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1.

Leukemia in donor cells after allogeneic hematopoietic stem cell transplant.

Brunstein, C G; Hirsch, B A; Hammerschmidt, D; McGlennen, R C; Nguyen, P L; Verfaillie, C M.

Bone Marrow Transplant ; 29(12): 999-1003, 2002 Jun.

Article in English | MEDLINE | ID: mdl-12098070

ABSTRACT

The development of leukemia in donor cells after allogeneic hematopoietic stem cell transplant is an extremely rare event. We report here the case of a patient who developed myelodysplastic syndrome/acute myeloid leukemia, in cells of donor origin 3.5 years after related donor HSCT for refractory chronic lymphocytic leukemia and therapy-induced myelodysplastic syndrome. The origin of the leukemia was determined by analysis of minisatillite polymorphism tested on CD34(+) cells.

Subject(s)

Hematopoietic Stem Cell Transplantation , Leukemia, Lymphocytic, Chronic, B-Cell/therapy , Leukemia, Myeloid/genetics , Neoplasms, Second Primary/genetics , Adult , Cell Transformation, Neoplastic/genetics , Cell Transformation, Neoplastic/pathology , Cytogenetic Analysis , Fatal Outcome , Humans , Leukemia, Lymphocytic, Chronic, B-Cell/pathology , Leukemia, Myeloid/etiology , Leukemia, Myeloid/pathology , Male , Minisatellite Repeats , Myelodysplastic Syndromes/pathology , Myelodysplastic Syndromes/therapy , Neoplasms, Second Primary/etiology , Neoplasms, Second Primary/pathology , Tissue Donors , Transplantation Chimera/genetics , Transplantation, Homologous

2.

Sulphur bitters.

Hammerschmidt, D E.

J Lab Clin Med ; 138(3): 215-6, 2001 Sep.

Article in English | MEDLINE | ID: mdl-11548741

Subject(s)

Advertising/history , Famous Persons , Gastrointestinal Agents/history , Nonprescription Drugs/history , Sulfur/history , History, 19th Century , History, 20th Century

3.

Tissue factor expression in sickle cell anemia.

Hammerschmidt, D E.

J Lab Clin Med ; 137(6): 440, 2001 Jun.

Article in English | MEDLINE | ID: mdl-11388349

Subject(s)

Anemia, Sickle Cell/metabolism , Endothelium, Vascular/metabolism , Lung/metabolism , Thromboplastin/metabolism , Anemia, Sickle Cell/complications , Anemia, Sickle Cell/pathology , Endothelium, Vascular/pathology , Fatal Outcome , Female , Humans , Immunohistochemistry , Lung/blood supply , Lung/pathology , Middle Aged , Pulmonary Embolism/etiology , Pulmonary Embolism/pathology , Vascular Cell Adhesion Molecule-1/metabolism

4.

Annulus senilis.

Hammerschmidt, D E.

J Lab Clin Med ; 138(6): 404, 2001 Dec.

Article in English | MEDLINE | ID: mdl-11774875

Subject(s)

Arcus Senilis , Cornea/pathology , Adult , Arcus Senilis/etiology , Arteriosclerosis/complications , Female , Humans , Hyperlipidemias/complications , Male , Middle Aged

5.

Porphyria cutanea tarda.

Hammerschmidt, D E.

J Lab Clin Med ; 136(6): 490, 2000 Dec.

Article in English | MEDLINE | ID: mdl-11128752

Subject(s)

Porphyria Cutanea Tarda/pathology , Estrogen Replacement Therapy/adverse effects , Humans , Menopause , Porphyria Cutanea Tarda/etiology , Risk Factors

6.

Adenomatous polyp of the colon.

Hammerschmidt, D E.

J Lab Clin Med ; 136(3): 252, 2000 Sep.

Article in English | MEDLINE | ID: mdl-10985505

Subject(s)

Adenomatous Polyps , Colonic Polyps , Colonoscopy , Humans

7.

About the cover illustration: crop duster at work near homestead, Florida.

Hammerschmidt, D E.

J Lab Clin Med ; 136(2): 164, 2000 Aug.

Article in English | MEDLINE | ID: mdl-10945245

Subject(s)

Pesticides/adverse effects , Crops, Agricultural , Florida , Humans

8.

Prometheus.

Hammerschmidt, D E.

J Lab Clin Med ; 135(6): 498, 2000 Jun.

Article in English | MEDLINE | ID: mdl-10850650

Subject(s)

Liver Regeneration , Mythology , Stem Cells , Greek World , History, Ancient , Medicine in the Arts , Sculpture

9.

Ethical and practical problems in studying prayer.

Hammerschmidt, D E.

Arch Intern Med ; 160(12): 1874; author reply 1877-8, 2000 Jun 26.

Article in English | MEDLINE | ID: mdl-10871992

Subject(s)

Ethics, Medical , Informed Consent , Mental Healing , Religion , Humans , Inpatients/psychology , Religion and Medicine

10.

Karl Landsteiner: blood groups foreseen?

Hammerschmidt, D E.

J Lab Clin Med ; 135(2): 216, 2000 Feb.

Article in English | MEDLINE | ID: mdl-10695668

Subject(s)

Blood Group Antigens/history , Austria , Blood Coagulation , Hematology/history , History, 20th Century , Humans

11.

Adherence of staphylococci.

Hammerschmidt, D E.

J Lab Clin Med ; 135(1): 106, 2000 Jan.

Article in English | MEDLINE | ID: mdl-10638701

Subject(s)

Bacterial Adhesion , Silicone Elastomers , Staphylococcus/physiology , Microscopy, Electron, Scanning , Staphylococcus/ultrastructure

12.

Disseminated histoplasmosis following prolonged low-dose methotrexate therapy.

Roy, V; Hammerschmidt, D E.

Am J Hematol ; 63(1): 59-60, 2000 Jan.

Article in English | MEDLINE | ID: mdl-10602172

Subject(s)

Antirheumatic Agents/adverse effects , Histoplasmosis/etiology , Methotrexate/adverse effects , Adult , Antirheumatic Agents/administration & dosage , Bone Marrow/microbiology , Bone Marrow/pathology , Female , Histoplasma/isolation & purification , Histoplasmosis/diagnosis , Histoplasmosis/microbiology , Humans , Methotrexate/administration & dosage

13.

A rack of bifid ribs.

Hammerschmidt, D E.

J Lab Clin Med ; 134(6): 668, 1999 Dec.

Article in English | MEDLINE | ID: mdl-10595796

Subject(s)

Basal Cell Nevus Syndrome/pathology , Ribs/abnormalities , Humans

14.

Development of a gutless vector.

Hammerschmidt, D E.

J Lab Clin Med ; 134(3): C3, 1999 Sep.

Article in English | MEDLINE | ID: mdl-10482319

Subject(s)

Genetic Vectors , Adenoviridae/genetics , Animals , Genetic Therapy , Helper Viruses/genetics

15.

It's as simple as black and white! Race and ethnicity as categorical variables.

Hammerschmidt, D E.

J Lab Clin Med ; 133(1): 10-2, 1999 Jan.

Article in English | MEDLINE | ID: mdl-10385475

Subject(s)

Ethnicity , Publishing/standards , Racial Groups , Humans

16.

Professor Antoine Lacassagne and anti-estrogen therapy.

Hammerschmidt, D E.

J Lab Clin Med ; 133(5): 516, 1999 May.

Article in English | MEDLINE | ID: mdl-10235135

Subject(s)

Breast Neoplasms/therapy , Estrogen Antagonists/therapeutic use , Female , France , History, 20th Century , Humans , Receptors, Estrogen/drug effects , Risk Factors

17.

The first commercial bottle of aspirin: March 6, 1899.

Hammerschmidt, D E.

J Lab Clin Med ; 132(6): 556, 1998 Dec.

Article in English | MEDLINE | ID: mdl-9851747

Subject(s)

Aspirin/history , Drug Packaging/history , Germany , History, 19th Century , History, 20th Century , History, Ancient

18.

Xanthium strumarium.

Hammerschmidt, D E.

J Lab Clin Med ; 132(1): 86, 1998 Jul.

Article in English | MEDLINE | ID: mdl-9665377

Subject(s)

Drugs, Chinese Herbal/therapeutic use , Glomerulonephritis, IGA/drug therapy , Plants, Medicinal , Humans

19.

The fortieth anniversary of thrombopoietin (or is it the fiftieth?).

Hammerschmidt, D E.

J Lab Clin Med ; 131(6): 557-8, 1998 Jun.

Article in English | MEDLINE | ID: mdl-9626991

Subject(s)

Thrombopoietin/history , Animals , History, 20th Century , Humans

20.

Transfer of surface markers.

Hammerschmidt, D E.

J Lab Clin Med ; 131(3): 286, 1998 Mar.

Article in English | MEDLINE | ID: mdl-9523854

Subject(s)

CD4 Antigens/metabolism , Glycosylphosphatidylinositols/metabolism , CD4 Antigens/ultrastructure , Cell Communication/physiology , Cell Membrane/ultrastructure , Cells, Cultured , Humans , Microspheres

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