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1.
Saudi Med J ; 25(10): 1489-91, 2004 Oct.
Article in English | MEDLINE | ID: mdl-15494830

ABSTRACT

Eosinophilic granuloma EG is a benign self-limiting disease, which belongs to the spectrum of Langerhans' cell histiocytosis LCH. The etiology of LCH remains unknown, although the evidence indicates that it is a clonal proliferative disorder of Langerhans cells, it has also been characterized as reactive disorder, neoplastic process and a berrant immune response. Eosinophilic granuloma is characterized by single or multiple skeletal lesions occurring predominately in children, adolescents and young adults, it accounts for 70% of LCH. It is more common in males, and the common sites are the skull, mandible, ribs, spines and long bones particularly the femur and the humerus. The estimated incidence of EG is 3-4 per million of the population. Vertebral bone involvement is rarely seen and usually affects the vertebral body. We are reporting an unusual case of EG in a female child presented with a solitary lesion at posterior element of lumbar vertebra.


Subject(s)
Eosinophilic Granuloma/diagnosis , Lumbar Vertebrae/pathology , Spinal Diseases/diagnosis , Biopsy, Needle , Bone Transplantation/methods , Child , Combined Modality Therapy , Curettage/methods , Eosinophilic Granuloma/surgery , Female , Follow-Up Studies , Humans , Immunohistochemistry , Low Back Pain/diagnosis , Low Back Pain/etiology , Lumbar Vertebrae/surgery , Risk Assessment , Severity of Illness Index , Spinal Diseases/surgery , Tomography, X-Ray Computed , Treatment Outcome
2.
Saudi Med J ; 25(9): 1264-6, 2004 Sep.
Article in English | MEDLINE | ID: mdl-15448781

ABSTRACT

Eosinophilic granuloma EG is a well-recognized benign form of Langerhans cell histiocytosis, most commonly involving the skull bones. In this paper, we report an 8-year-old girl with EG of posterior element of vertebra; she had complete resolution with surgical curettage and bone grafting.


Subject(s)
Eosinophilic Granuloma/diagnostic imaging , Eosinophilic Granuloma/surgery , Spinal Diseases/diagnostic imaging , Spinal Diseases/surgery , Bone Transplantation/methods , Child , Combined Modality Therapy , Curettage/methods , Eosinophilic Granuloma/pathology , Female , Follow-Up Studies , Humans , Lumbar Vertebrae/pathology , Risk Assessment , Saudi Arabia , Spinal Diseases/pathology , Tomography, X-Ray Computed , Treatment Outcome
3.
Saudi Med J ; 25(2): 225-8, 2004 Feb.
Article in English | MEDLINE | ID: mdl-14968225

ABSTRACT

Portal vein thrombosis is a recognized complication after splenectomy in beta-thalassemia major due to the chronic hypercoagulable state which has been recognized to exist in childhood thalassemia and contribute to thromboembolic events. We are reporting one patient with beta-thalassemia major developed portal vein thrombosis following splenectomy.


Subject(s)
Portal Vein , Postoperative Complications , Splenectomy , Venous Thrombosis , beta-Thalassemia/surgery , Abdominal Pain/etiology , Child , Humans , Male , Postoperative Complications/diagnosis , Postoperative Complications/drug therapy , Saudi Arabia , Ultrasonography, Doppler, Color , Venous Thrombosis/complications , Venous Thrombosis/diagnosis , Venous Thrombosis/drug therapy
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