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Appl Opt ; 44(24): 5055-68, 2005 Aug 20.
Article in English | MEDLINE | ID: mdl-16121790

ABSTRACT

A low-cost semiconductor red laser light delivery system for esophagus cancer treatment is presented. The system is small enough for insertion into the patient's body. Scattering elements with nanoscale particles are used to achieve uniform illumination. The scattering element optimization calculations, with Mie theory, provide scattering and absorption efficiency factors for scattering particles composed of various materials. The possibility of using randomly deformed spheres and composite particles instead of perfect spheres is analyzed using an extension to Mie theory. The measured radiation pattern from a prototype light delivery system fabricated using these design criteria shows reasonable agreement with the theoretically predicted pattern.


Subject(s)
Catheterization/instrumentation , Computer-Aided Design , Esophageal Neoplasms/drug therapy , Laser Therapy , Photochemotherapy/instrumentation , Transducers , Catheterization/methods , Equipment Design , Equipment Failure Analysis , Feasibility Studies , Humans , Nanotubes , Photochemotherapy/methods , Photosensitizing Agents/therapeutic use , Scattering, Radiation , Semiconductors
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