Consequences of frequent nocturnal gastro-oesophageal reflux disease among employed adults: symptom severity, quality of life and work productivity.

BACKGROUND: Effects of frequent nocturnal symptoms of gastro-oesophageal reflux disease (GERD-FNS) on health-related quality of life (HRQOL) and work productivity are not well documented. AIM: To assess symptom severity, production loss, and HRQOL among employed adults with and without GERD-FNS. METHODS: Using several validated outcome measures in a web survey design, GERD was pre-specified as GERD Symptom and Medication Questionnaire score >9, and > or =1 episode of heartburn or acid regurgitation during the preceding week. GERD-FNS patients were those reporting > or =2 symptom-nights during the previous week; their outcomes were compared with those of patients having minimal or no nocturnal symptoms (GERD-NNS) and vs. non-GERD controls. RESULTS: Data were collected from 1002 GERD patients (476 GERD-FNS, 526 GERD-NNS) and 513 controls. Severe symptoms were more common, sleep abnormalities were more frequent (P < 0.0001) and SF-36 scores lower (P < 0.05, all scores) among GERD-FNS patients vs. GERD-NNS patients. GERD-related work loss was greater among those with GERD-FNS vs. GERD-NNS (P < 0.0001). Work loss and functional limitations were more pronounced when comparing GERD-FNS cases vs. non-GERD controls. CONCLUSION: Employed adults with frequent nocturnal GERD report more severe symptoms, and are associated with impaired sleep, HRQOL and work productivity compared with controls and patients with minimal or no nocturnal symptoms.

Three last letters identify most female first names.

The last spelled letter often indicates the sex of first names. Most female names end with the last letter a, e, or i. Female names are distinctive and therefore easy to identify because of the small number of predominantly female endings. Most male names end with one of 19 last letters. Two last letters, h and y, occur with similar frequency for both sexes. The cultural tradition of higher status for men contributes to the avoidance of predominantly female last letters for male names. A female name with a predominantly male last letter therefore occurs more often than a male name with a predominantly female last letter. The findings were obtained from the 500 most frequent first names given to males and females in Pennsylvania in 1990.

The Vale of Leven health promotion project.

A two stage health promotion programme is in progress in the Vale of Leven in Dunbartonshire. The first stage has been completed within a local factory (Polaroid UK Limited), the largest private employer in the district. A total of 1205 employees, representing 87% of the workforce, took part in the programme and were initially screened for coronary artery risk factors. Blood pressure, serum cholesterol, body composition and aerobic fitness were measured and smoking habits determined. Aspects of lifestyle were assessed by questionnaire. All employees whose initial cholesterol concentration was greater than 6.5 mM were given simple dietary advice and their cholesterol concentration thereafter remeasured. Eighty-two per cent of these men and 72% of these women succeeded in reducing their cholesterol, the men by a mean of 1.3 mM, the women by a mean of 0.7 mM. The health initiatives undertaken within the factory at the same time as screening are also described in this paper.