ABSTRACT
Cystic echinococcosis, caused by the larval stage of Echinoccocus granulosus, is a global public health threat. The aim of this study was to determine the demographic and clinical characteristics of cases of primary and secondary hydatid cyst in the west of the Islamic Republic of Iran. A retrospective record review was made in 7 public and private hospitals in Kermanshah from 2004 to 2009. Of 526 files of suspected cases analysed, 291 cases of hydatid cyst had been operated upon and confirmed. Of the patients, 51.5% were females, 57.7% lived in urban and suburban areas and the largest age group (17.5%) was 31-40 years. The major organs involved were liver (64.9%) and lung (26.8%) and 18 cases (6.2%) were confirmed as secondary hydatidosis. Most patients (79.4%) had been treated with albendazole. Kermanshah province should be considered an endemic region for human hydatid cyst disease; greater efforts in prevention are needed.
Subject(s)
Albendazole/therapeutic use , Anthelmintics/therapeutic use , Echinococcosis/epidemiology , Adolescent , Age Distribution , Aged , Aged, 80 and over , Child , Child, Preschool , Echinococcosis/drug therapy , Echinococcosis/surgery , Endemic Diseases , Female , Humans , Infant , Iran/epidemiology , Male , Middle Aged , Recurrence , Retrospective Studies , Rural Health/statistics & numerical data , Sex Distribution , Urban Health/statistics & numerical data , Young AdultABSTRACT
Cystic echinococcosis, caused by the larval stage of Echinoccocus granulosus, is a global public health threat. The aim of this study was to determine the demographic and clinical characteristics of cases of primary and secondary hydatid cyst in the west of the Islamic Republic of Iran. A retrospective record review was made in 7 public and private hospitals in Kermanshah from 2004 to 2009. Of 526 files of suspected cases analysed, 291 cases of hydatid cyst had been operated upon and confirmed. Of the patients, 51.5% were females, 57.7% lived in urban and suburban areas and the largest age group [17.5%] was 31-40 years. The major organs involved were liver [64.9%] and lung [26.8%] and 18 cases [6.2%] were confirmed as secondary hydatidosis. Most patients [79.4%] had been treated with albendazole.Kermanshah province should be considered an endemic region for human hydatid cyst disease; greater efforts in prevention are needed
Subject(s)
Liver , Lung , Albendazole , Retrospective Studies , Recurrence , EchinococcosisABSTRACT
BACKGROUND: Visceral leishmaniasis (VL) or kala-azar is a parasitic disease caused by the species of Leishmania donovani complex. It is endemic in some parts of provinces of Iran. According to the reported cases of VL in Kermanshah Province in recent years, this study was conducted to determine the seroprevalence of VL in high risk villages of the province. METHODS: Totally, 1622 serum samples obtained from children under 15 years old and 178 from adults in 22 villages of studied areas. Serum samples were examined by direct agglutination test (DAT) for the detection of anti-Leishmania antibodies. Data were analyzed using SPSS software ver.11.5. RESULTS: Only 6 serum samples (0.33%) showed anti-Leishmania antibodies against L.infantum at titers ≥ 1/3200. Four of the seropositive cases had a history of kala-azar and Leishman bodies were seen in their bone marrows. The highest (0.5%) and lowest (0.29%) seroprevalence was seen in the age groups of 5-9 and 10-14 years old, respectively. None of the adults were seropositive. There were not any significant differences between the rate of seropositivity in males (0.36%) and females (0.31%). 66.7% of seropositive individuals showed clinical manifestations. The most important symptoms in Kala-azar patients were fever, hepato-spleenomegally and anemia. CONCLUSION: Kala-azar is occurred sporadically in Kermanshah Province. But presence of significant number of positive sera confirms the necessity for attention of people and clinicians to kala-azar.
ABSTRACT
BACKGROUND: Hydatidosis is the larval stage of the Echinococcusgranulosus. This disease is endemic in Iran. There are many studies about hydatidosis in different regions of the country, but there is not any information about the disease in Kermanshah Province. This article will review all available data about hydatidosis in this province. METHODS: Using web based search engines and a survey on medical student's theses, all the information about hydatid cysts in the province from 1986 -2008 was collected. RESULTS: During these twenty years, at least 482 proven cases of hydatid cyst have been identified in the province. Accordingly, the trend of hydatid cyst operation in the province has been growing and the average annual number of cases has reached 1.41/100,000. Frequency of disease in urban areas was slightly higher than rural areas and the rate of infection in housewives was more than others. CONCLUSION: Because of the growing trend of hydatid cyst operation in Kermanshah Province, which may be due to many different reasons, this province should be considered as one of the important endemic regions of hydatidosis in Iran.
ABSTRACT
Using direct agglutination tests, a survey of visceral leishmaniasis was carried out among children and adults from 13 villages and from nomadic tribes in Bushehr province during 1998-99. Of the 1496 plasma samples, the overall seropositive rate (titres > or = 1:3200) was 3.4%. Almost all cases (94.1%) were in children under 10 years old. Eighteen patients were diagnosed with kala azar; fever and splenomegaly were the predominant signs and symptoms. Parasitology and serology examinations of local animals identified dogs and jackals infected with Leishmania infantum. Suggestions for control of visceral leishmaniasis in this area are to eliminate stray dogs, identify cases among humans and suspected leashed dogs, and treat infected individuals.
Subject(s)
Disease Reservoirs , Dog Diseases/epidemiology , Leishmaniasis, Visceral/epidemiology , Leishmaniasis, Visceral/veterinary , Adolescent , Adult , Age Distribution , Agglutination Tests , Animals , Antibodies, Protozoan/blood , Carnivora/parasitology , Child , Child, Preschool , Disease Reservoirs/statistics & numerical data , Disease Reservoirs/veterinary , Dog Diseases/blood , Dog Diseases/prevention & control , Dogs , Female , Fever/parasitology , Humans , Infant , Iran/epidemiology , Leishmania donovani/immunology , Leishmaniasis, Visceral/blood , Leishmaniasis, Visceral/prevention & control , Male , Population Surveillance , Seroepidemiologic Studies , Splenomegaly/parasitology , Transients and Migrants/statistics & numerical data , Zoonoses/epidemiologyABSTRACT
Using direct agglutination tests, a survey of visceral leishmaniasis was carried out among children and adults from 13 villages and from nomadic tribes in Bushehr province during 1998-99. Of the 1496 plasma samples, the overall seropositive rate [titres > or = 1:3200] was 3.4%. Almost all cases [94.1%] were in children under 10 years old. Eighteen patients were diagnosed with kala azar; fever and splenomegaly were the predominant signs and symptoms. Parasitology and serology examinations of local animals identified dogs and jackals infected with Leishmania infantum. Suggestions for control of visceral leishmaniasis in this area are to eliminate stray dogs, identify cases among humans and suspected leashed dogs, and treat infected individuals
