ABSTRACT
OBJECTIVE: To explore the clinical value of color Doppler ultrasound in patients with prethrombotic state (PTS). METHODS: From October 2011 to November 2012, a total of 201 patients were diagnosed with PTS. There were 95 males and 106 females with an average age of 52 years (range: 15-78). They were divided into intervention and observation groups on the basis of drug intervention. And the relevant literatures were reviewed and the images of color Doppler ultrasound before and after treatment compared. RESULTS: Before treatment, blood flow peak rates of common femoral, popliteal and calf intermuscular veins were (0.16 ± 0.03), (0.14 ± 0.03) and (0.13 ± 0.02) m/s; after treatment, (0.19 ± 0.03), (0.17 ± 0.03) and (0.15 ± 0.01) m/s respectively. The peak flow increased and sluggish flow decreased or disappeared in 152 PS patients. It indicated a relief or an obvious resolution of hypercoagulable state. And the symptom of lower extremity soreness was greatly relieved. Among 49 patients without drug intervention, severe full-lumen storm floating occurred in 12 cases. And 8 of them suffered deep vein thrombosis within 2 weeks. The incidence of thrombus was 66.7%. CONCLUSION: Color Doppler ultrasound may detect and assess PTS effectively so as to guide effective interventions.
