Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Ocul Immunol Inflamm ; 20(3): 163-70, 2012 Jun.
Article in English | MEDLINE | ID: mdl-22506485

ABSTRACT

PURPOSE: To examine the relation between uveitis and common variable immunodeficiency (CVID). METHODS: Retrospective analysis of patients included in the French DEFI cohort of adults with CVID and of patients identified by reviewing the literature. RESULTS: Four patients were identified in the DEFI study (frequency of uveitis: 1.6%). The course of uveitis was not changed in the patients who started intravenous immunoglobulins replacement therapy after CVID diagnosis. Ten cases of CVID-associated uveitis were listed in the literature. Overall, among the 14 patients, uveitis was always chronic, usually bilateral (n = 11) and granulomatous (n = 9). Seven patients presented with a "sarcoid-likeâ syndrome. Nine patients had granulomatous uveitis suggestive of ocular sarcoidosis. Five patients were treated with local corticosteroids, and 9 required systemic treatment (corticosteroids alone n = 5 and/or immunosuppressive agents n = 4). CONCLUSIONS: CVID can be associated with uveitis. Since uveitis can reveal the immunodeficiency, CVID diagnosis should be considered at the time of uveitis diagnosis.


Subject(s)
Common Variable Immunodeficiency/diagnosis , Uveitis/diagnosis , Adolescent , Adrenal Cortex Hormones/therapeutic use , Adult , Clinical Trials as Topic , Common Variable Immunodeficiency/complications , Common Variable Immunodeficiency/drug therapy , Female , France , Granulomatous Disease, Chronic/diagnosis , Granulomatous Disease, Chronic/drug therapy , Humans , Immunoglobulins, Intravenous/therapeutic use , Immunosuppressive Agents/therapeutic use , Male , Multicenter Studies as Topic , Retrospective Studies , Sarcoidosis/diagnosis , Sarcoidosis/drug therapy , Uveitis/drug therapy , Uveitis/etiology , Young Adult
SELECTION OF CITATIONS
SEARCH DETAIL
...