ABSTRACT
BACKGROUND: Full-thickness skin grafts on the dorsum of the nose may heal depressed and might benefit from elevation. Microlipoinjection has been used to elevate depressed tissue; however, the long-term persistence of the augmentation is questioned. OBJECTIVE: To determine whether microlipoinjection beneath depressed full-thickness grafts on the dorsum of the nose can provide effective and persistent graft elevation. METHODS: Microlipoinjection was performed at one to three sessions under depressed full-thickness skin grafts on the nose of four patients. Their appearance was assessed clinically and photographically for the amount of correction at their last postmicrolipoinjection visit. RESULTS: All four patients had clinically significant elevation of their full-thickness skin graft. In the two patients followed for over 3 years, significant augmentation persisted. CONCLUSION: Microlipoinjection can provide cosmetically useful soft tissue augmentation under depressed full-thickness skin grafts; this augmentation can persist.
Subject(s)
Adipose Tissue/transplantation , Microinjections , Nose Deformities, Acquired/surgery , Nose/surgery , Skin Transplantation/adverse effects , Aged , Carcinoma, Basal Cell/surgery , Female , Humans , Male , Middle Aged , Nose Deformities, Acquired/etiology , Nose Neoplasms/surgeryABSTRACT
Clinical trials of PDWHF are ongoing and the final results are not yet available; however early lessons learned have allowed us to modify these trials. It is anticipated that the patient accrual will be completed within the next six months, and the last patient will complete the trial within the next year. At that time, we hope to have new insight into the role of PDWHF in the treatment of lower extremity ulcers. At this time, we are encouraged by the early improvement seen in patients entering the PDWHF versus saline trial. Preliminary results suggest that PDWHF improves the healing of diabetic ulcers of the lower extremity.
Subject(s)
Blood Platelets , Growth Substances/therapeutic use , Leg Ulcer/therapy , Wound Healing , Chronic Disease , Diabetic Neuropathies/complications , Double-Blind Method , Humans , Leg Ulcer/etiology , Prospective StudiesABSTRACT
An ultrasonically vibrating knife has been developed for producing surgical incisions with reduced hemorrhage. Tissue injury and wound healing of porcine cutaneous incisions produced by this instrument, conventional scalpel, electrosurgery, and CO2 laser were compared regarding clinical, histopathologic, and tensile strength differences. Scalpel incisions had the least tissue injury and fastest healing, but the ultrasonically vibrating knife produced less tissue injury and faster healing than electrosurgery or CO2 laser.
