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1.
Am J Public Health ; 100(4): 635-7, 2010 Apr.
Article in English | MEDLINE | ID: mdl-20167898

ABSTRACT

We compared self-reported child labor violations between teenagers with and without work permits. Data were obtained from a school-based survey of working teenagers in 16 randomly selected high schools in North Carolina. We examined associations between work hour violations, hazardous order violations (performance of illegal tasks), and possession of a work permit. Work permits appear to be protective against performance of illegal tasks but not against work hour violations, demonstrating the need for stricter enforcement policies and improvements in work permit screening processes.


Subject(s)
Employment/statistics & numerical data , Schools , Adolescent , Child , Data Collection , Employment/legislation & jurisprudence , Humans , Licensure/legislation & jurisprudence , Licensure/statistics & numerical data , North Carolina/epidemiology , Occupational Health , Schools/statistics & numerical data
2.
Pediatr Res ; 65(5): 504-8, 2009 May.
Article in English | MEDLINE | ID: mdl-19190542

ABSTRACT

The function of the cardiovascular system during hypoxia is an important determinant of neurologic outcome. Oscillations in blood pressure, particularly type-3 waves with a duration of 10 to 160 s, have been shown to occur in the presence of hypoxia in the neonatal rat. The aim of this study was to determine the characteristics and occurrence of type-3 waves in the neonatal piglet and any relationship to neurologic damage after acute global hypoxia. Hypoxia/hypercarbia was induced in 32 anesthetized piglets by reducing the fraction of inspired oxygen to 0.1 and the ventilation rate from 30 to 10 breaths per minute for 45 min. The degree of neurologic damage was assessed using both physiologic (EEG amplitude and cerebral impedance at 6 h posthypoxia) and structural (microtubule associated protein-2 immunohistochemistry) markers. Type-3 waves in cardiovascular function occurred in 56% of animals. An oscillating pattern was significantly associated with less neurologic damage (p = 0.01) and a lower duration of hypotension during hypoxia (p = 0.02), and occurred more frequently in females (p = 0.024).


Subject(s)
Cardiovascular System/physiopathology , Hemodynamics , Hypoxia, Brain/etiology , Hypoxia/physiopathology , Neurons/pathology , Acute Disease , Animals , Animals, Newborn , Biomarkers/metabolism , Blood Pressure , Cerebrovascular Circulation , Disease Models, Animal , Electroencephalography , Female , Heart Rate , Hypoxia/complications , Hypoxia/pathology , Hypoxia, Brain/pathology , Hypoxia, Brain/physiopathology , Immunohistochemistry , Male , Microtubule-Associated Proteins/metabolism , Neurons/metabolism , Periodicity , Regional Blood Flow , Severity of Illness Index , Sex Factors , Skin/blood supply , Swine
3.
Stress ; 12(4): 294-304, 2009 Jul.
Article in English | MEDLINE | ID: mdl-18951250

ABSTRACT

Perinatal asphyxia is a significant contributor to neonatal brain injury. However, there is significant variability in neurological outcome in neonates after global hypoxia-ischemia. The aims of this study were to identify which physiological response/s during global hypoxia-ischemia influence the severity of brain injury and to assess their relative importance. Hypoxia/hypercapnia was induced in 20 anaesthetized piglets by reducing the inspired oxygen fraction to 10% and the ventilation rate from 30 to 10 breaths per minute for 45 min. Neurological outcome was assessed using functional markers including cerebral function amplitude (via electroencephalography) and cerebral impedance, and the structural marker microtubule associated protein-2 by immunohistochemistry at 6 h post hypoxia. Significant variability in neurological outcome was observed following the constant hypoxia/hypercapnia insult. There was a high degree of variability in cardiovascular function (mean arterial blood pressure and heart rate) and serum cortisol concentrations in response to hypoxia. More effective maintenance of cardiovascular function and higher serum cortisol concentrations were associated with a better outcome. These two variables were strongly associated with neurological outcome, and together explained 68% of the variation in the severity of neurological outcome. The variability in the cardiovascular and cortisol responses to hypoxia may be a more important determinant of neurological outcome then previously recognized.


Subject(s)
Hydrocortisone/blood , Hypoxia-Ischemia, Brain/physiopathology , Animals , Animals, Newborn , Blood Pressure , Brain Edema/physiopathology , Cardiovascular Physiological Phenomena , Electric Impedance , Electroencephalography , Female , Heart Rate , Hypercapnia , Hypoxia-Ischemia, Brain/blood , Immunohistochemistry , Male , Microtubule-Associated Proteins/metabolism , Swine
4.
Arch Pediatr Adolesc Med ; 160(7): 721-7, 2006 Jul.
Article in English | MEDLINE | ID: mdl-16818838

ABSTRACT

OBJECTIVE: To describe the working conditions of adolescents employed in construction in North Carolina, documenting hazards, safety practices, and prohibited activities. DESIGN: A cross-sectional telephone survey. SETTING: North Carolina. PARTICIPANTS: Adolescents (aged <18 years) with work permits for the construction industry in North Carolina during summer 2001. MAIN OUTCOME MEASURES: Types of jobs, work tasks, supervisory conditions, tools, equipment, and processes. RESULTS: A total of 187 survey respondents were in this study. Adolescents were employed in varied construction settings and business types. Nineteen of the 187 permitted workers were younger than 16 years, despite prohibitions against their employment in construction unless working for their parents. The remainder (n = 168) were working legally based on age, but most performed prohibited tasks. In fact, 84% of all the 16- to 17-year-olds had performed at least 1 clearly prohibited task and 47% had performed 3 or more. Although most reported being supervised and working with others, approximately 19% of all respondents reported working where they were not in hearing distance of other workers. Data were collected from teenagers with work permits, suggesting that these adolescents may work for more responsible employers. If violations of child labor laws exist in this group, it is likely that adolescents without permits are exposed to even greater hazards and violations. CONCLUSION: Involvement of teenagers in dangerous and/or prohibited tasks is cause for concern and suggests a pressing need to examine the enforcement of existing laws and the need for additional protection.


Subject(s)
Facility Design and Construction , Occupational Exposure/legislation & jurisprudence , Occupational Exposure/statistics & numerical data , Occupational Health/legislation & jurisprudence , Occupational Health/statistics & numerical data , Workplace/legislation & jurisprudence , Adolescent , Cross-Sectional Studies , Humans , North Carolina , Workload/legislation & jurisprudence , Workload/statistics & numerical data , Workplace/statistics & numerical data
5.
Buenos Aires; Grijalbo; 1a. ed; 1974. 402 p. 20cm.
Monography in Spanish | LILACS-Express | BINACIS | ID: biblio-1195165
6.
Buenos Aires; Ediciones Grijalbo; 2a.ed; 1977. 401 p. 20 cm.
Monography in Spanish | LILACS-Express | BINACIS | ID: biblio-1199847
7.
Buenos Aires; Grijalbo; 1a. ed; 1974. 402 p. 20cm. (69488).
Monography in Spanish | BINACIS | ID: bin-69488
8.
Buenos Aires; Ediciones Grijalbo; 2a.ed; 1977. 401 p. 20 cm. (75768).
Monography in Spanish | BINACIS | ID: bin-75768
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