-CSF) showed less phenotypic plasticity. CONCLUSION: This study validated CD80 as the most robust phenotypic marker for human MΦ(IFN-γ), whereas CD200R was upregulated and CD14 was specifically downregulated on MΦ(IL-4). CD163 and CD16 were found to be specific markers for MΦ(IL-10). The GM-CSF/M-CSF differentiation model showed only a partial phenotypic similarity with the IFN-γ/IL-4/IL-10 induced polarization.


Subject(s)
Antigens, CD/genetics , Antigens, CD/metabolism , Cell Differentiation/physiology , Cell Polarity/physiology , Macrophages/cytology , Macrophages/metabolism , Biomarkers/metabolism , Cell Differentiation/genetics , Cell Polarity/genetics , Dexamethasone/pharmacology , Flow Cytometry/methods , Granulocyte-Macrophage Colony-Stimulating Factor/metabolism , Humans , Interferon-gamma/metabolism , Interleukins/metabolism , Macrophage Colony-Stimulating Factor/metabolism , Monocytes/metabolism , Phenotype , Real-Time Polymerase Chain Reaction/methods , Tumor Necrosis Factor-alpha/metabolism
11.
Psychol Med ; 41(12): 2651-9, 2011 Dec.
Article in English | MEDLINE | ID: mdl-21733217

ABSTRACT

BACKGROUND: Diagnostic errors can have tremendous consequences because they can result in a fatal chain of wrong decisions. Experts assume that physicians' desire to confirm a preliminary diagnosis while failing to seek contradictory evidence is an important reason for wrong diagnoses. This tendency is called 'confirmation bias'. METHOD: To study whether psychiatrists and medical students are prone to confirmation bias and whether confirmation bias leads to poor diagnostic accuracy in psychiatry, we presented an experimental decision task to 75 psychiatrists and 75 medical students. RESULTS: A total of 13% of psychiatrists and 25% of students showed confirmation bias when searching for new information after having made a preliminary diagnosis. Participants conducting a confirmatory information search were significantly less likely to make the correct diagnosis compared to participants searching in a disconfirmatory or balanced way [multiple logistic regression: odds ratio (OR) 7.3, 95% confidence interval (CI) 2.53-21.22, p<0.001; OR 3.2, 95% CI 1.23-8.56, p=0.02]. Psychiatrists conducting a confirmatory search made a wrong diagnosis in 70% of the cases compared to 27% or 47% for a disconfirmatory or balanced information search (students: 63, 26 and 27%). Participants choosing the wrong diagnosis also prescribed different treatment options compared with participants choosing the correct diagnosis. CONCLUSIONS: Confirmatory information search harbors the risk of wrong diagnostic decisions. Psychiatrists should be aware of confirmation bias and instructed in techniques to reduce bias.


Subject(s)
Bias , Diagnostic Errors/psychology , Mental Disorders/diagnosis , Psychiatry/statistics & numerical data , Students, Medical/psychology , Adult , Diagnostic Errors/statistics & numerical data , Female , Humans , Male , Psychiatry/standards , Students, Medical/statistics & numerical data , Young Adult
12.
Eur Psychiatry ; 26(5): 297-301, 2011.
Article in English | MEDLINE | ID: mdl-20570493

ABSTRACT

OBJECTIVE: Despite good clinical evidence, depot antipsychotics are only seldom prescribed to patients with first episode schizophrenia. The present study aims at investigating psychiatrists' reasons for this reservation. METHOD: We surveyed 198 psychiatrists on their attitude toward offering depot treatment to first episode patients (FEP). Participants scored the extent of influence of individual factors on their decision on a seven-point-scale, additional data on their prescription practice and estimation of the relapse risk of FEP were collected. RESULTS: Psychiatrists reported that only three out of 12 factors were of influence. These were the limited availability of different second generation antipsychotic depot drugs, the frequent rejection of the depot offer by the patients and the patients' skepticism based on the lack in experience of a relapse. CONCLUSIONS: There is actually little specific reason for not prescribing depot to FEP according to the current survey. For those factors being reported to be of influence, psychoeducation, including profound information on depot treatment, the development of additional SGA depot drugs and the standard offer of depot treatment to all FEP in a shared-decision-making may be considered.


Subject(s)
Antipsychotic Agents/administration & dosage , Attitude of Health Personnel , Psychiatry , Schizophrenia/drug therapy , Adult , Antipsychotic Agents/therapeutic use , Female , Health Care Surveys , Humans , Male , Middle Aged
14.
Eur Radiol ; 20(12): 2917-24, 2010 Dec.
Article in English | MEDLINE | ID: mdl-20625737

ABSTRACT

AIMS: To compare in vivo DNA lesions induced during helical and sequential coronary computed tomography angiography (CTA) and to evaluate the effect of CT parameters on double-strand break (DSB) levels. METHODS: Thirty-six patients were examined with various CT protocols and modes (helical scan, n = 27; sequential scan, n = 9) either using a 64-slice dual-source or a 128-slice CT system. Blood samples were obtained before and 30 min after CT. Lymphocytes were isolated, stained against the phosphorylated histone variant γ-H2AX, and DSBs were visualised by using fluorescence microscopy. RESULTS: DSB yields 30 min after CTA ranged from 0.04 to 0.71 per cell and showed a significant correlation to DLP (ρ = 0.81, p < 0.00001). Median DSB yield and median DLP were significantly lower after sequential compared to helical CT examinations (0.11 vs. 0.37 DSBs/cell and 249 vs. 958 mGy cm, p < 0.00001). Additional calcium scoring led to an increase in DLP (p = 0.15) and DSB levels (p = 0.04). DSB levels normalised to the DLP showed a significant correlation to the attenuation of the blood (ρ = 0.53, p = 0.01) and a negative correlation to the body mass index of the patients (ρ = -0.37, p = 0.06). CONCLUSION: γ-H2AX immunofluorescence microscopy allows one to determine dose-related effects on x-ray-induced DSB levels and to consider individual factors which cannot be monitored by physical dose measurements.


Subject(s)
Biological Assay/methods , Coronary Angiography/methods , DNA Damage , DNA/radiation effects , Lymphocytes/physiology , Lymphocytes/radiation effects , Tomography, X-Ray Computed/methods , Female , Humans , Male , Radiation Dosage
15.
Physiol Res ; 59(3): 331-338, 2010.
Article in English | MEDLINE | ID: mdl-19681660

ABSTRACT

The purpose of this study was to determine if there is flow-mediated vasodilation of the femoral artery in response to progressive increases in flow within a physiological range observed in the in vivo experiments. Femoral artery blood flow was determined in conscious rabbits (n = 5) using chronically implanted flowprobes. Resting blood flow was 8.3 +/- 0.6 ml/min and increased to 39.9 +/- 5.4 ml/min during high intensity exercise. Femoral arteries (n = 12, 1705 +/- 43 microm outer diameter) harvested from a separate group of rabbits were mounted on cannulas and diameter was continuously monitored by video system. Functional integrity of the endothelium was tested with acetylcholine. The arteries were set at a transmural pressure of 100 mm Hg and preconstricted with phenylephrine to 73 +/- 3% of initial diameter. Using a roller pump with pressure held constant, the arteries were perfused intraluminally with warmed, oxygenated Krebs' solution (pH = 7.4) over a physiological range of flows up to 35 ml/min. As flow increased from 5 ml/min to 35 ml/min, diameter decreased significantly (p < 0.05) from 1285 +/- 58 microm to 1100 +/- 49 microm. Thus, in vessels with a functional endothelium, increasing intraluminal flow over a physiological range of flows produced constriction, not dilation. Based on these results, it seems unlikely that flow-mediated vasodilation in the rabbit femoral artery contributes to exercise hyperemia.


Subject(s)
Femoral Artery/physiopathology , Hyperemia/physiopathology , Muscle, Skeletal/blood supply , Physical Exertion , Vasodilation , Acetylcholine/pharmacology , Adaptation, Physiological , Animals , Blood Flow Velocity , Blood Pressure , Femoral Artery/drug effects , Rabbits , Regional Blood Flow , Vasoconstriction , Vasodilation/drug effects , Vasodilator Agents/pharmacology
16.
Acta Psychiatr Scand ; 120(2): 112-9, 2009 Aug.
Article in English | MEDLINE | ID: mdl-19236315

ABSTRACT

OBJECTIVE: In order to choose the best treatment option, physicians have to inform themselves and their patients about both the benefits and risks of available treatment options equally. Our study aims to investigate whether psychiatrists actually do conduct such a balanced information search and presentation. METHOD: Psychiatrists' information search and information presentation to a patient with schizophrenia were studied using two separate experiments. In both, participants were presented with hypothetical case vignettes and descriptions of fictitious antipsychotics. RESULTS: When searching for information, psychiatrists looked more for risks than benefits of antipsychotic treatment options (t = -3.4, df = 74, P = 0.001). However, when informing a patient, they named more benefits than risks (t = 17.1, df = 224, P < 0.001). CONCLUSION: The risk-biased information search presumably follows the principle of 'primum non nocere'. The benefit-biased information presentation might be motivated by the wish to persuade patients to accept the proposed therapy.


Subject(s)
Antipsychotic Agents/adverse effects , Clinical Competence , Disclosure , Patient Education as Topic , Physician-Patient Relations , Psychiatry , Schizophrenia/drug therapy , Adult , Antipsychotic Agents/therapeutic use , Female , Humans , Male , Middle Aged , Risk Factors , Surveys and Questionnaires
17.
Acta Psychiatr Scand ; 114(4): 265-73, 2006 Oct.
Article in English | MEDLINE | ID: mdl-16968364

ABSTRACT

OBJECTIVE: Patients' participation in treatment planning is being increasingly advocated in mental health. The model of "Shared Decision Making" (SDM) is proposed as a promising method of engaging patients in medical decisions and improving health-related outcomes. In the present study, the feasibility and effects of SDM for in-patients with schizophrenia should be evaluated. METHOD: Randomized controlled trial comparing a SDM program with routine care (n = 107). RESULTS: The intervention studied was feasible for most of the patients and did not take up more of the doctors' time. Patients in the intervention group had a better knowledge about their disease (P = 0.01) and a higher perceived involvement in medical decisions (P = 0.03). The intervention increased the uptake of psychoeducation (P = 0.003). CONCLUSION: Sharing medical decisions with acutely ill in-patients with schizophrenia is in many cases possible and improves important treatment patterns. This might help in destigmatizing this group of patients and improving schizophrenia-related health outcomes.


Subject(s)
Cooperative Behavior , Decision Making , Health Planning/statistics & numerical data , Patient Participation/statistics & numerical data , Schizophrenia/epidemiology , Schizophrenia/rehabilitation , Acute Disease , Adolescent , Adult , Aged , Feasibility Studies , Female , Health Education , Hospitalization , Hospitals, State , Humans , Male , Middle Aged , Personal Autonomy , Psychiatric Department, Hospital , Surveys and Questionnaires
18.
Surgeon ; 4(1): 11-3, 2006 Feb.
Article in English | MEDLINE | ID: mdl-16459494

ABSTRACT

INTRODUCTION: Several options exist with regard to flexible pharyngo-laryngoscope sterilisation. We audited the use of disposable sheaths in our department over a six-month period. METHODS: A cost-analysis was performed and the advantages and disadvantages of this system were compared with several alternative options. RESULTS: We found that the overall cost of disposable sheaths averaged l4008 per month over a six-month period. We subsequently introduced chlorine dioxide (ClO2) wipes as a means of disinfection. Chlorine dioxide wipes have enabled a monthly saving of l3145 over sheath usage. Additionally, they meet health regulation requirements and are a convenient, cost-effective alternative to sheaths. DISCUSSION: The limiting factors, including time and financial issues, involved in nasendoscope disinfection are discussed. CONCLUSIONS: We have found chlorine dioxide wipes to be a satisfactory alternative means of nasendoscope disinfection. Possible time constraints aside, there are no advantages of sheath use over our current method. Chlorine dioxide wipes are also preferable from a financial point of view.


Subject(s)
Disinfection/economics , Disinfection/methods , Laryngoscopes/microbiology , Medical Audit , Cost Savings , Cost-Benefit Analysis , Disposable Equipment , Equipment Contamination/prevention & control , Humans , Laryngoscopes/economics , Laryngoscopy , United Kingdom
19.
Nervenarzt ; 77(9): 1071-6, 1078, 2006 Sep.
Article in German | MEDLINE | ID: mdl-15954015

ABSTRACT

Involving patients in medical decisions is increasingly being advocated in medical fields other than psychiatry and neurology. A model of shared decision making might prove to be an ideal way of bridging the gap between patient-centred and evidence-based medicine. This report provides a survey of this shared decision making model and a discussion of its implications in the fields of mental health and neurology.


Subject(s)
Decision Making , Mental Disorders/rehabilitation , Multiple Sclerosis/rehabilitation , Patient Participation/psychology , Schizophrenia/rehabilitation , Substance-Related Disorders/rehabilitation , Adaptation, Psychological , Evidence-Based Medicine , Humans , Mental Disorders/diagnosis , Mental Disorders/psychology , Multiple Sclerosis/diagnosis , Multiple Sclerosis/psychology , Patient Participation/methods , Patient-Centered Care , Personal Autonomy , Psychotherapy , Psychotropic Drugs/therapeutic use , Schizophrenia/diagnosis , Schizophrenic Psychology , Sick Role , Substance-Related Disorders/diagnosis , Substance-Related Disorders/psychology
20.
Article in German | MEDLINE | ID: mdl-15490085

ABSTRACT

The German Ministry for Health and Social Security is funding ten projects to introduce shared decision making into clinical practice. The medical problems the projects are focussing on were chosen from among various diseases (e. g. depression, multiple sclerosis, cancer). The ten projects achieved consensus on a core set of instruments for the measurement of process and outcome of the shared decision making. Instruments developed in German-speaking countries are currently not available. Thus, linguistic and cultural validation had to be performed for the core set instruments. The results of the data analysis as well as patient interviews demonstrate the need for improving these instruments. Therefore, the members of the methodological working group concentrated on the integration of these results in a new instrument. In a first step the construct of "shared decision making" was defined, followed by a definition of the process elements characterising shared decision making. Thereafter, items were developed on the basis of the process elements. The new instrument will now be validated for different diseases.


Subject(s)
Decision Making , Patient Participation , Physician-Patient Relations , Surveys and Questionnaires , Humans , Risk Factors
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