Subject(s)
DNA-Binding Proteins/chemistry , Nuclear Proteins/chemistry , Protein Isoforms/chemistry , Protein Processing, Post-Translational , Trans-Activators/chemistry , Tumor Suppressor Protein p53/chemistry , Tumor Suppressor Proteins/chemistry , Animals , Apoptosis/genetics , Cell Cycle/genetics , Cell Cycle Proteins/genetics , Cell Cycle Proteins/metabolism , Cell Nucleus/metabolism , Cell Transformation, Neoplastic/genetics , Cell Transformation, Neoplastic/metabolism , DNA/metabolism , DNA-Binding Proteins/genetics , DNA-Binding Proteins/metabolism , Humans , Mutation , Neoplasms/genetics , Neoplasms/metabolism , Nuclear Proteins/genetics , Nuclear Proteins/metabolism , Promoter Regions, Genetic/genetics , Protein Isoforms/genetics , Protein Isoforms/metabolism , Protein Structure, Tertiary , Trans-Activators/genetics , Trans-Activators/metabolism , Transcription Factors , Transcriptional Activation , Tumor Protein p73 , Tumor Suppressor Protein p53/genetics , Tumor Suppressor Protein p53/metabolism , Tumor Suppressor Proteins/genetics , Tumor Suppressor Proteins/metabolismABSTRACT
Cardiac sonographers at a regional medical center have experienced carpal tunnel syndrome symptoms and other work-related musculoskeletal injuries. The nationwide incidence of these problems was not known. A questionnaire pertaining to possible causes of work-related injuries was developed and distributed to 225 cardiac sonographers. A 47% response rate was achieved with 72% female respondents. Eighty-six percent reported one or more physical symptoms. Only 3% of respondents had been diagnosed with carpal tunnel syndrome. Posture correlated significantly with other work-related musculoskeletal injuries. High-pressure hand grip correlated significantly with carpal tunnel syndrome symptoms. No other strong relations with physical symptoms were found. The contribution of specific factors to musculoskeletal problems experienced by cardiac sonographers was difficult to determine.
