ABSTRACT
Background and objectives SIVI is a standardized extract prepared using the aerial parts of Passiflora incarnata developed to enhance the quality of sleep. ââââââThe objective of the present study was to the evaluate efficacy and safety of SIVI (Passiflora incarnata extract) in the management of stress and sleep problems in Indian participants in a randomized, double-blind, placebo-controlled, clinical study. Materials and methods A total of 65 participants with stress and insomnia were randomized to two groups with 32 in the SIVI (Passiflora incarnata extract) group and 33 in the placebo group. Subjects were asked to take the test substance along with water at bedtime for 30 days. The Perceived Stress Scale, quality of life using the General Health Questionnaire (GHQ-12) scale, and Insomnia Severity Index were assessed on day 1, day 15, and day 30. Results Passiflora incarnata extract showed a statistically significant reduction in the mean score of stress on the Perceived Stress Scale and significantly increased the mean score of total sleep time compared to placebo. The general psychological health was found to be significantly improved in the SIVI (Passiflora incarnata extract) group compared to the placebo group on day 15 and day 30. SIVI (Passiflora incarnata extract) did not show any adverse effects. Conclusions The results of the current study indicate that Passiflora incarnata extract is beneficial in the management of stress and helps to improve sleep quality in subjects with stress and insomnia.
ABSTRACT
Background: Smoking is a major predisposing factor for many health problems including cancers, vascular disorders, etc., To quit smoking is the only solution to prevent them. Various medicinal and non-medicinal methods are used worldwide for the same. The present study evaluates the effect of a nicotine free herbal formulation containing ingredients like Mucuna pruriens, Withania somnifera, Bacopa monnieri, etc., for cessation of smoking and its effects on other health parameters related to smoking. Materials and Methods: The present study was a placebo controlled, double blind, randomized, and multi-centric clinical study conducted at three clinical sites in India. After ethical approval and informed consent, all participants were given Smotect Tablets or Placebo tablets in a dose of 2 tablets twice daily for 90 days. A total of 103 participants (52 in trial group and 51 in placebo group) completed the study. Evaluation of cessation of smoking was done along with other parameters like measurement of lung capacity, clinical assessment, and laboratory investigations before and after the study. Results: A significant reduction in smoking as well as in the alveolar Carbon monoxide (p < 0.05) and Carboxyhemoglobin levels (p < 0.05) were observed with the use of Smotect tablets as compared to placebo over a period of 90 days. Significant improvement was also observed in quality of life, energy and stamina levels, and reduction of stress level. Smotect tablets were found to be safe without causing any adverse effects. Conclusion: Smotect Tablets is an effective and safe remedy for cessation of smoking and reducing other effects related to smoking.
ABSTRACT
Agni (digestive fire), Prakruti (constitution), Dhatusarata (tissue excellence), Dosha (bio-energies) are the specialties of Ayurveda on which diagnosis, treatment and research are based. The description of Dhatusarata (tissue excellence) has been given under Dashavidha Pariksha (tenfold examination) in Charak Samhita, Viman Sthana, 8(th) chapter. Some qualities, which are mentioned in Dhatusarata are difficult to assess, e.g. Sukha, Aishwarya, Upabhoga, Bala, etc., There is a need to develop some quantitative parameters to measure these qualities according to tissue excellence i.e. Dhatusarata. By assessing Dhatu Sarata, one can judge the true strength of a particular Dhatu but only the ability or strength is not enough to get success; the liking or interest is also essential to achieve success. The purpose of this study is to elaborate the concept of Dhatusarata and reveal different aspects of Sukha according to the quality of that particular Dhatu in context of vocational guidance. It will help to establish interrelationship between Dhatusarata and vocational guidance. It will be assessed whether this Sukha quality is merely happiness or having different shades according to the excellence of Dhatus and whether this study is useful in guiding the person to choose appropriate profession, which will be according to his liking and ability. It has been concluded that shades of Sukha quality varies with particular Dhatusaras, which may be helpful in guiding a suitable profession to an individual which will be according to his ability and liking i.e. Sukha for intimate success.
ABSTRACT
Horse-shoe Fistula is a big challenge for both Modern and Ayurvedic Surgeons. We can correlate this with 'Shambukawarta Bhagandara' described by Sushruta. Here, fistula forms secondary to an ischiorectal abscess and both the ischiorectal fossae are involved. Also, they open posteriorly into the anal canal, at the 6 o'clock position, and are associated with a big cavity lying superior (above the levatorani). Therefore, in such a clinical feature neither Fistulotomy ('Wanley operation') nor 'Ksharasutra' treatment alone, prove useful. After going through this, we can say that there is a definite need for newer surgical innovative techniques, to tackle this challenging disease. An integral approach of 'Fistulectomy along the arms of the Horse-shoe fistula with Ksharasutra ligation' in the remaining track connected to the anal canal, and drainage of the postanal space abscess, proved to be very successful. We have tried the same technique with very good results. No recurrence was found in the patients during the follow-up period of three years. The given diagrammatic presentation of the plan of surgery will help to understand the procedure.
