Subject(s)
Indomethacin/therapeutic use , Polyhydramnios/drug therapy , Acute Disease , Adult , Female , Humans , Pregnancy , Recurrence , Uterine Contraction/drug effectsSubject(s)
Anesthesia, Obstetrical/methods , Nerve Block/methods , Female , Humans , Perineum/innervation , PregnancyABSTRACT
The results of a prospective investigation into the reliability of amnioscopy in the detection of meconium staining of the liquor amnii is presented. Under the conditions which prevail in most obstetric units, amnioscopy was found to be an unreliable method of detecting meconium staining of the liquor amnii. False-positive findings are infrequent but false-negative findings are common.
Subject(s)
Amniotic Fluid/analysis , Fetoscopy , Meconium/analysis , Amnion/surgery , Cervix Uteri , Dilatation , False Negative Reactions , False Positive Reactions , Female , Humans , Labor, Induced , Labor, Obstetric , PregnancySubject(s)
Amniotic Fluid/analysis , Prostaglandins/analysis , Cesarean Section , Female , Gestational Age , Humans , Labor, Induced , Labor, Obstetric , Pregnancy , RadioimmunoassaySubject(s)
Embolism, Fat/etiology , Hysterosalpingography/adverse effects , Retinal Diseases/etiology , Adult , Edema/drug therapy , Edema/etiology , Embolism, Fat/drug therapy , Female , Humans , Iodized Oil , Lung/diagnostic imaging , Macula Lutea , Ophthalmoscopy , Prednisolone/therapeutic use , Retinal Diseases/drug therapy , Visual AcuityABSTRACT
PIP: Prostaglandins stimulate myometrial activity in late pregnancy and are also used for induction of labor. The present study analyzed the level of prostaglandin F2alpha (PGF2a) in peripheral plasma in relation to uterine contraction. Blood samples from 10 patients in the first stage of normal labor were collected and assayed. Preliminary studies conducted on 2 groups (group 1, n=4; group 2, n=6) utilized a continuous sampling technique spanning uterine contractions. Substantial and rapid fluctuations in the concentration of PGF2a in peripheral blood during normal labor were observed. Maximum concentrations in the antecubital vein were seen in most cases 15 to 45 seconds after the peak of a uterine contraction. The observed fluctuations were attributed either to intermittent prostaglandin formation, possibly causing uterine contraction, or to intermittent release resulting from uterine contractions. Collection of more exact data, possibly by serial sampling of blood from uterine veins, is needed and should be correlated with observations on other humoral agents which initiate or influence uterine contractility.^ieng
