ABSTRACT
We report the results of fecal parasite surveillance in dogs surrendered to the Regina Humane Society, Saskatchewan, Canada, between May and November 2013. Overall, 23% of 231 dogs were infected with at least 1 intestinal parasite. Endoparasite infection was positively associated with rural origin (P = 0.002) and age (< 12 months; P < 0.001).
Origine rurale, âge et prévalence des endoparasites fécaux chez les chiens livrés à la Regina Humane Society, 2013. Nous rapportons les résultats de la surveillance de parasites fécaux chez les chiens livrés à la Regina Humane Society (Saskatchewan, Canada) entre mai et novembre 2013. En tout, 23 % des 231 chiens ont été infectés avec au moins un parasite intestinal. L'infection aux endoparasites a été positivement associée à une origine rurale (P = 0,002) et à l'âge (< 12 mois; P < 0,001).(Traduit par Emilie Bouchard).
Subject(s)
Animal Welfare/statistics & numerical data , Dog Diseases/epidemiology , Parasitic Diseases, Animal/epidemiology , Age Factors , Animals , Dog Diseases/parasitology , Dogs , Feces/parasitology , Female , Male , Parasitic Diseases, Animal/parasitology , Prevalence , Rural Population/statistics & numerical data , Saskatchewan/epidemiologyABSTRACT
Ischemia followed by reperfusion leads to release of toxic molecules into the circulation, and these molecules may cause injury in remote organs such as the lung. Horses commonly suffer from episodes of intestinal ischemia-reperfusion (IR) due to intestinal twisting/strangulation followed by repair. Because there is no evidence of lung injury associated with IR in horses, we designed a study to characterize the intestinal IR-associated lung inflammation and determine the effect of lidocaine on lung inflammation in IR horses. Lung tissues were collected from non-anesthetized (n=4) and anesthetized (n=4) control horses and horses (n=12) after 70 minutes of ischemia followed by 60 minutes of reperfusion. Horses in IR groups received Lactated Ringer's Solution (LRS; n=6) or lidocaine (n=6) intravenously. Control lungs had normal histology but lungs from IR horses showed moderate accumulation of neutrophils in blood vessels and airways. We found increased staining for TLR4, IL-8, TLR9, and von Willebrand factor (vWF) along with aggregates of vWF-positive platelets in lung vessels of IR horses compared to the controls. Lung TNFα was significantly increased in IR horses compared to the control horses (P<0.05). Neutrophil numbers, but not MPO concentrations, were significantly lower, while macrophage numbers were higher in the IR group receiving lidocaine compared to the LRS horses (P<0.05). We conclude that intestinal IR leads to remote lung injury characterized by recruitment of inflammatory cells and expression of inflammatory molecules in horses, and lidocaine may ameliorate lung inflammation following intestinal IR.
