Bombesin improves rats' operant responding maintained by a differential-reinforcement-of-low-rates schedule of food reinforcement.

The present study examined rats' responding on a differential-reinforcement-of-low-rates schedule of food reinforcement following intraperitoneal injections of various doses of bombesin (4, 6, 8, 16, 32 micrograms/kg). Analyses indicated that only the 6 micrograms/kg dosage improved DRL responding. The findings are consistent with prior research examining bombesin's effect on operant behavior and support the notion that bombesin induces satiety rather than malaise.