A Case of Trigeminal Neuralgia Treated With Combination of Antihistamine, Montelukast, and Corticosteroid Nasal Spray.

Trigeminal neuralgia (TN) is a nerve disorder of the face associated with excruciating pain that occurs in paroxysms and can be initiated by even mild cutaneous stimuli. Diagnosis of TN is based on the patient's history and the diagnosis of exclusion. The first-line treatment usually comprises carbamazepine or oxcarbazepine. Herein we present a case of a 47-year-old female, diagnosed with idiopathic TN. Initially, she was commenced on carbamazepine, and later, she was switched to sodium valproate without any noticeable relief. However, she responded to treatment with combination therapy comprising antihistamine, montelukast, and corticosteroid nasal spray. To the best of our knowledge, no such case has been reported previously.

The Impact of Inflammatory Bowel Disease on Pregnancy and the Fetus: A Literature Review.

Inflammatory bowel disease (IBD) is a constellation of devastating chronic inflammatory changes in the bowel, either involving the large or small bowel or part of both. As it is widely diagnosed in the fertile age group, this disorder can present itself, very commonly, during pregnancy and thus a better understanding of the disease can be an important factor to influence the maternal and fetal well-being. Medications are what is considered the first line in the management of this disease to control the symptoms or keep the disease in remission. In addition to this, the drugs used to keep the disease in remission can also cause significant adverse effects on the patient and the new nurturing life preparing itself for the outside world. What the fetus gets from the mother will stay for life with the child. We conducted an electronic literature review search which highlights the significance and impact of sustained remission of IBD and the cautious use of various drugs during pregnancy for that purpose. In addition to the influences already mentioned, It is evident that nutritional deficiencies can also prevail with the advancing disease, something to manage as a side note as well. These deficiencies can have a definite effect on the fetus and may cause developmental malformations. In order to avoid this process, a systemic and joint approach should be curtailed. This can reduce the adverse outcomes associated with this ailment during pregnancy.