ABSTRACT
Several studies have shown a higher prevalence of radiological abnormalities among gymnasts. However, the types of radiological abnormalities associated with low back pain (LBP) have not been clarified. The hypothesis was that significant relationships between radiological abnormalities and LBP may be revealed by discriminating between the types of MRI abnormalities while considering confounding factors. The subjects were 104 Japanese collegiate gymnasts (men, 70; women, 34). The presence of LBP was evaluated using the questionnaire developed by Osaka City University (OCU Test). Magnetic resonance imaging (MRI) abnormalities were evaluated using T1- and T2-weighted MRI. The prevalence of more than 1 MRI abnormality in gymnasts was 47.1% (49/104). The chi-square test showed that the incidence of lumbar disc degeneration (LDDG) and limbus vertebra was significantly greater in gymnasts with LBP than in gymnasts without LBP. By using logistic regression analysis to analyze the concomitant environmental variables, only LDDG (odds ratio, 2.70; 95% confidence interval, 1.10-6.66) was selected as a statistically significant variable accounting for LBP. In conclusion, LDDG is a predictor for LBP in Japanese collegiate gymnasts.
Subject(s)
Gymnastics , Intervertebral Disc Degeneration/complications , Intervertebral Disc Displacement/complications , Low Back Pain/etiology , Lumbar Vertebrae , Magnetic Resonance Imaging , Spondylolisthesis/complications , Adolescent , Case-Control Studies , Female , Humans , Intervertebral Disc Degeneration/diagnosis , Intervertebral Disc Displacement/diagnosis , Logistic Models , Low Back Pain/diagnosis , Male , Spondylolisthesis/diagnosis , Surveys and Questionnaires , Young AdultABSTRACT
Several studies have shown higher frequencies of radiological abnormalities among gymnasts. Recently, the gene encoding the α1 chain of type XI collagen, (COL11A1) (rs 1676486), was associated with lumbar disc herniation in the Japanese population. We hypothesized that there was a significant relationship between abnormal magnetic resonance imaging (MRI) findings of the lumbar spine and the COL11A1 4603C/T gene polymorphism in collegiate gymnasts. Our study participants included 103 Japanese collegiate gymnasts (70 men and 33 women). Radiological abnormalities were evaluated using T1- and T2-weighted MRI. Genotyping for COL11A1 was performed for all the participants. By using logistic regression analysis, we observed significant associations between limbus vertebra and age (adjusted odds ratio=0.51, 95% confidence interval: 0.27-0.96), sporting experience (adjusted odds ratio=1.49, 95% confidence interval: 1.14-1.94), and a TT genotype (adjusted odds ratio=7.83, 95% confidence interval: 1.33-46.03). We conclude that a TT genotype of COL11A1 polymorphism may be a significant risk factor for limbus vertebra in Japanese collegiate gymnasts.
