ABSTRACT
INTRODUCTION: There is no consensus on the optimal surgery for splenic flexure cancers. METHODS: Review of a prospectively maintained database of patients with splenic flexure cancer undergoing either a right extended hemicolectomy or left hemicolectomy at a tertiary care cancer hospital from 14.5.2010 to 16.9.2021. The primary outcome measures were postoperative morbidity and hospital stay with secondary outcomes being overall survival, disease-free survival, and long-term patient reported functional and quality of life outcomes. RESULTS: The demographic variables were evenly distributed between groups, and median follow-up was 44 months. The groups were comparable in terms of postoperative morbidity (Clavien-Dindo complication ≥ 3a 10.6% vs 10%, p = 0.322) and hospital stay (8 days vs 7 days, p = 0.316). Oncological outcomes were similar in both groups (3-year disease-free survival 71.8% vs 67.8%, p = 0.877, and 3-year overall survival 83.9% vs 75.8%, p = 0.787), and long-term patient-reported functional outcomes were excellent in both groups. CONCLUSION: Oncological outcomes, post operative morbidity, and long-term patient reported functional outcomes are comparable in patients undergoing either a right extended or left hemicolectomy for splenic flexure cancer.
Subject(s)
Colon, Transverse , Colonic Neoplasms , Laparoscopy , Humans , Colon, Transverse/surgery , Colonic Neoplasms/surgery , Quality of Life , Treatment Outcome , Colectomy , Retrospective StudiesABSTRACT
penetrating keratoplasty was done.Isolated stromal graft rejection was noticed 3 weeks after penetrating keratoplasty,which was confirmed on histopathology.Repeat penetrating keratoplasty 6 months later also had same fate.Diagnosis and management of isolated stromal graft rejection is a very challenging situation.
ABSTRACT
Follicular adenomas of the thyroid may be subjected to degenerative changes like hemorrhagic and cystic changes, fibrosis, and calcification. Mature bone formation is a rare phenomenon, but extramedullary hematopoiesis (EMH) has also been rarely reported in thyroid gland. The combination of mature bone formation and EMH is rarer and has been reported, in a single case report, in a multinodular goitre. We describe a case of follicular adenoma with histologically proven osseous metaplasia and mature bone formation with EMH in a middle- aged woman, which, to our knowledge, is the first case in English language literature.
Subject(s)
Adenoma/diagnosis , Adenoma/pathology , Hematopoiesis, Extramedullary , Ossification, Heterotopic , Thyroid Gland/pathology , Thyroid Neoplasms/diagnosis , Thyroid Neoplasms/pathology , Female , Humans , Middle AgedABSTRACT
Copper-catalyzed multicomponent reactions with sugar alkynes, sulfonyl azides, and amines to furnish glycosylated N-sulfonylamidines are reported. The reaction is established to be general in terms of different combinations of sugar alkyne, sulfonyl azide, and amines.
Subject(s)
Alkynes/chemistry , Amidines/chemical synthesis , Amines/chemistry , Azides/chemistry , Copper/chemistry , Sulfones/chemistry , Amidines/chemistry , Carbohydrates/chemistry , Catalysis , Glycosylation , Molecular Structure , StereoisomerismABSTRACT
Gastrointestinal tract infestation with Strongyloides stercoralis is common in the tropical and subtropical areas of the world. In an immunocompetent person, disease is generally asymptomatic. However, it has the potential to cause serious life threatening disease in an immunocompromised patient. We report a 55 years old immunocompetent person who presented with malabsorption secondary to strongyloides stercoralis infestation. Unusual infestations like strongyloides should also be considered while investigating malabsorption.
