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J Nat Med ; 62(3): 369-73, 2008 Jul.
Article in English | MEDLINE | ID: mdl-18404308

ABSTRACT

Two new flavonoids named castilliferol 1 and castillicetin 2, as well as a known compound, isochlorogenic acid 3, were isolated from the whole plant of Centella asiatica. Isolates 1 and 2 exhibited good antioxidant activity using 2,2-diphenyl-1-picryl hydrazyl radical solution with IC(50) values of 23.10 and 13.30, respectively. The structures of these isolates were determined by analytical and spectral data, including 1-D and 2-D NMR spectra.


Subject(s)
Centella/chemistry , Flavonoids/isolation & purification , Antioxidants/isolation & purification , Antioxidants/pharmacology , Biphenyl Compounds , Chlorogenic Acid/analogs & derivatives , Chlorogenic Acid/isolation & purification , Flavonoids/pharmacology , Inhibitory Concentration 50 , Magnetic Resonance Spectroscopy , Picrates , Plant Extracts/chemistry , Plant Extracts/pharmacology
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